Clinical Research Group, Department of Dermatology, Charité University Medicine Berlin, Humboldt University, D-10089 Berlin, Germany,1 Indian Institute of Chemical Biology, Jadavpur, Calcutta 700032, India,2 Kala-Azar Medical Research Center, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India3
Received 20 August 2004/ Returned for modification 20 November 2004/ Accepted 4 July 2005
Sera of kala-azar patients from Bihar, India, were used to identify Leishmania donovani antigens encoded by a phage expression library. Ten antigens were identified, five of which have not been described as leishmania antigens before. The antigens specifically react with sera of leishmania-infected patients but not of toxoplasma- or plasmodium-infected patients.
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