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Infection and Immunity, February 2006, p. 1373-1375, Vol. 74, No. 2
0019-9567/06/$08.00+0     doi:10.1128/IAI.74.2.1373-1375.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Reservoir Competency of Goats for the Ap-Variant 1 Strain of Anaplasma phagocytophilum

Robert F. Massung,1* Thomas N. Mather,2 and Michael L. Levin1

Viral and Rickettsial Zoonoses Branch, Division of Viral and Rickettsial Diseases, CDC, Atlanta, Georgia,1 Center for Vector-Borne Disease, University of Rhode Island, Kingston, Rhode Island2

Received 2 September 2005/ Returned for modification 8 October 2005/ Accepted 8 November 2005

Field-collected ticks were used to infect goats with either Ap-ha, a strain associated with human disease, or a variant strain, Ap-Variant 1, of Anaplasma phagocytophilum. Goats were shown to be competent as a reservoir for Ap-Variant 1, and challenge and immunosuppression studies were used to further examine infection in the goat model.

* Corresponding author. Mailing address: Centers for Disease Control and Prevention, 1600 Clifton Rd., MS G-13, Atlanta, GA 30333. Phone: (404) 639-1082. Fax: (404) 639-4436. E-mail: rfm2{at}cdc.gov.

Editor: J. T. Barbieri

Infection and Immunity, February 2006, p. 1373-1375, Vol. 74, No. 2
0019-9567/06/$08.00+0     doi:10.1128/IAI.74.2.1373-1375.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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