This Article Full Text (PDF) Other Versions of this Article: IAI.00656-06v1 75/6/3183    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Feldmann, F. Articles by Schubert, S. Search for Related Content PubMed PubMed Citation Articles by Feldmann, F. Articles by Schubert, S.

 Previous Article  |  Next Article 

Infect. Immun. doi:10.1128/IAI.00656-06
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

The Salmochelin siderophore receptor IroN contributes to invasion of urothelial cells by extraintestinal pathogenic Escherichia coli in vitro

Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität München, Marchioninistr. 17, 81377 München, Germany

^* To whom correspondence should be addressed. Email: schubert{at}med.uni-muenchen.de.

	Abstract

Extraintestinal pathogenic Escherichia coli (ExPEC) possess several siderophore dependent iron uptake systems. In this study we demonstrate that the salmochelin siderophore receptor IroN is involved in the invasion process of ExPECs into urothelial cells in vitro. Thus, IroN may play a dual role in the establishment of urinary tract infections displaying an iron-uptake receptor as well as an internalization factor.

This article has been cited by other articles:

• Caza, M., Lepine, F., Milot, S., Dozois, C. M. (2008). Specific Roles of the iroBCDEN Genes in Virulence of an Avian Pathogenic Escherichia coli O78 Strain and in Production of Salmochelins. Infect. Immun. 76: 3539-3549 [Abstract] [Full Text]