This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Leonard, E. E.
Right arrow Articles by Nachamkin, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Leonard, E. E., II
Right arrow Articles by Nachamkin, I.

 Previous Article  |  Next Article 

Infection and Immunity, February 2004, p. 1199-1203, Vol. 72, No. 2
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.2.1199-1203.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Comparison of Campylobacter jejuni Isolates Implicated in Guillain-Barré Syndrome and Strains That Cause Enteritis by a DNA Microarray

Edward E. Leonard II,1,2,{dagger} Lucy S. Tompkins,1,2 Stanley Falkow,1 and Irving Nachamkin3*

Department of Microbiology and Immunology,1 Division of Infectious Diseases, Stanford University, Stanford, California 94305,2 Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 191043

Received 17 July 2003/ Returned for modification 16 September 2003/ Accepted 14 October 2003

We asked whether Campylobacter jejuni isolated from patients with Guillain-Barré syndrome (GBS) differ from isolates isolated from patients with uncomplicated gastrointestinal infection using DNA microarray analysis. We found that specific GBS genes or regions were not identified, and microarray analysis confirmed significant genomic heterogeneity among the isolates.


* Corresponding author. Mailing address: Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Gates Building, 4th Floor, 3400 Spruce St., Philadelphia, PA 19104-4283. Phone: (215) 662-6651. Fax: (215) 662-6655. E-mail: nachamki{at}mail.med.upenn.edu.

Editor: V. J. DiRita

{dagger} Present address: Infectious Disease Group, Bellevue, WA 98004.


Infection and Immunity, February 2004, p. 1199-1203, Vol. 72, No. 2
0019-9567/04/$08.00+0     DOI: 10.1128/IAI.72.2.1199-1203.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:

  • Igboin, C. O., Griffen, A. L., Leys, E. J. (2009). Porphyromonas gingivalis Strain Diversity. J. Clin. Microbiol. 47: 3073-3081 [Abstract] [Full Text]  
  • Hannon, S. J., Taboada, E. N., Russell, M. L., Allan, B., Waldner, C., Wilson, H. L., Potter, A., Babiuk, L., Townsend, H. G. G. (2009). Genomics-Based Molecular Epidemiology of Campylobacter jejuni Isolates from Feedlot Cattle and from People in Alberta, Canada. J. Clin. Microbiol. 47: 410-420 [Abstract] [Full Text]  
  • Parker, C. T., Gilbert, M., Yuki, N., Endtz, H. P., Mandrell, R. E. (2008). Characterization of Lipooligosaccharide-Biosynthetic Loci of Campylobacter jejuni Reveals New Lipooligosaccharide Classes: Evidence of Mosaic Organizations. J. Bacteriol. 190: 5681-5689 [Abstract] [Full Text]  
  • Muller, J., Meyer, B., Hanel, I., Hotzel, H. (2007). Comparison of lipooligosaccharide biosynthesis genes of Campylobacter jejuni strains with varying abilities to colonize the chicken gut and to invade Caco-2 cells. J Med Microbiol 56: 1589-1594 [Abstract] [Full Text]  
  • Belanger, A. E., Shryock, T. R. (2007). Macrolide-resistant Campylobacter: the meat of the matter. J Antimicrob Chemother 60: 715-723 [Abstract] [Full Text]  
  • Poly, F., Read, T., Tribble, D. R., Baqar, S., Lorenzo, M., Guerry, P. (2007). Genome Sequence of a Clinical Isolate of Campylobacter jejuni from Thailand. Infect. Immun. 75: 3425-3433 [Abstract] [Full Text]  
  • Quinones, B., Parker, C. T., Janda, J. M. Jr., Miller, W. G., Mandrell, R. E. (2007). Detection and Genotyping of Arcobacter and Campylobacter Isolates from Retail Chicken Samples by Use of DNA Oligonucleotide Arrays. Appl. Environ. Microbiol. 73: 3645-3655 [Abstract] [Full Text]  
  • Berger, B., Pridmore, R. D., Barretto, C., Delmas-Julien, F., Schreiber, K., Arigoni, F., Brussow, H. (2007). Similarity and Differences in the Lactobacillus acidophilus Group Identified by Polyphasic Analysis and Comparative Genomics. J. Bacteriol. 189: 1311-1321 [Abstract] [Full Text]  
  • Price, E. P., Huygens, F., Giffard, P. M. (2006). Fingerprinting of Campylobacter jejuni by Using Resolution-Optimized Binary Gene Targets Derived from Comparative Genome Hybridization Studies. Appl. Environ. Microbiol. 72: 7793-7803 [Abstract] [Full Text]  
  • Parker, C. T., Quinones, B., Miller, W. G., Horn, S. T., Mandrell, R. E. (2006). Comparative Genomic Analysis of Campylobacter jejuni Strains Reveals Diversity Due to Genomic Elements Similar to Those Present in C. jejuni Strain RM1221. J. Clin. Microbiol. 44: 4125-4135 [Abstract] [Full Text]  
  • Hofreuter, D., Tsai, J., Watson, R. O., Novik, V., Altman, B., Benitez, M., Clark, C., Perbost, C., Jarvie, T., Du, L., Galan, J. E. (2006). Unique Features of a Highly Pathogenic Campylobacter jejuni Strain.. Infect. Immun. 74: 4694-4707 [Abstract] [Full Text]  
  • Koga, M., Takahashi, M., Masuda, M., Hirata, K., Yuki, N. (2005). Campylobacter gene polymorphism as a determinant of clinical features of Guillain-Barre syndrome. Neurology 65: 1376-1381 [Abstract] [Full Text]  
  • Witney, A. A., Marsden, G. L., Holden, M. T. G., Stabler, R. A., Husain, S. E., Vass, J. K., Butcher, P. D., Hinds, J., Lindsay, J. A. (2005). Design, Validation, and Application of a Seven-Strain Staphylococcus aureus PCR Product Microarray for Comparative Genomics. Appl. Environ. Microbiol. 71: 7504-7514 [Abstract] [Full Text]  
  • Champion, O. L., Gaunt, M. W., Gundogdu, O., Elmi, A., Witney, A. A., Hinds, J., Dorrell, N., Wren, B. W. (2005). Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. Proc. Natl. Acad. Sci. USA 102: 16043-16048 [Abstract] [Full Text]  
  • Parker, C. T., Horn, S. T., Gilbert, M., Miller, W. G., Woodward, D. L., Mandrell, R. E. (2005). Comparison of Campylobacter jejuni Lipooligosaccharide Biosynthesis Loci from a Variety of Sources. J. Clin. Microbiol. 43: 2771-2781 [Abstract] [Full Text]  
  • Poly, F., Threadgill, D., Stintzi, A. (2005). Genomic Diversity in Campylobacter jejuni: Identification of C. jejuni 81-176-Specific Genes. J. Clin. Microbiol. 43: 2330-2338 [Abstract] [Full Text]