Cover photograph (Copyright © 2005, American Society for Microbiology. All Rights Reserved.): Expression of enteropathogenic Escherichia coli type III effector protein EspG in Saccharomyces cerevisiae cells disrupts the microtubule structure. S. cerevisiae cells expressing either glutathione S-transferase (GST) (top row) or GST-EspG (bottom four rows) were stained with antibodies raised against GST (red) and α-tubulin (green) and with 4',6-diamidino-2-phenylindone (blue). (See related article on page 2586.)