IAI FigSearch
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Other Versions of this Article:
IAI.01725-06v1
75/3/1517    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tilly, K.
Right arrow Articles by Rosa, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tilly, K.
Right arrow Articles by Rosa, P.
Infection and Immunity, March 2007, p. 1517-1519, Vol. 75, No. 3
0019-9567/07/$08.00+0     doi:10.1128/IAI.01725-06

Rapid Clearance of Lyme Disease Spirochetes Lacking OspC from Skin{triangledown}

Kit Tilly,* Aaron Bestor, Mollie W. Jewett, and Patricia Rosa

Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840

Received 27 October 2006/ Returned for modification 14 November 2006/ Accepted 29 November 2006

We previously demonstrated that Borrelia burgdorferi requires OspC to colonize a mammalian host. To delineate this requirement, we analyzed the clearance of ospC mutant spirochetes and found that they were eliminated within 48 h. We conclude that B. burgdorferi uses OspC to resist innate host defenses immediately after transmission.


* Corresponding author. Mailing address: 903 S. 4th Street, Hamilton, MT 59840. Phone: (406) 363-9239. Fax: (406) 363-9394. E-mail: ktilly{at}niaid.nih.gov.

{triangledown} Published ahead of print on 11 December 2006.

Editor: R. P. Morrison


Infection and Immunity, March 2007, p. 1517-1519, Vol. 75, No. 3
0019-9567/07/$08.00+0     doi:10.1128/IAI.01725-06




This article has been cited by other articles:




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
J. Bacteriol. J. Virol. Eukaryot. Cell
Microbiol. Mol. Biol. Rev. Clin. Vaccine Immunol. All ASM Journals

Copyright © 2007 by the American Society for Microbiology. All rights reserved.