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Infection and Immunity, June 2005, p. 3764-3772, Vol. 73, No. 6
0019-9567/05/$08.00+0     doi:10.1128/IAI.73.6.3764-3772.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Effect of Anaerobiosis and Nitrate on Gene Expression in Pseudomonas aeruginosa

M. J. Filiatrault, V. E. Wagner, D. Bushnell, C. G. Haidaris, B. H. Iglewski,* and L. Passador{dagger}

Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642

Received 15 October 2004/ Returned for modification 24 November 2004/ Accepted 2 February 2005

DNA microarrays were used to examine the transcriptional response of Pseudomonas aeruginosa to anaerobiosis and nitrate. In response to anaerobic growth, 691 transcripts were differentially expressed. Comparisons of P. aeruginosa grown aerobically in the presence or the absence of nitrate showed differential expression of greater than 900 transcripts.


* Corresponding author. Mailing address: University of Rochester School of Medicine and Dentistry, Department of Microbiology and Immunology, 601 Elmwood Avenue, Box 672, Rochester, NY 14642. Phone: (585) 275-3402. Fax: (585) 473-9573. E-mail: bigl{at}mail.rochester.edu.

Editor: J. T. Barbieri

{dagger} Present address: Thomson Physicians World, 150 Meadowlands Parkway, Secaucus, NJ 07094.


Infection and Immunity, June 2005, p. 3764-3772, Vol. 73, No. 6
0019-9567/05/$08.00+0     doi:10.1128/IAI.73.6.3764-3772.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.




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