This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kim, H.
Right arrow Articles by Marquis, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kim, H.
Right arrow Articles by Marquis, H.

 Previous Article  |  Next Article 

Infection and Immunity, December 2004, p. 7374-7378, Vol. 72, No. 12
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.12.7374-7378.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Listeria monocytogenes {sigma}B Contributes to Invasion of Human Intestinal Epithelial Cells

Heesun Kim,1 Kathryn J. Boor,1 and Hélène Marquis2*

Department of Food Science,1 Department of Microbiology and Immunology, Cornell University, Ithaca, New York2

Received 20 April 2004/ Returned for modification 18 June 2004/ Accepted 24 August 2004

The role of {sigma}B in Listeria monocytogenes infection of human intestinal epithelial cells was investigated. Invasion defects associated with loss of {sigma}B paralleled those of a {Delta}inlA strain independently of the {sigma}B-dependent P2prfA promoter. Concomitantly, amounts of inlA transcript and InlA protein were significantly decreased in the {Delta}sigB strain.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, VMC 5-169, Cornell University, Ithaca, NY 14853. Phone: (607) 253-3273. Fax: (607) 253-3384. E-mail: hm72{at}cornell.edu.

Editor: V. J. DiRita

Infection and Immunity, December 2004, p. 7374-7378, Vol. 72, No. 12
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.12.7374-7378.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Roberts, A. J., Williams, S. K., Wiedmann, M., Nightingale, K. K. (2009). Some Listeria monocytogenes Outbreak Strains Demonstrate Significantly Reduced Invasion, inlA Transcript Levels, and Swarming Motility In Vitro. Appl. Environ. Microbiol. 75: 5647-5658 [Abstract] [Full Text]  
  • Ollinger, J., Bowen, B., Wiedmann, M., Boor, K. J., Bergholz, T. M. (2009). Listeria monocytogenes {sigma}B Modulates PrfA-Mediated Virulence Factor Expression. Infect. Immun. 77: 2113-2124 [Abstract] [Full Text]  
  • Van Stelten, A., Nightingale, K. K. (2008). Development and Implementation of a Multiplex Single-Nucleotide Polymorphism Genotyping Assay for Detection of Virulence-Attenuating Mutations in the Listeria monocytogenes Virulence-Associated Gene inlA. Appl. Environ. Microbiol. 74: 7365-7375 [Abstract] [Full Text]  
  • Abram, F., Starr, E., Karatzas, K. A. G., Matlawska-Wasowska, K., Boyd, A., Wiedmann, M., Boor, K. J., Connally, D., O'Byrne, C. P. (2008). Identification of Components of the Sigma B Regulon in Listeria monocytogenes That Contribute to Acid and Salt Tolerance. Appl. Environ. Microbiol. 74: 6848-6858 [Abstract] [Full Text]  
  • Nielsen, J. S., Olsen, A. S., Bonde, M., Valentin-Hansen, P., Kallipolitis, B. H. (2008). Identification of a {sigma}B-Dependent Small Noncoding RNA in Listeria monocytogenes. J. Bacteriol. 190: 6264-6270 [Abstract] [Full Text]  
  • Abram, F., Su, W.-L., Wiedmann, M., Boor, K. J., Coote, P., Botting, C., Karatzas, K. A. G., O'Byrne, C. P. (2008). Proteomic Analyses of a Listeria monocytogenes Mutant Lacking {sigma}B Identify New Components of the {sigma}B Regulon and Highlight a Role for {sigma}B in the Utilization of Glycerol. Appl. Environ. Microbiol. 74: 594-604 [Abstract] [Full Text]  
  • Raengpradub, S., Wiedmann, M., Boor, K. J. (2008). Comparative Analysis of the {sigma}B-Dependent Stress Responses in Listeria monocytogenes and Listeria innocua Strains Exposed to Selected Stress Conditions. Appl. Environ. Microbiol. 74: 158-171 [Abstract] [Full Text]  
  • Hu, Y., Raengpradub, S., Schwab, U., Loss, C., Orsi, R. H., Wiedmann, M., Boor, K. J. (2007). Phenotypic and Transcriptomic Analyses Demonstrate Interactions between the Transcriptional Regulators CtsR and Sigma B in Listeria monocytogenes. Appl. Environ. Microbiol. 73: 7967-7980 [Abstract] [Full Text]  
  • Hu, Y., Oliver, H. F., Raengpradub, S., Palmer, M. E., Orsi, R. H., Wiedmann, M., Boor, K. J. (2007). Transcriptomic and Phenotypic Analyses Suggest a Network between the Transcriptional Regulators HrcA and {sigma}B in Listeria monocytogenes. Appl. Environ. Microbiol. 73: 7981-7991 [Abstract] [Full Text]  
  • McGann, P., Ivanek, R., Wiedmann, M., Boor, K. J. (2007). Temperature-Dependent Expression of Listeria monocytogenes Internalin and Internalin-Like Genes Suggests Functional Diversity of These Proteins among the Listeriae. Appl. Environ. Microbiol. 73: 2806-2814 [Abstract] [Full Text]  
  • McGann, P., Wiedmann, M., Boor, K. J. (2007). The Alternative Sigma Factor {sigma}B and the Virulence Gene Regulator PrfA Both Regulate Transcription of Listeria monocytogenes Internalins. Appl. Environ. Microbiol. 73: 2919-2930 [Abstract] [Full Text]  
  • Chaturongakul, S., Boor, K. J. (2006). {sigma}B Activation under Environmental and Energy Stress Conditions in Listeria monocytogenes. Appl. Environ. Microbiol. 72: 5197-5203 [Abstract] [Full Text]  
  • Garner, M. R., James, K. E., Callahan, M. C., Wiedmann, M., Boor, K. J. (2006). Exposure to Salt and Organic Acids Increases the Ability of Listeria monocytogenes To Invade Caco-2 Cells but Decreases Its Ability To Survive Gastric Stress. Appl. Environ. Microbiol. 72: 5384-5395 [Abstract] [Full Text]  
  • Kazmierczak, M. J., Wiedmann, M., Boor, K. J. (2006). Contributions of Listeria monocytogenes {sigma}B and PrfA to expression of virulence and stress response genes during extra- and intracellular growth. Microbiology 152: 1827-1838 [Abstract] [Full Text]  
  • Gray, M. J., Freitag, N. E., Boor, K. J. (2006). How the Bacterial Pathogen Listeria monocytogenes Mediates the Switch from Environmental Dr. Jekyll to Pathogenic Mr. Hyde.. Infect. Immun. 74: 2505-2512 [Full Text]  
  • Garner, M. R., Njaa, B. L., Wiedmann, M., Boor, K. J. (2006). Sigma B Contributes to Listeria monocytogenes Gastrointestinal Infection but Not to Systemic Spread in the Guinea Pig Infection Model. Infect. Immun. 74: 876-886 [Abstract] [Full Text]  
  • Kazmierczak, M. J., Wiedmann, M., Boor, K. J. (2005). Alternative Sigma Factors and Their Roles in Bacterial Virulence. Microbiol. Mol. Biol. Rev. 69: 527-543 [Abstract] [Full Text]  
  • Nightingale, K. K., Windham, K., Martin, K. E., Yeung, M., Wiedmann, M. (2005). Select Listeria monocytogenes Subtypes Commonly Found in Foods Carry Distinct Nonsense Mutations in inlA, Leading to Expression of Truncated and Secreted Internalin A, and Are Associated with a Reduced Invasion Phenotype for Human Intestinal Epithelial Cells. Appl. Environ. Microbiol. 71: 8764-8772 [Abstract] [Full Text]  
  • Kim, H., Marquis, H., Boor, K. J. (2005). {sigma}B contributes to Listeria monocytogenes invasion by controlling expression of inlA and inlB. Microbiology 151: 3215-3222 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»