This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lawlor, M. S.
Right arrow Articles by Miller, V. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lawlor, M. S.
Right arrow Articles by Miller, V. L.

 Previous Article  |  Next Article 

Infection and Immunity, September 2006, p. 5402-5407, Vol. 74, No. 9
0019-9567/06/$08.00+0     doi:10.1128/IAI.00244-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Comparison of the Host Responses to Wild-Type and cpsB Mutant Klebsiella pneumoniae Infections

Matthew S. Lawlor,1 Scott A. Handley,1 and Virginia L. Miller1,2*

Departments of Molecular Microbiology,1 Pediatrics, Washington University School of Medicine, St. Louis, Missouri 631102

Received 14 February 2006/ Returned for modification 28 March 2006/ Accepted 14 June 2006

Previously, we established an intranasal mouse model of Klebsiella pneumoniae infection and validated its utility using a highly virulent wild-type strain and an avirulent capsular polysaccharide mutant. In the present study we compare the host responses to both infections by examining cytokine production, cellular infiltration, pulmonary histology, and intranasal immunization.

* Corresponding author. Mailing address: Department of Molecular Microbiology, Campus Box 8230, 660 S. Euclid Ave., St. Louis, MO 63110. Phone: (314) 286-2891. Fax: (314) 286-2896. E-mail: virginia{at}borcim.wustl.edu.

Editor: J. B. Bliska

Infection and Immunity, September 2006, p. 5402-5407, Vol. 74, No. 9
0019-9567/06/$08.00+0     doi:10.1128/IAI.00244-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Tu, Y.-C., Lu, M.-C., Chiang, M.-K., Huang, S.-P., Peng, H.-L., Chang, H.-Y., Jan, M.-S., Lai, Y.-C. (2009). Genetic Requirements for Klebsiella pneumoniae-Induced Liver Abscess in an Oral Infection Model. Infect. Immun. 77: 2657-2671 [Abstract] [Full Text]  
  • Regueiro, V., Moranta, D., Campos, M. A., Margareto, J., Garmendia, J., Bengoechea, J. A. (2009). Klebsiella pneumoniae Increases the Levels of Toll-Like Receptors 2 and 4 in Human Airway Epithelial Cells. Infect. Immun. 77: 714-724 [Abstract] [Full Text]  
  • Bubeck, S. S., Cantwell, A. M., Dube, P. H. (2007). Delayed Inflammatory Response to Primary Pneumonic Plague Occurs in Both Outbred and Inbred Mice. Infect. Immun. 75: 697-705 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»