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Lack of Stage-Specific Proteins in Coccoid Helicobacter pylori Cells

Department of Molecular Biology,¹ Central Core Facility for Protein Analysis,² Central Core Facility for Microscopy, Max-Planck-Institute for Infection Biology, Berlin, Germany³

Received 28 May 2004/ Returned for modification 5 July 2004/ Accepted 9 August 2004

Helicobacter pylori exists in two distinct forms, rod shaped or coccoid, in stomachs of infected patients. Based on in vitro proteome comparisons, there are no detectable coccoid-specific proteins, which argues against the specific adaptation of coccoid Helicobacter to distinct biological functions, such as enhanced persistence or transmission to other hosts.

Editor: J. T. Barbieri

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