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Infection and Immunity, September 2004, p. 5439-5445, Vol. 72, No. 9
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.9.5439-5445.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Microarray Analysis of Aeromonas hydrophila Cytotoxic Enterotoxin-Treated Murine Primary Macrophages

C. L. Galindo, A. A. Fadl, J. Sha, and A. K. Chopra*

Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas 77555-1070

Received 17 March 2004/ Returned for modification 4 May 2004/ Accepted 14 May 2004

We performed microarray analyses of murine peritoneal macrophages to examine cellular transcriptional responses to a cytotoxic enterotoxin of Aeromonas hydrophila. While 66% of altered genes were common to both primary macrophages and the murine macrophage cell line RAW 264.7, Act caused expression changes of 28 genes specifically in murine peritoneal macrophages.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, Medical Research Building, 301 University Boulevard, University of Texas Medical Branch, Galveston, TX 77555-1070. Phone: (409) 747-0578. Fax: (409) 747-6869. E-mail: achopra{at}utmb.edu.

Editor: J. T. Barbieri

Infection and Immunity, September 2004, p. 5439-5445, Vol. 72, No. 9
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.9.5439-5445.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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