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Infect Immun. 1973 October; 8(4): 677-678
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Virulence Differences in Mice of Type A and B Histoplasma capsulatum Yeasts Grown in Continuous Light and Total Darkness

^a Department of Microbiology, Harvard School of Public Health, Boston, Massachusetts 02115

ABSTRACT

Type B yeasts were more virulent for mice than type A under most experimental conditions. Mice infected with type B yeasts grown in the light lived significantly longer than those with type B yeasts grown in the dark. Virulence differences of type A yeasts grown in continuous fluorescent light versus total darkness were not statistically significant.

¹ Present address: Southern Illinois University School of Medicine, P.O. Box 3926, Springfield, Ill. 62708.

² Present address: Department of Biology, Simmons College, 300 The Fenway, Boston, Mass. 02115.

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