This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Jordan, D. M. Articles by Moon, H. W. Search for Related Content PubMed PubMed Citation Articles by Jordan, D. M. Articles by Moon, H. W.

Colonization of Gnotobiotic Piglets by a luxS Mutant Strain of Escherichia coli O157:H7

Dianna M. Jordan,^1* Vanessa Sperandio,^2, James B. Kaper,² Evelyn A. Dean-Nystrom,³ and Harley W. Moon¹

Department of Veterinary Pathology, Iowa State University,¹ Pre-Harvest Food Safety and Enteric Disease Research Unit, National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa,³ Center for Vaccine Development and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland²

Received 12 July 2004/ Returned for modification 20 August 2004/ Accepted 7 October 2004

Gnotobiotic piglets inoculated with Escherichia coli O157:H7, its luxS mutant derivative, or nonpathogenic E. coli were evaluated for attaching and effacing lesions. Although no differences in clinical symptoms were seen between pigs inoculated with the parent and those inoculated with the luxS mutant, the luxS mutant-inoculated pigs had a lower frequency of attaching and effacing lesions in the spiral colon than parent strain-inoculated pigs.

Editor: J. B. Bliska

Present address: Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9048.

This article has been cited by other articles:

• Girard, F., Oswald, I. P., Taranu, I., Helie, P., Appleyard, G. D., Harel, J., Fairbrother, J. M. (2005). Host Immune Status Influences the Development of Attaching and Effacing Lesions in Weaned Pigs. Infect. Immun. 73: 5514-5523 [Abstract] [Full Text]