This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Stork, M. Articles by Crosa, J. H. Search for Related Content PubMed PubMed Citation Articles by Stork, M. Articles by Crosa, J. H.

 Previous Article  |  Next Article 

Infection and Immunity, December 2004, p. 7326-7329, Vol. 72, No. 12
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.12.7326-7329.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Two tonB Systems Function in Iron Transport in Vibrio anguillarum, but Only One Is Essential for Virulence

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon,¹ Departamento de Microbioloxia e Parasitoloxia, Universidade de Santiago de Compostela, Instituto de Acuicultura, Campus Sur, Santiago de Compostela, Galicia, Spain²

Received 15 July 2004/ Returned for modification 13 August 2004/ Accepted 30 August 2004

We have identified two functional tonB systems in the marine fish pathogen Vibrio anguillarum, tonB1 and tonB2. Each of the tonB genes is transcribed in an operon with the cognate exbB and exbD genes in response to iron limitation. Only tonB2 is essential for transport of ferric anguibactin and virulence.

Editor: J. T. Barbieri

This article has been cited by other articles:

• Alice, A. F., Naka, H., Crosa, J. H. (2008). Global Gene Expression as a Function of the Iron Status of the Bacterial Cell: Influence of Differentially Expressed Genes in the Virulence of the Human Pathogen Vibrio vulnificus. Infect. Immun. 76: 4019-4037 [Abstract] [Full Text]  
• Alvarez, B., Alvarez, J., Menendez, A., Guijarro, J. A. (2008). A mutant in one of two exbD loci of a TonB system in Flavobacterium psychrophilum shows attenuated virulence and confers protection against cold water disease. Microbiology 154: 1144-1151 [Abstract] [Full Text]  
• Benevides-Matos, N., Wandersman, C., Biville, F. (2008). HasB, the Serratia marcescens TonB Paralog, Is Specific to HasR. J. Bacteriol. 190: 21-27 [Abstract] [Full Text]  
• Stork, M., Otto, B. R., Crosa, J. H. (2007). A Novel Protein, TtpC, Is a Required Component of the TonB2 Complex for Specific Iron Transport in the Pathogens Vibrio anguillarum and Vibrio cholerae. J. Bacteriol. 189: 1803-1815 [Abstract] [Full Text]  
• Lopez, C. S., Alice, A. F., Chakraborty, R., Crosa, J. H. (2007). Identification of amino acid residues required for ferric-anguibactin transport in the outer-membrane receptor FatA of Vibrio anguillarum. Microbiology 153: 570-584 [Abstract] [Full Text]  
• Osorio, C. R., Juiz-Rio, S., Lemos, M. L. (2006). A siderophore biosynthesis gene cluster from the fish pathogen Photobacterium damselae subsp. piscicida is structurally and functionally related to the Yersinia high-pathogenicity island.. Microbiology 152: 3327-3341 [Abstract] [Full Text]  
• Welch, T. J., Crosa, J. H. (2005). Novel Role of the Lipopolysaccharide O1 Side Chain in Ferric Siderophore Transport and Virulence of Vibrio anguillarum. Infect. Immun. 73: 5864-5872 [Abstract] [Full Text]