IAI FigSearch
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Biondo, C.
Right arrow Articles by Teti, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Biondo, C.
Right arrow Articles by Teti, G.

 Previous Article  |  Next Article 

Infection and Immunity, September 2003, p. 5412-5417, Vol. 71, No. 9
0019-9567/03/$08.00+0     DOI: 10.1128/IAI.71.9.5412-5417.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Induction of T Helper Type 1 Responses by a Polysaccharide Deacetylase from Cryptococcus neoformans

Carmelo Biondo, Concetta Beninati, Mauro Bombaci, Luciano Messina, Giuseppe Mancuso, Angelina Midiri, Roberta Galbo, and Giuseppe Teti*

Dipartimento di Patologia e Microbiologia Sperimentale, Facoltà di Medicina e Chirurgia, Università di Messina, I-98125 Messina, Italy

Received 13 December 2002/ Returned for modification 28 January 2003/ Accepted 23 June 2003

A 25-kDa cryptococcal deacetylase (d25) was found here to induce cell proliferation, as well as secretion of interleukin 2 and gamma interferon, but not interleukin 4, in spleen cells from d25-immunized or Cryptococcus neoformans-infected mice. The gamma interferon, but not the interleukin 2, response was required for the protective activities of d25 immunization in a murine cryptococcosis model.

* Corresponding author. Mailing address: Dipartimento di Patologia e Microbiologia Sperimentale, Policlinico Universitario, Via Consolare Valeria, 1 (Gazzi), I-98125 Messina, Italy. Phone: 39 090 221-3311. Fax: 39 090 221-3312. E-mail: teti{at}eniware.it.

Editor: T. R. Kozel

Infection and Immunity, September 2003, p. 5412-5417, Vol. 71, No. 9
0019-9567/03/$08.00+0     DOI: 10.1128/IAI.71.9.5412-5417.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
J. Bacteriol. J. Virol. Eukaryot. Cell
Microbiol. Mol. Biol. Rev. Clin. Vaccine Immunol. All ASM Journals

Copyright © 2003 by the American Society for Microbiology. All rights reserved.