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Molecular Pathogenesis:

Maria Kostakioti and Christos Stathopoulos

Role of the -Helical Linker of the C-Terminal Translocator in the Biogenesis of the Serine Protease Subfamily of Autotransporters
Infect. Immun. 2006 74: 4961-4969. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sreedhar R. Nallapareddy and Barbara E. Murray

Ligand-Signaled Upregulation of Enterococcus faecalis ace Transcription, a Mechanism for Modulating Host-E. faecalis Interaction
Infect. Immun. 2006 74: 4982-4989. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Linsen Cao, Alla Volgina, Jonathan Korostoff, and Joseph M. DiRienzo

Role of Intrachain Disulfides in the Activities of the CdtA and CdtC Subunits of the Cytolethal Distending Toxin of Actinobacillus actinomycetemcomitans
Infect. Immun. 2006 74: 4990-5002. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Berit Schulte, Dirk Linke, Sandra Klumpp, Martin Schaller, Tanja Riess, Ingo B. Autenrieth, and Volkhard A. J. Kempf

Bartonella quintana Variably Expressed Outer Membrane Proteins Mediate Vascular Endothelial Growth Factor Secretion but Not Host Cell Adherence
Infect. Immun. 2006 74: 5003-5013. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yumi Kumagai, Zhihui Cheng, Mingqun Lin, and Yasuko Rikihisa

Biochemical Activities of Three Pairs of Ehrlichia chaffeensis Two-Component Regulatory System Proteins Involved in Inhibition of Lysosomal Fusion
Infect. Immun. 2006 74: 5014-5022. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Nadine Lemaître, Florent Sebbane, Daniel Long, and B. Joseph Hinnebusch

Yersinia pestis YopJ Suppresses Tumor Necrosis Factor Alpha Induction and Contributes to Apoptosis of Immune Cells in the Lymph Node but Is Not Required for Virulence in a Rat Model of Bubonic Plague
Infect. Immun. 2006 74: 5126-5131. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tracey S. Hanks, Mengyao Liu, Michael J. McClure, Maki Fukumura, Angela Duffy, and Benfang Lei

Differential Regulation of Iron- and Manganese-Specific MtsABC and Heme-Specific HtsABC Transporters by the Metalloregulator MtsR of Group A Streptococcus
Infect. Immun. 2006 74: 5132-5139. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eva Bjur, Sofia Eriksson-Ygberg, Fredrik Åslund, and Mikael Rhen

Thioredoxin 1 Promotes Intracellular Replication and Virulence of Salmonella enterica Serovar Typhimurium
Infect. Immun. 2006 74: 5140-5151. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sruti DebRoy, Virginia Aragon, Sherry Kurtz, and Nicholas P. Cianciotto

Legionella pneumophila Mip, a Surface-Exposed Peptidylproline cis-trans-Isomerase, Promotes the Presence of Phospholipase C-Like Activity in Culture Supernatants
Infect. Immun. 2006 74: 5152-5160. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jason B. Harris, Andrea Baresch-Bernal, Sean M. Rollins, Ashfaqul Alam, Regina C. LaRocque, Margaret Bikowski, Amanda F. Peppercorn, Martin Handfield, Jeffery D. Hillman, Firdausi Qadri, Stephen B. Calderwood, Elizabeth Hohmann, Robert F. Breiman, W. Abdullah Brooks, and Edward T. Ryan

Identification of In Vivo-Induced Bacterial Protein Antigens during Human Infection with Salmonella enterica Serovar Typhi
Infect. Immun. 2006 74: 5161-5168. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Timothy F. Murphy, Charmaine Kirkham, and Alan J. Lesse

Construction of a Mutant and Characterization of the Role of the Vaccine Antigen P6 in Outer Membrane Integrity of Nontypeable Haemophilus influenzae
Infect. Immun. 2006 74: 5169-5176. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Qilong Xu, Sunita V. Seemanapalli, Kristy McShan, and Fang Ting Liang

Constitutive Expression of Outer Surface Protein C Diminishes the Ability of Borrelia burgdorferi To Evade Specific Humoral Immunity
Infect. Immun. 2006 74: 5177-5184. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. Behling-Kelly, H. Vonderheid, Kwang Sik Kim, L. B. Corbeil, and C. J. Czuprynski

Roles of Cellular Activation and Sulfated Glycans in Haemophilus somnus Adherence to Bovine Brain Microvascular Endothelial Cells
Infect. Immun. 2006 74: 5311-5318. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alison R. Kerr, Gavin K. Paterson, Jackie McCluskey, Francesco Iannelli, Marco R. Oggioni, Gianni Pozzi, and Tim J. Mitchell

The Contribution of PspC to Pneumococcal Virulence Varies between Strains and Is Accomplished by Both Complement Evasion and Complement-Independent Mechanisms
Infect. Immun. 2006 74: 5319-5324. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alka Mehra, Jesse Fredrick, William A. Petri, Jr., Sudha Bhattacharya, and Alok Bhattacharya

Expression and Function of a Family of Transmembrane Kinases from the Protozoan Parasite Entamoeba histolytica
Infect. Immun. 2006 74: 5341-5351. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Jennifer M. Slaney, Alexandra Gallagher, Joseph Aduse-Opoku, Keith Pell, and Michael A. Curtis

Mechanisms of Resistance of Porphyromonas gingivalis to Killing by Serum Complement
Infect. Immun. 2006 74: 5352-5361. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shaoguang Wu, Jai Shin, Guangming Zhang, Mitchell Cohen, Augusto Franco, and Cynthia L. Sears

The Bacteroides fragilis Toxin Binds to a Specific Intestinal Epithelial Cell Receptor
Infect. Immun. 2006 74: 5382-5390. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Connie K. P. Tam, Christina Morris, and Jim Hackett

The Salmonella enterica Serovar Typhi Type IVB Self-Association Pili Are Detached from the Bacterial Cell by the PilV Minor Pilus Proteins
Infect. Immun. 2006 74: 5414-5418. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fungal and Parasitic Infections:

Joshua J. Reece, Mark C. Siracusa, and Alan L. Scott

Innate Immune Responses to Lung-Stage Helminth Infection Induce Alternatively Activated Alveolar Macrophages
Infect. Immun. 2006 74: 4970-4981. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

James I. Ito, Joseph M. Lyons, Teresa B. Hong, Daniel Tamae, Yi-Kuang Liu, Sharon P. Wilczynski, and Markus Kalkum

Vaccinations with Recombinant Variants of Aspergillus fumigatus Allergen Asp f 3 Protect Mice against Invasive Aspergillosis
Infect. Immun. 2006 74: 5075-5084. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Sabine Specht, Michael Saeftel, Manuela Arndt, Elmar Endl, Bettina Dubben, Nancy A. Lee, James J. Lee, and Achim Hoerauf

Lack of Eosinophil Peroxidase or Major Basic Protein Impairs Defense against Murine Filarial Infection
Infect. Immun. 2006 74: 5236-5243. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Donna M. MacCallum, Helen Findon, Claire C. Kenny, Geraldine Butler, Ken Haynes, and Frank C. Odds

Different Consequences of ACE2 and SWI5 Gene Disruptions for Virulence of Pathogenic and Nonpathogenic Yeasts
Infect. Immun. 2006 74: 5244-5248. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christopher C. Keller, Ouma Yamo, Collins Ouma, John Michael Ong'echa, David Ounah, James B. Hittner, John M. Vulule, and Douglas J. Perkins

Acquisition of Hemozoin by Monocytes Down-Regulates Interleukin-12 p40 (IL-12p40) Transcripts and Circulating IL-12p70 through an IL-10-Dependent Mechanism: In Vivo and In Vitro Findings in Severe Malarial Anemia
Infect. Immun. 2006 74: 5249-5260. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Asna A. Siddiqui, Robin J. Shattock, and Thomas S. Harrison

Role of Capsule and Interleukin-6 in Long-Term Immune Control of Cryptococcus neoformans Infection by Specifically Activated Human Peripheral Blood Mononuclear Cells
Infect. Immun. 2006 74: 5302-5310. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions:

Satoru Inagaki, Shinsuke Onishi, Howard K. Kuramitsu, and Ashu Sharma

Porphyromonas gingivalis Vesicles Enhance Attachment, and the Leucine-Rich Repeat BspA Protein Is Required for Invasion of Epithelial Cells by "Tannerella forsythia"
Infect. Immun. 2006 74: 5023-5028. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wilson J. Ribot, Rekha G. Panchal, Katherine C. Brittingham, Gordon Ruthel, Tara A. Kenny, Douglas Lane, Bob Curry, Timothy A. Hoover, Arthur M. Friedlander, and Sina Bavari

Anthrax Lethal Toxin Impairs Innate Immune Functions of Alveolar Macrophages and Facilitates Bacillus anthracis Survival
Infect. Immun. 2006 74: 5029-5034. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yongqun He, Sherry Reichow, Sheela Ramamoorthy, Xicheng Ding, Raju Lathigra, Johanna C. Craig, Bruno W. S. Sobral, Gerhardt G. Schurig, Nammalwar Sriranganathan, and Stephen M. Boyle

Brucella melitensis Triggers Time-Dependent Modulation of Apoptosis and Down-Regulation of Mitochondrion-Associated Gene Expression in Mouse Macrophages
Infect. Immun. 2006 74: 5035-5046. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David J. Klumpp, Matthew T. Rycyk, Michael C. Chen, Praveen Thumbikat, Shomit Sengupta, and Anthony J. Schaeffer

Uropathogenic Escherichia coli Induces Extrinsic and Intrinsic Cascades To Initiate Urothelial Apoptosis
Infect. Immun. 2006 74: 5106-5113. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Amy M. McCord, Sandra I. Resto-Ruiz, and Burt E. Anderson

Autocrine Role for Interleukin-8 in Bartonella henselae-Induced Angiogenesis
Infect. Immun. 2006 74: 5185-5190. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Leanne Peiser, Katherine Makepeace, Annette Plüddemann, Silvana Savino, J. Claire Wright, Mariagrazia Pizza, Rino Rappuoli, E. Richard Moxon, and Siamon Gordon

Identification of Neisseria meningitidis Nonlipopolysaccharide Ligands for Class A Macrophage Scavenger Receptor by Using a Novel Assay
Infect. Immun. 2006 74: 5191-5199. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

K. A. Rzomp, A. R. Moorhead, and M. A. Scidmore

The GTPase Rab4 Interacts with Chlamydia trachomatis Inclusion Membrane Protein CT229
Infect. Immun. 2006 74: 5362-5373. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Justin A. Boddey, Cameron P. Flegg, Chris J. Day, Ifor R. Beacham, and Ian R. Peak

Temperature-Regulated Microcolony Formation by Burkholderia pseudomallei Requires pilA and Enhances Association with Cultured Human Cells
Infect. Immun. 2006 74: 5374-5381. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Romney M. Hyland, Paul Beck, George L. Mulvey, Pavel I. Kitov, and Glen D. Armstrong

N-Acetyllactosamine Conjugated to Gold Nanoparticles Inhibits Enteropathogenic Escherichia coli Colonization of the Epithelium in Human Intestinal Biopsy Specimens
Infect. Immun. 2006 74: 5419-5421. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bacterial Infections:

Bärbel Stecher, Günther Paesold, Manja Barthel, Marcus Kremer, Jonathan Jantsch, Thomas Stallmach, Mathias Heikenwalder, and Wolf-Dietrich Hardt

Chronic Salmonella enterica Serovar Typhimurium-Induced Colitis and Cholangitis in Streptomycin-Pretreated Nramp1^+/+ Mice
Infect. Immun. 2006 74: 5047-5057. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Olaf Hoffmann, Janine Zweigner, Shannon H. Smith, Dorette Freyer, Cordula Mahrhofer, Emilie Dagand, Elaine I. Tuomanen, and Joerg R. Weber

Interplay of Pneumococcal Hydrogen Peroxide and Host-Derived Nitric Oxide
Infect. Immun. 2006 74: 5058-5066. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ashwin Balagopal, Amanda Shearer MacFarlane, Nrusingh Mohapatra, Shilpa Soni, John S. Gunn, and Larry S. Schlesinger

Characterization of the Receptor-Ligand Pathways Important for Entry and Survival of Francisella tularensis in Human Macrophages
Infect. Immun. 2006 74: 5114-5125. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Derek J. Fisher, Mariano E. Fernandez-Miyakawa, Sameera Sayeed, Rachael Poon, Victoria Adams, Julian I. Rood, Francisco A. Uzal, and Bruce A. McClane

Dissecting the Contributions of Clostridium perfringens Type C Toxins to Lethality in the Mouse Intravenous Injection Model
Infect. Immun. 2006 74: 5200-5210. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christopher Chang and Jeff F. Miller

Campylobacter jejuni Colonization of Mice with Limited Enteric Flora
Infect. Immun. 2006 74: 5261-5271. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Siouxsie Wiles, Karen M. Pickard, Katian Peng, Thomas T. MacDonald, and Gad Frankel

In Vivo Bioluminescence Imaging of the Murine Pathogen Citrobacter rodentium
Infect. Immun. 2006 74: 5391-5396. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Randall J. Basaraba, Erin E. Smith, Crystal A. Shanley, and Ian M. Orme

Pulmonary Lymphatics Are Primary Sites of Mycobacterium tuberculosis Infection in Guinea Pigs Infected by Aerosol
Infect. Immun. 2006 74: 5397-5401. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Host Response and Inflammation:

Elena Rydkina, Abha Sahni, Raymond B. Baggs, David J. Silverman, and Sanjeev K. Sahni

Infection of Human Endothelial Cells with Spotted Fever Group Rickettsiae Stimulates Cyclooxygenase 2 Expression and Release of Vasoactive Prostaglandins
Infect. Immun. 2006 74: 5067-5074. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kazuhisa Ouhara, Hitoshi Komatsuzawa, Hideki Shiba, Yushi Uchida, Toshihisa Kawai, Koji Sayama, Koji Hashimoto, Martin A. Taubman, Hidemi Kurihara, and Motoyuki Sugai

Actinobacillus actinomycetemcomitans Outer Membrane Protein 100 Triggers Innate Immunity and Production of ß-Defensin and the 18-Kilodalton Cationic Antimicrobial Protein through the Fibronectin-Integrin Pathway in Human Gingival Epithelial Cells
Infect. Immun. 2006 74: 5211-5220. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pu Feng, Allan L. Truant, Joseph J. Meissler, Jr., John P. Gaughan, Martin W. Adler, and Toby K. Eisenstein

Morphine Withdrawal Lowers Host Defense to Enteric Bacteria: Spontaneous Sepsis and Increased Sensitivity to Oral Salmonella enterica Serovar Typhimurium Infection
Infect. Immun. 2006 74: 5221-5226. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hongyan Xiao, Javed Siddiqui, and Daniel G. Remick

Mechanisms of Mortality in Early and Late Sepsis
Infect. Immun. 2006 74: 5227-5235. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susanne F. de Haar, Pieter S. Hiemstra, Martijn T. J. M. van Steenbergen, Vincent Everts, and Wouter Beertsen

Role of Polymorphonuclear Leukocyte-Derived Serine Proteinases in Defense against Actinobacillus actinomycetemcomitans
Infect. Immun. 2006 74: 5284-5291. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kyoko Inagaki-Ohara, Fitriya Nurannisa Dewi, Hajime Hisaeda, Adrian L. Smith, Fumiko Jimi, Maki Miyahira, Ayman Samir Farid Abdel-Aleem, Yoichiro Horii, and Yukifumi Nawa

Intestinal Intraepithelial Lymphocytes Sustain the Epithelial Barrier Function against Eimeria vermiformis Infection
Infect. Immun. 2006 74: 5292-5301. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yan Sun, Amy G. Hise, Carolyn M. Kalsow, and Eric Pearlman

Staphylococcus aureus-Induced Corneal Inflammation Is Dependent on Toll-Like Receptor 2 and Myeloid Differentiation Factor 88
Infect. Immun. 2006 74: 5325-5332. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Caroline A. Rowland, Ganjana Lertmemongkolchai, Alison Bancroft, Ashraful Haque, M. Stephen Lever, Kate F. Griffin, Matthew C. Jackson, Michelle Nelson, Anne O'Garra, Richard Grencis, Gregory J. Bancroft, and Roman A. Lukaszewski

Critical Role of Type 1 Cytokines in Controlling Initial Infection with Burkholderia mallei
Infect. Immun. 2006 74: 5333-5340. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Matthew S. Lawlor, Scott A. Handley, and Virginia L. Miller

Comparison of the Host Responses to Wild-Type and cpsB Mutant Klebsiella pneumoniae Infections
Infect. Immun. 2006 74: 5402-5407. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Molecular Genomics:

Martin J. Callaghan, Keith A. Jolley, and Martin C. J. Maiden

Opacity-Associated Adhesin Repertoire in Hyperinvasive Neisseria meningitidis
Infect. Immun. 2006 74: 5085-5094. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Kai Shen, Sameera Sayeed, Patricia Antalis, John Gladitz, Azad Ahmed, Bethany Dice, Benjamin Janto, Richard Dopico, Randy Keefe, Jay Hayes, Sandra Johnson, Sujun Yu, Nathan Ehrlich, Jennifer Jocz, Laura Kropp, Ray Wong, Robert M. Wadowsky, Malcolm Slifkin, Robert A. Preston, Geza Erdos, J. Christopher Post, Garth D. Ehrlich, and Fen Z. Hu

Extensive Genomic Plasticity in Pseudomonas aeruginosa Revealed by Identification and Distribution Studies of Novel Genes among Clinical Isolates
Infect. Immun. 2006 74: 5272-5283. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carl Brinkley, Valerie Burland, Rogéria Keller, Debra J. Rose, Adam T. Boutin, Sara A. Klink, Frederick R. Blattner, and James B. Kaper

Nucleotide Sequence Analysis of the Enteropathogenic Escherichia coli Adherence Factor Plasmid pMAR7
Infect. Immun. 2006 74: 5408-5413. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Microbial Immunity and Vaccines:

Rebecca Tempel, Xin-He Lai, Lidia Crosa, Briana Kozlowicz, and Fred Heffron

Attenuated Francisella novicida Transposon Mutants Protect Mice against Wild-Type Challenge
Infect. Immun. 2006 74: 5095-5105. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Hyuk Chu, Jung-Hee Lee, Seung-Hoon Han, Se-Yoon Kim, Nam-Hyuk Cho, Ik-Sang Kim, and Myung-Sik Choi

Exploitation of the Endocytic Pathway by Orientia tsutsugamushi in Nonprofessional Phagocytes
Infect. Immun. 2006 74: 5422. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.