This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Donabedian, H.
Right arrow Articles by Boyle, M. D. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Donabedian, H.
Right arrow Articles by Boyle, M. D. P.

 Previous Article  |  Next Article 

Infect Immun, May 1998, p. 2362-2364, Vol. 66, No. 5
0019-9567/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Clot Formation by Group A Streptococci

Haig Donabedian* and Michael D. P. Boyle

Medical College of Ohio, Toledo, Ohio

Received 24 November 1997/Returned for modification 21 January 1998/Accepted 25 February 1998

Group A streptococci of several different M serotypes can cause human plasma to clot in nutrient-poor media. Addition of glucose to the medium prevents clot formation. Once formed, clots are stable for several days and can be lysed on addition of exogenous streptokinase or urokinase. Clot lysis can also be achieved by addition of glucose to a clot containing wild-type group A streptococci but not clots containing an isogenic mutant in which the ska gene was inactivated.

* Corresponding author. Mailing address: Rm 0007-K, 3120 Glendale Avenue, Toledo, OH 43614. Phone: (419) 383-4328. Fax: (419) 383-6244. E-mail: hdonabedian{at}magnum.mco.edu.

Infect Immun, May 1998, p. 2362-2364, Vol. 66, No. 5
0019-9567/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.




Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»