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Infection and Immunity, September 2004, p. 5433-5438, Vol. 72, No. 9
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.9.5433-5438.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Transcriptome Analysis of Pseudomonas aeruginosa after Interaction with Human Airway Epithelial Cells

Anders Frisk,1 Jill R. Schurr,2 Guoshun Wang,3 Donna C. Bertucci,3 Luis Marrero,4 Sung Hei Hwang,5 Daniel J. Hassett,5 and Michael J. Schurr1*

Department of Microbiology and Immunology, Program in Molecular Pathogenesis and Immunity, Louisiana Center for Lung Biology and Immunotherapy, Tulane University Health Sciences Center,1 Department of Genetics,2 Gene Therapy Program,3 Morphology and Imaging Core, Louisiana State University Health Sciences Center, New Orleans, Louisiana,4 Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio5

Received 11 February 2004/ Returned for modification 21 April 2004/ Accepted 14 June 2004

The transcriptional profile of Pseudomonas aeruginosa after interactions with primary normal human airway epithelial cells was determined using Affymetrix GeneChip technology. Gene expression profiles indicated that various genes involved in phosphate acquisition and iron scavenging were differentially regulated.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, Program in Molecular Pathogenesis and Immunity, Louisiana Center for Lung Biology and Immunotherapy, Tulane University Health Sciences Center, New Orleans, LA 70112-2699. Phone: (504) 988-4607. Fax: (504) 588-5144. E-mail: mschurr{at}tulane.edu.

Editor: V. J. DiRita

Infection and Immunity, September 2004, p. 5433-5438, Vol. 72, No. 9
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.9.5433-5438.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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