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Infection and Immunity, March 2007, p. 1512-1516, Vol. 75, No. 3
0019-9567/07/$08.00+0     doi:10.1128/IAI.00942-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Expression of the Yersinia enterocolitica pYV-Encoded Type III Secretion System Is Modulated by Lipopolysaccharide O-Antigen Status{triangledown}

Camino Pérez-Gutiérrez,1,{dagger} Catalina M. Llompart,1,{dagger} Mikael Skurnik,2 and José A. Bengoechea1*

Unidad de Investigación and Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS), Hospital Universitario Son Dureta, Palma de Mallorca, Spain,1 Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, and Helsinki University Central Hospital Laboratory Diagnostics, Helsinki, Finland2

Received 13 June 2006/ Returned for modification 24 July 2006/ Accepted 11 December 2006

We show that the expression of a Yersinia enterocolitica O:8 pYV-encoded type III secretion system was altered in a rough mutant (YeO8-R) due to elevated levels of FlhDC. H-NS might underlie flhDC upregulation in YeO8-R, and the data suggest a relationship between the absence of O antigen and the expression of H-NS.

* Corresponding author. Mailing address: Fundació Caubet-CIMERA Illes Balears, Recinto Hospital Joan March, Carretera Soller km 12, 07110 Bunyola, Spain. Phone: 34 971 011780. Fax: 34 971 011797. E-mail: bengoechea{at}caubet-cimera.es.

{triangledown} Published ahead of print on 18 December 2006.

Editor: J. B. Bliska

{dagger} C.P.-G. and C.M.L. contributed equally to this work.

Infection and Immunity, March 2007, p. 1512-1516, Vol. 75, No. 3
0019-9567/07/$08.00+0     doi:10.1128/IAI.00942-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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