Contents: March 2000, Volume 68, Issue 3        Bacterial Infections        Host Response and Inflammation        Fungal and Parasitic Infections        Microbial Immunity and Vaccines        Molecular and Cellular Pathogenesis        Molecular Genomics Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Bacterial Infections:

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Differential Bacterial Survival, Replication, and Apoptosis-Inducing Ability of Salmonella Serovars within Human and Murine Macrophages William R. Schwan, Xiao-Zhe Huang, Lan Hu, and Dennis J. Kopecko Infect. Immun. March 2000 68: 1005-1013; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Allele Substitution of the Streptokinase Gene Reduces the Nephritogenic Capacity of Group A Streptococcal Strain NZ131 Annika Nordstrand, W. Michael McShan, Joseph J. Ferretti, Stig E. Holm, and Mari Norgren Infect. Immun. March 2000 68: 1019-1025; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Eukaryotic Cell Uptake of Heparin-Coated Microspheres: a Model of Host Cell Invasion by Chlamydia trachomatis Richard S. Stephens, Farah S. Fawaz, Kathleen A. Kennedy, Kelly Koshiyama, Barbara Nichols, Christiaan van Ooij, and Joanne N. Engel Infect. Immun. March 2000 68: 1080-1085; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Borrelia burgdorferi Gene Expression In Vivo and Spirochete Pathogenicity Juan Anguita, Swapna Samanta, Beatriz Revilla, Kyoungho Suk, Subrata Das, Stephen W. Barthold, and Erol Fikrig Infect. Immun. March 2000 68: 1222-1230; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of Brucella suis Genes Affecting Intracellular Survival in an In Vitro Human Macrophage Infection Model by Signature-Tagged Transposon Mutagenesis Vincent Foulongne, Giséle Bourg, Chantal Cazevieille, Sylvie Michaux-Charachon, and David O'Callaghan Infect. Immun. March 2000 68: 1297-1303; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Coinvasion of Dentinal Tubules by Porphyromonas gingivalis and Streptococcus gordonii Depends upon Binding Specificity of Streptococcal Antigen I/II Adhesin Robert M. Love, Malcolm D. McMillan, Yoonsuk Park, and Howard F. Jenkinson Infect. Immun. March 2000 68: 1359-1365; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Immunity Reduces Reservoir Host Competence of Peromyscus leucopus for Ehrlichia phagocytophila Michael L. Levin and Durland Fish Infect. Immun. March 2000 68: 1514-1518; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Colonic Bacteria Express an Ulcerative Colitis pANCA-Related Protein Epitope O. Cohavy, D. Bruckner, L. K. Gordon, R. Misra, B. Wei, M. E. Eggena, S. R. Targan, and J. Braun Infect. Immun. March 2000 68: 1542-1548; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Analysis of the F Antigen-Specific papA Alleles of Extraintestinal Pathogenic Escherichia coli Using a Novel Multiplex PCR-Based Assay James R. Johnson, Adam L. Stell, Flemming Scheutz, Timothy T. O'Bryan, Thomas A. Russo, Ulrike B. Carlino, Claudine Fasching, Justine Kavle, Linda Van Dijk, and Wim Gaastra Infect. Immun. March 2000 68: 1587-1599; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Resistance to Experimental Infection with Mycobacterium bovis in Red Deer (Cervus elaphus) Colin G. Mackintosh, Tariq Qureshi, Ken Waldrup, Robert E. Labes, Ken G. Dodds, and J. Frank T. Griffin Infect. Immun. March 2000 68: 1620-1625; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interaction between Burkholderia pseudomallei and Acanthamoeba Species Results in Coiling Phagocytosis, Endamebic Bacterial Survival, and Escape Timothy J. J. Inglis, Paul Rigby, Terry A. Robertson, Nichole S. Dutton, Mandy Henderson, and Barbara J. Chang Infect. Immun. March 2000 68: 1681-1686; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Conservation and Heterogeneity of vlsE among Human and Tick Isolates of Borrelia burgdorferi Radha Iyer, John M. Hardham, Gary P. Wormser, Ira Schwartz, and Steven J. Norris Infect. Immun. March 2000 68: 1714-1718; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Host Response and Inflammation:

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Reduced Th1, but Not Th2, Cytokine Production by Lymphocytes after In Vivo Exposure of Healthy Subjects to Endotoxin Fanny N. Lauw, Tessa ten Hove, Pascale E. P. Dekkers, Evert de Jonge, Sander J. H. van Deventer, and Tom van der Poll Infect. Immun. March 2000 68: 1014-1018; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning of Porcine NRAMP1 and Its Induction by Lipopolysaccharide, Tumor Necrosis Factor Alpha, and Interleukin-1: Role of CD14 and Mitogen-Activated Protein Kinases Guolong Zhang, Hua Wu, Christopher R. Ross, J. Ernest Minton, and Frank Blecha Infect. Immun. March 2000 68: 1086-1093; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Modulation of Cytokine Profiles by the Mycoplasma Superantigen Mycoplasma arthritidis Mitogen Parallels Susceptibility to Arthritis Induced by M. arthritidis Hong-Hua Mu, Allen D. Sawitzke, and Barry C. Cole Infect. Immun. March 2000 68: 1142-1149; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cytokines in Mycoplasma hyorhinis-Induced Arthritis in Pigs Bred Selectively for High and Low Immune Responses N. R. Jayagopala Reddy, Bruce N. Wilkie, Peter Borgs, and Bonnie A. Mallard Infect. Immun. March 2000 68: 1150-1155; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synergistic Epithelial Responses to Endotoxin and a Naturally Occurring Muramyl Peptide Tod A. Flak, Linda N. Heiss, Jacquelyn T. Engle, and William E. Goldman Infect. Immun. March 2000 68: 1235-1242; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Tumor Necrosis Factor Receptor p55-Deficient Mice Respond to Acute Yersinia enterocolitica Infection with Less Apoptosis and More Effective Host Resistance Yi-Xue Zhao, Ginette Lajoie, Hongwei Zhang, Basil Chiu, Ursula Payne, and Robert D. Inman Infect. Immun. March 2000 68: 1243-1251; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Febrile Core Temperature Is Essential for Optimal Host Defense in Bacterial Peritonitis Qinqqi Jiang, Alan S. Cross, Ishwar S. Singh, T. Timothy Chen, Rose M. Viscardi, and Jeffrey D. Hasday Infect. Immun. March 2000 68: 1265-1270; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interferon Consensus Sequence Binding Protein Confers Resistance against Yersinia enterocolitica Joachim Hein, Volkhard A. J. Kempf, Joachim Diebold, Nicole Bücheler, Sonja Preger, Ivan Horak, Andreas Sing, Uwe Kramer, and Ingo B. Autenrieth Infect. Immun. March 2000 68: 1408-1417; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Regulation of Immunoglobulin G2 Production by Prostaglandin E2 and Platelet-Activating Factor Yuichi Ishihara, Ji-Bo Zhang, Steve M. Quinn, Harvey A. Schenkein, Al M. Best, Suzanne E. Barbour, and John G. Tew Infect. Immun. March 2000 68: 1563-1568; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Immune Responses to Specific Antigens of Streptococcus pneumoniae and Moraxella catarrhalis in the Respiratory Tract Takao Samukawa, Noboru Yamanaka, Susan Hollingshead, Karin Klingman, and Howard Faden Infect. Immun. March 2000 68: 1569-1573; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bacterial Induction of Beta Interferon in Mice Is a Function of the Lipopolysaccharide Component Andreas Sing, Thomas Merlin, Hans-Peter Knopf, Peter J. Nielsen, Harald Loppnow, Chris Galanos, and Marina A. Freudenberg Infect. Immun. March 2000 68: 1600-1607; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Endotoxin-Induced Lung Inflammation Is Independent of the Complement Membrane Attack Complex R. B. Brauer, C. Gegenfurtner, B. Neumann, M. Stadler, C. D. Heidecke, and B. Holzmann Infect. Immun. March 2000 68: 1626-1632; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Influence of Synthetic Antiendotoxin Peptides on Lipopolysaccharide (LPS) Recognition and LPS-Induced Proinflammatory Cytokine Responses by Cells Expressing Membrane-Bound CD14 Akitaka Iwagaki, Massimo Porro, and Matthew Pollack Infect. Immun. March 2000 68: 1655-1663; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Enhanced Susceptibility to Subcutaneous Abscess Formation and Persistent Infection around Catheters Is Associated with Sustained Interleukin-1 Levels J. J. Boelens, S. A. J. Zaat, J. L. Murk, J. J. Weening, T. van der Poll, and J. Dankert Infect. Immun. March 2000 68: 1692-1695; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Lipopolysaccharide Entry in the Damaged Cornea and Specific Uptake by Polymorphonuclear Neutrophils C. L. Schultz, A. G. Buret, M. E. Olson, H. Ceri, R. R. Read, and D. W. Morck Infect. Immun. March 2000 68: 1731-1734; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bordetella pertussis Virulence Factors Affect Phagocytosis by Human Neutrophils Christine L. Weingart and Alison A. Weiss Infect. Immun. March 2000 68: 1735-1739; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Fungal and Parasitic Infections:

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B Cells Are Essential for Vaccination-Induced Resistance to Virulent Toxoplasma gondii Peter C. Sayles, George W. Gibson, and Lawrence L. Johnson Infect. Immun. March 2000 68: 1026-1033; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Decreased Production of Local Immunoglobulin A to Pneumocystis carinii in Bronchoalveolar Lavage Fluid from Human Immunodeficiency Virus-Positive Patients A. Jalil, P. Moja, C. Lambert, M. Perol, L. Cotte, J. M. Livrozet, A. Boibieux, J. M. Vergnon, F. Lucht, R. Tran, C. Contini, and C. Genin Infect. Immun. March 2000 68: 1054-1060; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of the Proinflammatory Response of Endothelial Cells to Candida albicans Infection Alison S. Orozco, Xiang Zhou, and Scott G. Filler Infect. Immun. March 2000 68: 1134-1141; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Malaria Infection Induces Rapid Elevation of the Soluble Fas Ligand Level in Serum and Subsequent T Lymphocytopenia: Possible Factors Responsible for the Differences in Susceptibility of Two Species of Macaca Monkeys to Plasmodium coatneyi Infection Jun Matsumoto, Satoru Kawai, Keiji Terao, Masashi Kirinoki, Yasuhiro Yasutomi, Masamichi Aikawa, and Hajime Matsuda Infect. Immun. March 2000 68: 1183-1188; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Metalloprotease Activity in a Small Heat Shock Protein of the Human Malaria Parasite Plasmodium vivax J. Mohamed Fakruddin, Sukla Biswas, and Yagya D. Sharma Infect. Immun. March 2000 68: 1202-1206; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

High Immunoglobulin G2 (IgG2) and Low IgG4 Levels Are Associated with Human Resistance to Plasmodium falciparum Malaria Christophe Aucan, Yves Traoré, François Tall, Boubacar Nacro, Thérèse Traoré-Leroux, Francis Fumoux, and Pascal Rihet Infect. Immun. March 2000 68: 1252-1258; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Eimeria tenella Infection Induces Local Gamma Interferon Production and Intestinal Lymphocyte Subpopulation Changes Cheol H. Yun, Hyun S. Lillehoj, and Kang D. Choi Infect. Immun. March 2000 68: 1282-1288; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The CD40/CD40 Ligand Interaction Is Required for Resistance to Toxoplasmic Encephalitis Gaby Reichmann, William Walker, Eric N. Villegas, Linden Craig, Guifang Cai, James Alexander, and Christopher A. Hunter Infect. Immun. March 2000 68: 1312-1318; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Subunit Vaccination of Mice against New World Cutaneous Leishmaniasis: Comparison of Three Proteins Expressed in Amastigotes and Six Adjuvants Toni Aebischer, Markus Wolfram, Silke I. Patzer, Thomas Ilg, Martin Wiese, and Peter Overath Infect. Immun. March 2000 68: 1328-1336; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of Novel Serine/Threonine Protein Phosphatases in Trypanosoma cruzi: a Potential Role in Control of Cytokinesis and Morphology George A. Orr, Craig Werner, Jun Xu, Marcia Bennett, Louis M. Weiss, Peter Takvorkan, Herbert B. Tanowitz, and Murray Wittner Infect. Immun. March 2000 68: 1350-1358; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Assessing the Binding of Four Plasmodium falciparum T Helper Cell Epitopes to HLA-DQ and Induction of T-Cell Responses in HLA-DQ Transgenic Mice Nattiya Pimtanothai, Marcela Parra, Armead H. Johnson, Chella S. David, and Carolyn Katovich Hurley Infect. Immun. March 2000 68: 1366-1373; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activated T Cells Induce Macrophages To Produce NO and Control Leishmania major in the Absence of Tumor Necrosis Factor Receptor p55 Michelle Nashleanas and Phillip Scott Infect. Immun. March 2000 68: 1428-1434; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cellular Changes and Apoptosis in the Spleens and Peripheral Blood of Mice Infected with Blood-Stage Plasmodium chabaudi chabaudi AS Helena Helmby, Gun Jönsson, and Marita Troye-Blomberg Infect. Immun. March 2000 68: 1485-1490; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Protection against Candidiasis by an Immunoglobulin G3 (IgG3) Monoclonal Antibody Specific for the Same Mannotriose as an IgM Protective Antibody Yongmoon Han, Marcia H. Riesselman, and Jim E. Cutler Infect. Immun. March 2000 68: 1649-1654; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Intestinal Epithelial Cell Apoptosis following Cryptosporidium parvum Infection Declan F. McCole, Lars Eckmann, Fabrice Laurent, and Martin F. Kagnoff Infect. Immun. March 2000 68: 1710-1713; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of Iron on Extracellular and Intracellular Growth of Penicillium marneffei D. Taramelli, S. Brambilla, G. Sala, A. Bruccoleri, C. Tognazioli, L. Riviera-Uzielli, and J. R. Boelaert Infect. Immun. March 2000 68: 1724-1726; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Microbial Immunity and Vaccines:

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Shigella flexneri 2a Strain CVD 1207, with Specific Deletions in virG, sen, set, and guaBA, Is Highly Attenuated in Humans Karen L. Kotloff, Fernando R. Noriega, Taraz Samandari, Marcelo B. Sztein, Genevieve A. Losonsky, James P. Nataro, William D. Picking, Eileen M. Barry, and Myron M. Levine Infect. Immun. March 2000 68: 1034-1039; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning of the Gene Encoding a 22-Kilodalton Cell Surface Antigen of Mycobacterium bovis BCG and Analysis of Its Potential for DNA Vaccination against Tuberculosis Philippe Lefèvre, Olivier Denis, Lucas De Wit, Audrey Tanghe, Paul Vandenbussche, Jean Content, and Kris Huygen Infect. Immun. March 2000 68: 1040-1047; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Salmonella enterica Serovar Typhimurium surA Mutants Are Attenuated and Effective Live Oral Vaccines Mark Sydenham, Gillian Douce, Frances Bowe, Saddif Ahmed, Steve Chatfield, and Gordon Dougan Infect. Immun. March 2000 68: 1109-1115; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Analyses of Constitutive and In Vivo-Induced Promoters in Attenuated Vaccine and Vector Strains of Vibrio cholerae Manohar John, Thomas I. Crean, Stephen B. Calderwood, and Edward T. Ryan Infect. Immun. March 2000 68: 1171-1175; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phase 2 Clinical Trial of Attenuated Salmonella enterica Serovar Typhi Oral Live Vector Vaccine CVD 908-htrA in U.S. Volunteers Carol O. Tacket, Marcelo B. Sztein, Steven S. Wasserman, Genevieve Losonsky, Karen L. Kotloff, Timothy L. Wyant, James P. Nataro, Robert Edelman, Judith Perry, Philip Bedford, David Brown, Stephen Chatfield, Gordon Dougan, and Myron M. Levine Infect. Immun. March 2000 68: 1196-1201; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Transient Loss of Resistance to Pulmonary Tuberculosis in p47phox/ Mice Andrea M. Cooper, Brahm H. Segal, Anthony A. Frank, Steven M. Holland, and Ian M. Orme Infect. Immun. March 2000 68: 1231-1234; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Regulatory Role for Interleukin 4 in Differential Inflammatory Responses in the Lung following Infection of Mice Primed with Th1- or Th2-Inducing Pertussis Vaccines Peter McGuirk and Kingston H. G. Mills Infect. Immun. March 2000 68: 1383-1390; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Vaccine Efficacy of Recombinant Plasmodium falciparum Merozoite Surface Protein 1 in Malaria-Naive, -Exposed, and/or -Rechallenged Aotus vociferans Monkeys Andrea F. Egan, Michael J. Blackman, and David C. Kaslow Infect. Immun. March 2000 68: 1418-1427; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Immunogenicity and Tolerance of a 7-Valent Pneumococcal Conjugate Vaccine in Nonresponders to the 23-Valent Pneumococcal Vaccine S. Zielen, I. Bühring, N. Strnad, J. Reichenbach, and D. Hofmann Infect. Immun. March 2000 68: 1435-1440; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

CpG Oligodeoxynucleotides Act as Adjuvants for Pneumococcal Polysaccharide-Protein Conjugate Vaccines and Enhance Antipolysaccharide Immunoglobulin G2a (IgG2a) and IgG3 Antibodies Rose S. Chu, Tera McCool, Neil S. Greenspan, John R. Schreiber, and Clifford V. Harding Infect. Immun. March 2000 68: 1450-1456; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Influence of the Bcg Locus on Natural Resistance to Primary Infection with the Facultative Intracellular Bacterium Francisella tularensis in Mice Lenka Hernychová and Marián Hajdúch Infect. Immun. March 2000 68: 1480-1484; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Listeria monocytogenes as a Short-Lived Delivery System for the Induction of Type 1 Cell-Mediated Immunity against the p36/LACK Antigen of Leishmania major Neirouz Soussi, Geneviève Milon, Jean-Hervé Colle, Evelyne Mougneau, Nicolas Glaichenhaus, and Pierre L. Goossens Infect. Immun. March 2000 68: 1498-1506; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Differential Regulation of CD4 Lymphocyte Recruitment between the Upper and Lower Regions of the Genital Tract during Chlamydia trachomatis Infection Kathleen A. Kelly, Jennifer C. Walker, Shimul H. Jameel, Heather L. Gray, and Roger G. Rank Infect. Immun. March 2000 68: 1519-1528; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phase 1 and Phase 2 Studies of Salmonella enterica Serovar Paratyphi A O-Specific Polysaccharide-Tetanus Toxoid Conjugates in Adults, Teenagers, and 2- to 4-Year-Old Children in Vietnam Edward Y. Konadu, Feng-Ying C. Lin, Vô Anh Hó, Nguyen Thi Thanh Thuy, Phan Van Bay, Tran Cong Thanh, Ha Ba Khiem, Dang Duc Trach, Arthur B. Karpas, Jianping Li, Dolores A. Bryla, John B. Robbins, and Shousun C. Szu Infect. Immun. March 2000 68: 1529-1534; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Construction and Characterization of a Salmonella enterica Serovar Typhimurium Clone Expressing a Salivary Adhesin of Streptococcus mutans under Control of the Anaerobically Inducible nirB Promoter Yan Huang, George Hajishengallis, and Suzanne M. Michalek Infect. Immun. March 2000 68: 1549-1556; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effective Preexposure Tuberculosis Vaccines Fail To Protect When They Are Given in an Immunotherapeutic Mode Joanne Turner, Elizabeth R. Rhoades, Marc Keen, John T. Belisle, Anthony A. Frank, and Ian M. Orme Infect. Immun. March 2000 68: 1706-1709; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

T-Cell Epitopes in Variable Segments of Chlamydia trachomatis Major Outer Membrane Protein Elicit Serovar-Specific Immune Responses in Infected Humans Linette Ortiz, Mark Angevine, Seon-Kyeong Kim, David Watkins, and Robert DeMars Infect. Immun. March 2000 68: 1719-1723; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Polymorphonuclear Neutrophils Are Necessary for the Recruitment of CD8+ T Cells in the Liver in a Pregnant Mouse Model of Chlamydophila abortus (Chlamydia psittaci Serotype 1) Infection Roberto Montes de Oca, Antonio J. Buendía, Laura Del Río, Joaquín Sánchez, Jesús Salinas, and Jose A. Navarro Infect. Immun. March 2000 68: 1746-1751; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Molecular and Cellular Pathogenesis:

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Construction and Characterization of an agr Deletion Mutant of Staphylococcus epidermidis Cuong Vuong, Friedrich Götz, and Michael Otto Infect. Immun. March 2000 68: 1048-1053; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Shift from Oral to Blood pH Is a Stimulus for Adaptive Gene Expression of Streptococcus gordonii CH1 and Induces Protection against Oxidative Stress and Enhanced Bacterial Growth by Expression of msrA Aldwin J. M. Vriesema, Jacob Dankert, and Sebastian A. J. Zaat Infect. Immun. March 2000 68: 1061-1068; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Legionella pneumophila iraAB Locus Is Required for Iron Assimilation, Intracellular Infection, and Virulence V. K. Viswanathan, Paul H. Edelstein, C. Dumais Pope, and Nicholas P. Cianciotto Infect. Immun. March 2000 68: 1069-1079; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

New Method To Generate Enzymatically Deficient Clostridium difficile Toxin B as an Antigen for Immunization Harald Genth, Jörg Selzer, Christian Busch, Jürgen Dumbach, Fred Hofmann, Klaus Aktories, and Ingo Just Infect. Immun. March 2000 68: 1094-1101; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cytotoxic Activity of Coagulase-Negative Staphylococci in Bovine Mastitis Songlin Zhang and Carol W. Maddox Infect. Immun. March 2000 68: 1102-1108; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Distribution of Core Oligosaccharide Types in Lipopolysaccharides from Escherichia coli Karen Amor, David E. Heinrichs, Emilisa Frirdich, Kim Ziebell, Roger P. Johnson, and Chris Whitfield Infect. Immun. March 2000 68: 1116-1124; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Intracellular Infection by the Human Granulocytic Ehrlichiosis Agent Inhibits Human Neutrophil Apoptosis Kiyotaka Yoshiie, Hyung-Yong Kim, Jason Mott, and Yasuko Rikihisa Infect. Immun. March 2000 68: 1125-1133; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synthetic Peptide Immunogens Elicit Polyclonal and Monoclonal Antibodies Specific for Linear Epitopes in the D Motifs of Staphylococcus aureus Fibronectin-Binding Protein, Which Are Composed of Amino Acids That Are Essential for Fibronectin Binding Mario Huesca, Qing Sun, Robert Peralta, Gulnar M. Shivji, Daniel N. Sauder, and Martin J. McGavin Infect. Immun. March 2000 68: 1156-1163; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Actinobacillus pleuropneumoniae Iron Transport: a Set of exbBD Genes Is Transcriptionally Linked to the tbpB Gene and Required for Utilization of Transferrin-Bound Iron Walaiporn Tonpitak, Svenja Thiede, Winfried Oswald, Nina Baltes, and Gerald-F. Gerlach Infect. Immun. March 2000 68: 1164-1170; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Emerging Family of Proline-Specific Peptidases of Porphyromonas gingivalis: Purification and Characterization of Serine Dipeptidyl Peptidase, a Structural and Functional Homologue of Mammalian Prolyl Dipeptidyl Peptidase IV Agnieszka Banbula, Marcin Bugno, Jason Goldstein, Jane Yen, Daniel Nelson, James Travis, and Jan Potempa Infect. Immun. March 2000 68: 1176-1182; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Tumor Necrosis Factor Alpha and Interleukin 1 Up-Regulate Gastric Mucosal Fas Antigen Expression in Helicobacter pylori Infection JeanMarie Houghton, Lisa S. Macera-Bloch, Lawrence Harrison, Kyung H. Kim, and Reju M. Korah Infect. Immun. March 2000 68: 1189-1195; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pathogenic Mechanism of Mouse Brain Damage Caused by Oral Infection with Shiga Toxin-Producing Escherichia coli O157:H7 Eiji Kita, Yoshihisa Yunou, Takaaki Kurioka, Hiroko Harada, Shinji Yoshikawa, Keiichi Mikasa, and Nobutaka Higashi Infect. Immun. March 2000 68: 1207-1214; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Group A Streptococcal Virulence Factors in Adherence to Keratinocytes Gary L. Darmstadt, Laurel Mentele, Andreas Podbielski, and Craig E. Rubens Infect. Immun. March 2000 68: 1215-1221; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phospholipid Synthesis by Staphylococcus aureus during (Sub)Lethal Attack by Mammalian 14-Kilodalton Group IIA Phospholipase A2 Amy K. Foreman-Wykert, Jerrold Weiss, and Peter Elsbach Infect. Immun. March 2000 68: 1259-1264; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Iron Acquisition from Pseudomonas aeruginosa Siderophores by Human Phagocytes: an Additional Mechanism of Host Defense through Iron Sequestration? Bradley E. Britigan, George T. Rasmussen, Oyebode Olakanmi, and Charles D. Cox Infect. Immun. March 2000 68: 1271-1275; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutations in the S1 Subunit of Pertussis Toxin That Affect Secretion Kathleen A. Craig-Mylius, Trevor H. Stenson, and Alison A. Weiss Infect. Immun. March 2000 68: 1276-1281; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Induction of Necrosis in Human Neutrophils by Shigella flexneri Requires Type III Secretion, IpaB and IpaC Invasins, and Actin Polymerization Mathias François, Véronique Le Cabec, Marie-Ange Dupont, Philippe J. Sansonetti, and Isabelle Maridonneau-Parini Infect. Immun. March 2000 68: 1289-1296; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutation and Recombination in the Upstream Homology Box-Flanked ospE-Related Genes of the Lyme Disease Spirochetes Result in the Development of New Antigenic Variants during Infection Shian Ying Sung, John V. McDowell, Jason A. Carlyon, and Richard T. Marconi Infect. Immun. March 2000 68: 1319-1327; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of In Vitro DNA Binding Sites of the EUO Protein of Chlamydia psittaci Li Zhang, Martha M. Howe, and Thomas P. Hatch Infect. Immun. March 2000 68: 1337-1349; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Decay-Accelerating Factor Domains and Anchorage in Internalization of Dr-Fimbriated Escherichia coli R. Selvarangan, P. Goluszko, V. Popov, J. Singhal, T. Pham, D. M. Lublin, S. Nowicki, and B. Nowicki Infect. Immun. March 2000 68: 1391-1399; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Iha: a Novel Escherichia coli O157:H7 Adherence-Conferring Molecule Encoded on a Recently Acquired Chromosomal Island of Conserved Structure Phillip I. Tarr, Sima S. Bilge, James C. Vary, Jr., Srdjan Jelacic, Rebecca L. Habeeb, Teresa R. Ward, Michael R. Baylor, and Thomas E. Besser Infect. Immun. March 2000 68: 1400-1407; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of Porphyromonas gingivalis-Induced Degradation of Epithelial Cell Junctional Complexes Jannet Katz, Vijaya Sambandam, John H. Wu, Suzanne M. Michalek, and Daniel F. Balkovetz Infect. Immun. March 2000 68: 1441-1449; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Chlamydial Development Is Adversely Affected by Minor Changes in Amino Acid Supply, Blood Plasma Amino Acid Levels, and Glucose Deprivation Angela Harper, Christopher I. Pogson, Meirion L. Jones, and John H. Pearce Infect. Immun. March 2000 68: 1457-1464; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Use of Defined Mutants To Assess the Role of the Campylobacter rectus S-Layer in Bacterium-Epithelial Cell Interactions Beinan Wang, Ellen Kraig, and David Kolodrubetz Infect. Immun. March 2000 68: 1465-1473; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of Two Distinct Types of Flagellar Cap Proteins, FliD, in Pseudomonas aeruginosa Shiwani K. Arora, Nandini Dasgupta, Stephen Lory, and Reuben Ramphal Infect. Immun. March 2000 68: 1474-1479; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Virulence Regulatory Protein ToxR Mediates Enhanced Bile Resistance in Vibrio cholerae and Other Pathogenic Vibrio Species Daniele Provenzano, Darren A. Schuhmacher, Justin L. Barker, and Karl E. Klose Infect. Immun. March 2000 68: 1491-1497; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Colonization of the Respiratory Tract by a Virulent Strain of Avian Escherichia coli Requires Carriage of a Conjugative Plasmid C. A. Ginns, M. L. Benham, L. M. Adams, K. G. Whithear, K. A. Bettelheim, B. S. Crabb, and G. F. Browning Infect. Immun. March 2000 68: 1535-1541; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Relative Roles of Pneumolysin and Hydrogen Peroxide from Streptococcus pneumoniae in Inhibition of Ependymal Ciliary Beat Frequency Robert A. Hirst, Kulvinder S. Sikand, Andrew Rutman, Timothy J. Mitchell, Peter W. Andrew, and Christopher O'Callaghan Infect. Immun. March 2000 68: 1557-1562; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Serum Resistance in Haemophilus ducreyi Requires Outer Membrane Protein DsrA Christopher Elkins, K. John Morrow, Jr., and Bonnie Olsen Infect. Immun. March 2000 68: 1608-1619; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bacterial Phosphorylcholine Decreases Susceptibility to the Antimicrobial Peptide LL-37/hCAP18 Expressed in the Upper Respiratory Tract Elena S. Lysenko, Jane Gould, Robert Bals, James M. Wilson, and Jeffrey N. Weiser Infect. Immun. March 2000 68: 1664-1671; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Complement Activation in Mycoplasma fermentans-Induced Mycoplasma Clearance from Infected Cells: Probing of the Organism with Monoclonal Antibodies against M161Ag Satomi Kikkawa, Misako Matsumoto, Tsuguo Sasaki, Miyuki Nishiguchi, Kazuhiko Tanaka, Kumao Toyoshima, and Tsukasa Seya Infect. Immun. March 2000 68: 1672-1680; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Roles of the Surface Layer Proteins of Campylobacter fetus subsp. fetus in Ovine Abortion R. Grogono-Thomas, J. Dworkin, M. J. Blaser, and D. G. Newell Infect. Immun. March 2000 68: 1687-1691; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Macropinocytosis as a Mechanism of Entry into Primary Human Urethral Epithelial Cells by Neisseria gonorrhoeae Michael K. Zenni, Peter C. Giardina, Hillery A. Harvey, Jianqiang Shao, Margaret R. Ketterer, David M. Lubaroff, Richard D. Williams, and Michael A. Apicella Infect. Immun. March 2000 68: 1696-1699; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cytotoxic Cell Vacuolating Activity from Vibrio cholerae Hemolysin Ana Coelho, João R. C. Andrade, Ana Carolina P. Vicente, and Victor J. Dirita Infect. Immun. March 2000 68: 1700-1705; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Stability of Borrelia burgdorferi bdr Loci In Vitro and In Vivo Wolfram R. Zückert and Alan G. Barbour Infect. Immun. March 2000 68: 1727-1730; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Lipopolysaccharides of Brucella abortus and Brucella melitensis Induce Nitric Oxide Synthesis in Rat Peritoneal Macrophages Luis López-Urrutia, Andrés Alonso, Maria Luisa Nieto, Yolanda Bayón, Antonio Orduña, and Mariano Sánchez Crespo Infect. Immun. March 2000 68: 1740-1745; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Molecular Genomics:

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Direct Quantitative Transcript Analysis of the agr Regulon of Staphylococcus aureus during Human Infection in Comparison to the Expression Profile In Vitro Christiane Goerke, Silvia Campana, Manfred G. Bayer, Gerd Döring, Konrad Botzenhart, and Christiane Wolz Infect. Immun. March 2000 68: 1304-1311; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Relationships between Clinical Isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: Characterization of "Atypical" Pneumococci and Organisms Allied to S. mitis Harboring S. pneumoniae Virulence Factor-Encoding Genes Adrian M. Whatmore, Androulla Efstratiou, A. Paul Pickerill, Karen Broughton, Geoffrey Woodard, Daniel Sturgeon, Robert George, and Christopher G. Dowson Infect. Immun. March 2000 68: 1374-1382; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Infectious CTX and the Vibrio Pathogenicity Island Prophage in Vibrio mimicus: Evidence for Recent Horizontal Transfer between V. mimicus and V. cholerae E. Fidelma Boyd, Kathryn E. Moyer, Lei Shi, and Matthew K. Waldor Infect. Immun. March 2000 68: 1507-1513; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular and Evolutionary Characterization of the cp32/18 Family of Supercoiled Plasmids in Borrelia burgdorferi 297 Melissa J. Caimano, Xiaofeng Yang, Taissia G. Popova, Michael L. Clawson, Darrin R. Akins, Michael V. Norgard, and Justin D. Radolf Infect. Immun. March 2000 68: 1574-1586; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Genome Analysis of the Pathogenic Spirochetes Borrelia burgdorferi and Treponema pallidum G. Subramanian, Eugene V. Koonin, and L. Aravind Infect. Immun. March 2000 68: 1633-1648; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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