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Infect. Immun. doi:10.1128/IAI.01955-06
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Amended Description of the Genes for Synthesis of Actinomyces naeslundii T14V Type 1 Fimbriae and Associated Adhesin

Microbiology Branch, US Army Dental and Trauma Research Detachment, Walter Reed Army Institute of Research, Great Lakes, IL 60088, Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research and the Proteomics and Mass Spectrometry Facility, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda MD 20892

^* To whom correspondence should be addressed. Email: kai.leung{at}us.army.mil.

	Abstract

The type 1 fimbriae of Actinomyces naeslundii T14V mediate adhesion of this gram-positive species to the tooth surface. The present findings show that the locus for type 1 fimbriae production in this strain includes three genes, fimQ for a minor fimbrial subunit that appears to be an adhesin, fimP for the major structural subunit and srtC1 for a type 1 fimbriae-specific sortase involved in the assembly of these structures.