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Infection and Immunity, December 2004, p. 7315-7317, Vol. 72, No. 12
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.12.7315-7317.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

In Vitro Model of Bartonella henselae-Induced Angiogenesis

James E. Kirby*

Department of Pathology, Division of Cancer Biology and Angiogenesis, Beth Israel Deaconess Medical Center, Boston, Massachusetts

Received 14 June 2004/ Returned for modification 27 July 2004/ Accepted 20 August 2004

Bartonella henselae is a gram-negative pathogen that causes angiogenesis. Here, I establish in vitro models to study Bartonella-induced blood vessel formation. I found that B. henselae induces long-term endothelial survival and tubular differentiation within type I collagen matrix.

* Mailing address: Department of Pathology, Division of Cancer Biology and Angiogenesis, Beth Israel Deaconess Medical Center, 330 Brookline Ave., Yamins 309, Boston, MA 02215. Phone: (617) 667-3577. Fax: (617) 667-4533. E-mail: jekirby{at}bidmc.harvard.edu.

Editor: J. B. Bliska

Infection and Immunity, December 2004, p. 7315-7317, Vol. 72, No. 12
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.12.7315-7317.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • McCord, A. M., Resto-Ruiz, S. I., Anderson, B. E. (2006). Autocrine Role for Interleukin-8 in Bartonella henselae-Induced Angiogenesis. Infect. Immun. 74: 5185-5190 [Abstract] [Full Text]  


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