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Infection and Immunity, October 2006, p. 6011-6015, Vol. 74, No. 10
0019-9567/06/$08.00+0     doi:10.1128/IAI.00797-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Porphyromonas gingivalis Minor Fimbriae Are Required for Cell-Cell Interactions

School of Dentistry, Meharry Medical College, Nashville, Tennessee

Received 17 May 2006/ Returned for modification 20 June 2006/ Accepted 28 July 2006

Two distinctive types of fimbriae have been identified in Porphyromonas gingivalis. In this report, we demonstrate that minor fimbriae are involved in P. gingivalis autoaggregation and colonization. A mutant with a deficiency in minor fimbriae can bind to a saliva-coated surface but does not form microcolonies as the wild-type strain does.

Editor: J. B. Bliska

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