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Infect Immun. 1972 September; 6(3): 277-281
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Human Immunoglobulin Specificity After Group B Arbovirus Infections

¹ Department of Virus Diseases, Walter Reed Army Institute of Research, Washington, D.C. 20012

ABSTRACT

Sera obtained during a dengue-2 epidemic from individuals with primary or secondary group B arbovirus infections contained cross-reactive antibody against several viruses in this group. Hemagglutination-inhibition antibody titers of the immunoglobulin M fractions from these sera revealed a rise in antibody specific for dengue-2. The acute and convalescent sera in over half of the secondary infection group also had low-level unchanging immunoglobulin M antibody titers to yellow fever which implicated yellow fever immunization as the primary infection.