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Infection and Immunity, May 1999, p. 2653-2655, Vol. 67, No. 5
0019-9567/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

In Vitro Adhesion and Platelet Aggregation Properties of Bacteremia-Associated Lactobacilli

Pirkka V. Kirjavainen,1,* Elina M. Tuomola,1 Ross G. Crittenden,2 Arthur C. Ouwehand,1 Derek W. S. Harty,3 Leone F. Morris,2 Hilpi Rautelin,4 Martin J. Playne,2 Diana C. Donohue,5 and Seppo J. Salminen1,5

Department of Biochemistry and Food Chemistry, University of Turku, Turku,1 and Department of Bacteriology and Immunology, University of Helsinki, Helsinki,4 Finland, and Food Science Australia2 and Key Centre for Applied and Nutritional Toxicology, Royal Melbourne Institute of Technology,5 Melbourne, and Institute of Dental Research, Faculty of Dentistry, University of Sydney, Sydney,3 Australia

Received 9 November 1998/Returned for modification 28 January 1999/Accepted 18 February 1999

Eight bacteremia-associated Lactobacillus strains were evaluated in vitro for the ability to adhere to human intestinal mucosa and to aggregate platelets. Adherence varied significantly among the strains, and platelet aggregation was induced by three strains. In conclusion, strong binding ability does not appear to be a prerequisite for the involvement of lactobacilli in bacteremia or to their ability to aggregate platelets.

* Corresponding author. Mailing address: Department of Biochemistry and Food Chemistry, University of Turku, Fin-20014 Turku, Finland. Phone: 358-2-3336894. Fax: 358-2-3336860. E-mail: pirkka.kirjavainen{at}utu.fi.

Infection and Immunity, May 1999, p. 2653-2655, Vol. 67, No. 5
0019-9567/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

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