IAI FigSearch
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Other Versions of this Article:
IAI.01938-06v1
75/3/1537    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fozo, E. M.
Right arrow Articles by Quivey, R. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fozo, E. M.
Right arrow Articles by Quivey, R. G., Jr.

 Previous Article  |  Next Article 

Infection and Immunity, March 2007, p. 1537-1539, Vol. 75, No. 3
0019-9567/07/$08.00+0     doi:10.1128/IAI.01938-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Role of Unsaturated Fatty Acid Biosynthesis in Virulence of Streptococcus mutans{triangledown}

Elizabeth M. Fozo,1,{dagger} Kathy Scott-Anne,2 Hyun Koo,2,3 and Robert G. Quivey Jr.1,2*

Department of Microbiology and Immunology,1 Center for Oral Biology, Aab Institute for Biomedical Sciences,2 Eastman Dental Center, University of Rochester School of Medicine and Dentistry, Rochester, New York 146423

Received 8 December 2006/ Accepted 20 December 2006

An insertionally inactivated fabM strain of Streptococcus mutans does not produce unsaturated membrane fatty acids and is acid sensitive (E. M. Fozo and R. G. Quivey, Jr., J. Bacteriol. 186:4152-4158, 2004). In this study, the strain was shown to be poorly transmissible from host to host. Animals directly infected with the fabM strain exhibited fewer and less severe carious lesions than those observed in the wild-type strain.

* Corresponding author. Mailing address: Center for Oral Biology, Box 611, 601 Elmwood Avenue, Rochester, NY 14642. Phone: (585) 275-0382. Fax: (585) 276-0190. E-mail: Robert_Quivey{at}urmc.rochester.edu.

{triangledown} Published ahead of print on 12 January 2007.

Editor: V. J. DiRita

{dagger} Present address: National Institute for Child Health and Human Disease, National Institutes of Health, Bethesda, MD.

Infection and Immunity, March 2007, p. 1537-1539, Vol. 75, No. 3
0019-9567/07/$08.00+0     doi:10.1128/IAI.01938-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
J. Bacteriol. J. Virol. Eukaryot. Cell
Microbiol. Mol. Biol. Rev. Clin. Vaccine Immunol. All ASM Journals

Copyright © 2007 by the American Society for Microbiology. All rights reserved.