Infection and Immunity, December 2007, p. 6008-6012, Vol. 75, No. 12
0019-9567/07/$08.00+0 doi:10.1128/IAI.01995-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322,1 Laboratories of Bacterial Pathogenesis, VA Medical Center, Decatur, Georgia 300332
Received 20 December 2006/ Returned for modification 16 March 2007/ Accepted 26 September 2007
A 2.9-kilobase pair locus in Neisseria meningitidis was identified as containing transcriptionally linked open reading frames encoding TolC- and HlyD-like proteins. Although the meningococcal TolC protein was required for extracellular production of the repeats-in-toxin (RTX) FrpC toxin, it could not functionally replace the MtrE protein as the outer membrane protein channel for drug export by the MtrC-MtrD-MtrE efflux pump.
Published ahead of print on 8 October 2007.
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