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Infect Immun, March 1998, p. 1261-1264, Vol. 66, No. 3
0019-9567/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Identification of Epitopes of Fibronectin Attachment Protein (FAP-A) of Mycobacterium avium Which Stimulate Strong T-Cell Responses in Mice

Matthew A. Holsti,1 Jeffrey S. Schorey,2 Eric J. Brown,2,3 and Paul M. Allen1,*

Center for Immunology and Department of Pathology,1 Department of Internal Medicine,2 and Department of Molecular Microbiology,3 Washington University School of Medicine, St. Louis, Missouri 63110

Received 12 June 1997/Returned for modification 8 July 1997/Accepted 16 December 1997

The T-cell response to fibronectin attachment protein (FAP-A) in BALB/c and B10.BR mice was examined. Both strains developed strong T-cell responses to FAP-A, directed to single, unique epitopes. T cells from mice infected with Mycobacterium avium responded to FAP-A, suggesting a possible role in a protective immune response.

* Corresponding author. Mailing address: Department of Pathology, Washington University School of Medicine, Campus Box 8118, 660 South Euclid Avenue, St. Louis, MO 63110. Phone: (314) 362-8758. Fax: (314) 362-8888. E-mail: allen{at}immunology.wustl.edu.




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  • Beatty, W. L., Russell, D. G. (2000). Identification of Mycobacterial Surface Proteins Released into Subcellular Compartments of Infected Macrophages. Infect. Immun. 68: 6997-7002 [Abstract] [Full Text]  


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