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Infect Immun. 1977 December; 18(3): 775-779

Vero response to a cytotoxin of Escherichia coli.

J Konowalchuk, J I Speirs and S Stavric

ABSTRACT

A cytotoxin was found in culture filtrates of a number of Escherichia coli strains that differed from the known heat-stable and heat-labile enterotoxins of E. coli. It was cytotoxic for Vero but not for Y-1 or CHO cells, and its effect on Vero was distinctly different from that of heat-labile enterotoxin. It was labile to heat and antigenically different from heat-labile enterotoxin, and membrane filtration indicated a molecular weight of 10,000 to 30,000.

Infect Immun. 1977 December; 18(3): 775-779




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