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Infection and Immunity, August 2005, p. 5194-5197, Vol. 73, No. 8
0019-9567/05/$08.00+0     doi:10.1128/IAI.73.8.5194-5197.2005

Intracellular Survival of Campylobacter jejuni in Human Monocytic Cells and Induction of Apoptotic Death by Cytholethal Distending Toxin

Thomas E. Hickey, Gary Majam, and Patricia Guerry*

Enteric Diseases Department, Naval Medical Research Center, Silver Spring, Maryland 20910

Received 13 December 2004/ Returned for modification 21 February 2005/ Accepted 30 March 2005

Campylobacter jejuni 81-176 is capable of extensive replication within human monocytic cell vacuoles and induces apoptotic death via cytolethal distending toxin.

* Corresponding author; Mailing address: Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910. Phone: (301) 319-7662. Fax: (301) 319-7679. E-mail: guerryp{at}nmrc.navy.mil.

Editor: J. T. Barbieri

Infection and Immunity, August 2005, p. 5194-5197, Vol. 73, No. 8
0019-9567/05/$08.00+0     doi:10.1128/IAI.73.8.5194-5197.2005




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