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Infection and Immunity, November 1998, p. 5576-5579, Vol. 66, No. 11
Department of Microbiology, Colorado State
University, Fort Collins, Colorado 80523,1
and
Institut Pasteur, Paris, France2
Received 19 December 1997/Returned for modification 29 January
1998/Accepted 26 June 1998
During DNA sequence analysis of cosmid L373 from the
Mycobacterium leprae genome, an open reading frame of 1.4 kb encoding a protein with some homology to the immunodominant 34-kDa
protein of Mycobacterium paratuberculosis, but lacking
significant serological activity, was detected. The DNA sequence
predicted a signal peptide with a modified lipoprotein consensus
sequence, but the protein proved to be devoid of lipid attachment.
0019-9567/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
Characterization of a 34-Kilodalton Protein of
Mycobacterium leprae That Is Isologous to the
Immunodominant 34-Kilodalton Antigen of Mycobacterium
paratuberculosis

*
Corresponding author. Mailing address: Department of
Microbiology, Colorado State University, Fort Collins, CO 80523. Phone: (970) 491-6700. Fax: (970) 491-1815. E-mail:
pbrennan{at}cvmbs.colostate.edu.
Permanent address: Department of Microbiology, Yonsei University
College of Medicine, Seoul, Republic of Korea.
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