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Infection and Immunity, September 2007, p. 4664-4669, Vol. 75, No. 9
0019-9567/07/$08.00+0     doi:10.1128/IAI.00972-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Contribution of a Novel Gene, rpeA, Encoding a Putative Autotransporter Adhesin to Intestinal Colonization by Rabbit-Specific Enteropathogenic Escherichia coli{triangledown}

Denisse L. Leyton,1 Louise M. Adams,2 Michelle Kelly,1 Joan Sloan,1 Marija Tauschek,2 Roy M. Robins-Browne,2,3 and Elizabeth L. Hartland1,3*

Australian Bacterial Pathogenesis Program, Department of Microbiology, Monash University, Victoria 3800,1 Australian Bacterial Pathogenesis Program, Department of Microbiology and Immunology, University of Melbourne, Victoria 3010,2 Microbiological Research Unit, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville 3052, Australia3

Received 16 June 2006/ Returned for modification 24 July 2006/ Accepted 26 June 2007

Rabbit-specific enteropathogenic Escherichia coli (REPEC) is an attaching and effacing pathogen of young rabbits. Using signature-tagged mutagenesis, we identified several known colonization factors of REPEC as well as a gene predicted to encode a novel autotransporter protein. This novel gene was termed rpeA for REPEC plasmid-encoded autotransporter.

* Corresponding author. Mailing address: Department of Microbiology, Monash University, Victoria 3800, Australia. Phone: (61) 3 9905 4323. Fax: (61) 3 9905 4811. E-mail: Liz.Hartland{at}med.monash.edu.au

{triangledown} Published ahead of print on 9 July 2007.

Editor: J. B. Bliska

Infection and Immunity, September 2007, p. 4664-4669, Vol. 75, No. 9
0019-9567/07/$08.00+0     doi:10.1128/IAI.00972-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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