This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Dong, Y.
Right arrow Articles by Bushkin, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Dong, Y.
Right arrow Articles by Bushkin, Y.

 Previous Article  |  Next Article 

Infection and Immunity, April 2004, p. 2412-2415, Vol. 72, No. 4
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.4.2412-2415.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

HLA-A2-Restricted CD8+-Cytotoxic-T-Cell Responses to Novel Epitopes in Mycobacterium tuberculosis Superoxide Dismutase, Alanine Dehydrogenase, and Glutamine Synthetase

Yuzhi Dong,1 Sandra Demaria,2 Xuming Sun,1 Fabio R. Santori,2 Bill M. Jesdale,3 Anne S. De Groot,3 William N. Rom,2 and Yuri Bushkin1*

Laboratory of Molecular Immunology, Public Health Research Institute, Newark, New Jersey 07103,1 New York University School of Medicine, New York, New York 10016,2 Brown University School of Medicine, Providence, Rhode Island 029123

Received 21 July 2003/ Returned for modification 20 October 2003/ Accepted 16 January 2004

Major histocompatibility complex class I-restricted CD8+ cytotoxic T lymphocytes (CTL) are implicated in protective Th1 immunity to Mycobacterium tuberculosis infection. We report the identification of three novel HLA-A*0201-restricted CTL epitopes within mycobacterial superoxide dismutase (SodA), L-alanine dehydrogenase (AlaDH), and L-glutamine synthetase (GlnS) proteins.


* Corresponding author. Mailing address: Laboratory of Molecular Immunology, Public Health Research Institute, 225 Warren Street, Newark, NJ 07103. Phone: (973) 854-3350. Fax: (973) 854-3101. E-mail: yuri{at}phri.org.

Editor: S. H. E. Kaufmann


Infection and Immunity, April 2004, p. 2412-2415, Vol. 72, No. 4
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.4.2412-2415.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:

  • Schulte, C., Arenskotter, M., Berekaa, M. M., Arenskotter, Q., Priefert, H., Steinbuchel, A. (2008). Possible Involvement of an Extracellular Superoxide Dismutase (SodA) as a Radical Scavenger in Poly(cis-1,4-Isoprene) Degradation. Appl. Environ. Microbiol. 74: 7643-7653 [Abstract] [Full Text]  
  • Aoshi, T., Nagata, T., Suzuki, M., Uchijima, M., Hashimoto, D., Rafiei, A., Suda, T., Chida, K., Koide, Y. (2008). Identification of an HLA-A*0201-Restricted T-Cell Epitope on the MPT51 Protein, a Major Secreted Protein Derived from Mycobacterium tuberculosis, by MPT51 Overlapping Peptide Screening. Infect. Immun. 76: 1565-1571 [Abstract] [Full Text]