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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
Infect. Immun. 2007 75: 5073. [Full Text] [PDF]  

Guest Commentary:

Arturo Casadevall and Liise-anne Pirofski

Antibody-Mediated Protection through Cross-Reactivity Introduces a Fungal Heresy into Immunological Dogma
Infect. Immun. 2007 75: 5074-5078. [Full Text] [PDF]  

Minireviews:

Karla J. Fullner Satchell

MARTX, Multifunctional Autoprocessing Repeats-in-Toxin Toxins
Infect. Immun. 2007 75: 5079-5084. [Full Text] [PDF]  

Fungal and Parasitic Infections:

Anna Rachini, Donatella Pietrella, Patrizia Lupo, Antonella Torosantucci, Paola Chiani, Carla Bromuro, Carla Proietti, Francesco Bistoni, Antonio Cassone, and Anna Vecchiarelli

An Anti-ß-Glucan Monoclonal Antibody Inhibits Growth and Capsule Formation of Cryptococcus neoformans In Vitro and Exerts Therapeutic, Anticryptococcal Activity In Vivo
Infect. Immun. 2007 75: 5085-5094. [Abstract] [Full Text] [PDF]  

Manuela Verastegui, Robert H. Gilman, Yanina Arana, Dylan Barber, Jeanette Velásquez, Marilu Farfán, Nancy Chile, Jon C. Kosek, Margaret Kosek, Hector H. Garcia, Armando Gonzalez and the Cysticercosis Working Group in Peru

Taenia solium Oncosphere Adhesion to Intestinal Epithelial and Chinese Hamster Ovary Cells In Vitro
Infect. Immun. 2007 75: 5158-5166. [Abstract] [Full Text] [PDF]  

Florence Dzierszinski, Marion Pepper, Jason S. Stumhofer, David F. LaRosa, Emma H. Wilson, Laurence A. Turka, Sandra K. Halonen, Christopher A. Hunter, and David S. Roos

Presentation of Toxoplasma gondii Antigens via the Endogenous Major Histocompatibility Complex Class I Pathway in Nonprofessional and Professional Antigen-Presenting Cells
Infect. Immun. 2007 75: 5200-5209. [Abstract] [Full Text] [PDF]  

Ipsita Pal-Bhowmick, Monika Mehta, Isabelle Coppens, Shobhona Sharma, and Gotam K. Jarori

Protective Properties and Surface Localization of Plasmodium falciparum Enolase
Infect. Immun. 2007 75: 5500-5508. [Abstract] [Full Text] [PDF]  

Yamei Jin, Chahnaz Kebaier, and Jerome Vanderberg

Direct Microscopic Quantification of Dynamics of Plasmodium berghei Sporozoite Transmission from Mosquitoes to Mice
Infect. Immun. 2007 75: 5532-5539. [Abstract] [Full Text] [PDF]  

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions:

Beth A. McNichol, Susan B. Rasmussen, Humberto M. Carvalho, Karen C. Meysick, and Alison D. O'Brien

Two Domains of Cytotoxic Necrotizing Factor Type 1 Bind the Cellular Receptor, Laminin Receptor Precursor Protein
Infect. Immun. 2007 75: 5095-5104. [Abstract] [Full Text] [PDF]  

Ralf M. Leonhardt, Seung-Joon Lee, Paula B. Kavathas, and Peter Cresswell

Severe Tryptophan Starvation Blocks Onset of Conventional Persistence and Reduces Reactivation of Chlamydia trachomatis
Infect. Immun. 2007 75: 5105-5117. [Abstract] [Full Text] [PDF]  

Anja Lührmann and Craig R. Roy

Coxiella burnetii Inhibits Activation of Host Cell Apoptosis through a Mechanism That Involves Preventing Cytochrome c Release from Mitochondria
Infect. Immun. 2007 75: 5282-5289. [Abstract] [Full Text] [PDF]  

Hester J. Bootsma, Michael Egmont-Petersen, and Peter W. M. Hermans

Analysis of the In Vitro Transcriptional Response of Human Pharyngeal Epithelial Cells to Adherent Streptococcus pneumoniae: Evidence for a Distinct Response to Encapsulated Strains
Infect. Immun. 2007 75: 5489-5499. [Abstract] [Full Text] [PDF] [Supplemental material]  

Host Response and Inflammation:

Sicheng Wen, Dominique Velin, Christian P. Felley, Likun Du, Pierre Michetti, and Qiang Pan-Hammarström

Expression of Helicobacter pylori Virulence Factors and Associated Expression Profiles of Inflammatory Genes in the Human Gastric Mucosa
Infect. Immun. 2007 75: 5118-5126. [Abstract] [Full Text] [PDF]  

Sheetal Gandotra, Sihyug Jang, Peter J. Murray, Padmini Salgame, and Sabine Ehrt

Nucleotide-Binding Oligomerization Domain Protein 2-Deficient Mice Control Infection with Mycobacterium tuberculosis
Infect. Immun. 2007 75: 5127-5134. [Abstract] [Full Text] [PDF]  

Laetitia Breuilh, François Vanhoutte, Josette Fontaine, Caroline M. W. van Stijn, Isabelle Tillie-Leblond, Monique Capron, Christelle Faveeuw, Thierry Jouault, Irma van Die, Philippe Gosset, and François Trottein

Galectin-3 Modulates Immune and Inflammatory Responses during Helminthic Infection: Impact of Galectin-3 Deficiency on the Functions of Dendritic Cells
Infect. Immun. 2007 75: 5148-5157. [Abstract] [Full Text] [PDF]  

Jan Andersson, Arina Samarina, Joshua Fink, Sayma Rahman, and Susanna Grundström

Impaired Expression of Perforin and Granulysin in CD8⁺ T Cells at the Site of Infection in Human Chronic Pulmonary Tuberculosis
Infect. Immun. 2007 75: 5210-5222. [Abstract] [Full Text] [PDF]  

Koh Tomimori, Eriko Uema, Hiromitsu Teruya, Chie Ishikawa, Taeko Okudaira, Masachika Senba, Kazuo Yamamoto, Toshifumi Matsuyama, Fukunori Kinjo, Jiro Fujita, and Naoki Mori

Helicobacter pylori Induces CCL20 Expression
Infect. Immun. 2007 75: 5223-5232. [Abstract] [Full Text] [PDF]  

Pablo Schierloh, Noemí Yokobori, Mercedes Alemán, Verónica Landoni, Laura Geffner, Rosa M. Musella, Jorge Castagnino, Matias Baldini, Eduardo Abbate, Silvia S. de la Barrera, and María C. Sasiain

Mycobacterium tuberculosis-Induced Gamma Interferon Production by Natural Killer Cells Requires Cross Talk with Antigen-Presenting Cells Involving Toll-Like Receptors 2 and 4 and the Mannose Receptor in Tuberculous Pleurisy
Infect. Immun. 2007 75: 5325-5337. [Abstract] [Full Text] [PDF]  

Kee-Jong Hong, Jason R. Wickstrum, Hung-Wen Yeh, and Michael J. Parmely

Toll-Like Receptor 2 Controls the Gamma Interferon Response to Francisella tularensis by Mouse Liver Lymphocytes
Infect. Immun. 2007 75: 5338-5345. [Abstract] [Full Text] [PDF]  

Bruce D. McCollister, Jesse T. Myers, Jessica Jones-Carson, Dennis R. Voelker, and Andrés Vázquez-Torres

Constitutive Acid Sphingomyelinase Enhances Early and Late Macrophage Killing of Salmonella enterica Serovar Typhimurium
Infect. Immun. 2007 75: 5346-5352. [Abstract] [Full Text] [PDF]  

Benjamin K. Billips, Sarah G. Forrestal, Matthew T. Rycyk, James R. Johnson, David J. Klumpp, and Anthony J. Schaeffer

Modulation of Host Innate Immune Response in the Bladder by Uropathogenic Escherichia coli
Infect. Immun. 2007 75: 5353-5360. [Abstract] [Full Text] [PDF]  

Jean-François Gauthier, Andrée Fortin, Yves Bergeron, Marie-Christine Dumas, Marie-Eve Champagne, and Michel G. Bergeron

Differential Contribution of Bacterial N-Formyl-Methionyl-Leucyl- Phenylalanine and Host-Derived CXC Chemokines to Neutrophil Infiltration into Pulmonary Alveoli during Murine Pneumococcal Pneumonia
Infect. Immun. 2007 75: 5361-5367. [Abstract] [Full Text] [PDF]  

Molly K. McLendon, Birgit Schilling, Jason R. Hunt, Michael A. Apicella, and Bradford W. Gibson

Identification of LpxL, a Late Acyltransferase of Francisella tularensis
Infect. Immun. 2007 75: 5518-5531. [Abstract] [Full Text] [PDF] [Supplemental material]  

Molecular Pathogenesis:

Pamela Schnupf, Jianmin Zhou, Alexander Varshavsky, and Daniel A. Portnoy

Listeriolysin O Secreted by Listeria monocytogenes into the Host Cell Cytosol Is Degraded by the N-End Rule Pathway
Infect. Immun. 2007 75: 5135-5147. [Abstract] [Full Text] [PDF]  

Janny Liautard, Safia Ouahrani-Bettache, Véronique Jubier-Maurin, Virginie Lafont, Stephan Köhler, and Jean-Pierre Liautard

Identification and Isolation of Brucella suis Virulence Genes Involved in Resistance to the Human Innate Immune System
Infect. Immun. 2007 75: 5167-5174. [Abstract] [Full Text] [PDF]  

Mahtab Moayeri, Jason F. Wiggins, and Stephen H. Leppla

Anthrax Protective Antigen Cleavage and Clearance from the Blood of Mice and Rats
Infect. Immun. 2007 75: 5175-5184. [Abstract] [Full Text] [PDF]  

Yan Zhuang, James E. Futse, Wendy C. Brown, Kelly A. Brayton, and Guy H. Palmer

Maintenance of Antibody to Pathogen Epitopes Generated by Segmental Gene Conversion Is Highly Dynamic during Long-Term Persistent Infection
Infect. Immun. 2007 75: 5185-5190. [Abstract] [Full Text] [PDF] [Supplemental material]  

James T. Paulley, Eric S. Anderson, and R. Martin Roop, II

Brucella abortus Requires the Heme Transporter BhuA for Maintenance of Chronic Infection in BALB/c Mice
Infect. Immun. 2007 75: 5248-5254. [Abstract] [Full Text] [PDF]  

Christine M. Litwin, Mindy L. Rawlins, and Erica M. Swenson

Characterization of an Immunogenic Outer Membrane Autotransporter Protein, Arp, of Bartonella henselae
Infect. Immun. 2007 75: 5255-5263. [Abstract] [Full Text] [PDF]  

Chantal Forest, Sébastien P. Faucher, Katherine Poirier, Sébastien Houle, Charles M. Dozois, and France Daigle

Contribution of the stg Fimbrial Operon of Salmonella enterica Serovar Typhi during Interaction with Human Cells
Infect. Immun. 2007 75: 5264-5271. [Abstract] [Full Text] [PDF]  

Elizabeth A. Rogers and Richard T. Marconi

Delineation of Species-Specific Binding Properties of the CspZ Protein (BBH06) of Lyme Disease Spirochetes: Evidence for New Contributions to the Pathogenesis of Borrelia spp.
Infect. Immun. 2007 75: 5272-5281. [Abstract] [Full Text] [PDF]  

Tamara M. Maier, Monika S. Casey, Rachel H. Becker, Caleb W. Dorsey, Elizabeth M. Glass, Natalia Maltsev, Thomas C. Zahrt, and Dara W. Frank

Identification of Francisella tularensis Himar1-Based Transposon Mutants Defective for Replication in Macrophages
Infect. Immun. 2007 75: 5376-5389. [Abstract] [Full Text] [PDF]  

Laurent Hébert, Pascal Courtin, Riccardo Torelli, Maurizio Sanguinetti, Marie-Pierre Chapot-Chartier, Yanick Auffray, and Abdellah Benachour

Enterococcus faecalis Constitutes an Unusual Bacterial Model in Lysozyme Resistance
Infect. Immun. 2007 75: 5390-5398. [Abstract] [Full Text] [PDF]  

Kelvin D. Kemp, Kavindra V. Singh, Sreedhar R. Nallapareddy, and Barbara E. Murray

Relative Contributions of Enterococcus faecalis OG1RF Sortase-Encoding Genes, srtA and bps (srtC), to Biofilm Formation and a Murine Model of Urinary Tract Infection
Infect. Immun. 2007 75: 5399-5404. [Abstract] [Full Text] [PDF] [Supplemental material]  

Ulrike Samen, Bernhard J. Eikmanns, Dieter J. Reinscheid, and Frédéric Borges

The Surface Protein Srr-1 of Streptococcus agalactiae Binds Human Keratin 4 and Promotes Adherence to Epithelial HEp-2 Cells
Infect. Immun. 2007 75: 5405-5414. [Abstract] [Full Text] [PDF]  

Guangchun Bai, Michaela A. Gazdik, Damen D. Schaak, and Kathleen A. McDonough

The Mycobacterium bovis BCG Cyclic AMP Receptor-Like Protein Is a Functional DNA Binding Protein In Vitro and In Vivo, but Its Activity Differs from That of Its M. tuberculosis Ortholog, Rv3676
Infect. Immun. 2007 75: 5509-5517. [Abstract] [Full Text] [PDF]  

Bacterial Infections:

Gillian D. Pullinger, Susan M. Paulin, Bryan Charleston, Patricia R. Watson, Alison J. Bowen, Francis Dziva, Eirwen Morgan, Bernardo Villarreal-Ramos, Timothy S. Wallis, and Mark P. Stevens

Systemic Translocation of Salmonella enterica Serovar Dublin in Cattle Occurs Predominantly via Efferent Lymphatics in a Cell-Free Niche and Requires Type III Secretion System 1 (T3SS-1) but Not T3SS-2
Infect. Immun. 2007 75: 5191-5199. [Abstract] [Full Text] [PDF]  

Trupti N. Brahmbhatt, Brian K. Janes, E. Scott Stibitz, Stephen C. Darnell, Patrick Sanz, Susan B. Rasmussen, and Alison D. O'Brien

Bacillus anthracis Exosporium Protein BclA Affects Spore Germination, Interaction with Extracellular Matrix Proteins, and Hydrophobicity
Infect. Immun. 2007 75: 5233-5239. [Abstract] [Full Text] [PDF]  

Malcolm S. Duthie, Stephen T. Reece, Ramanuj Lahiri, Wakako Goto, Vanitha S. Raman, Juliette Kaplan, Greg C. Ireton, Sylvie Bertholet, Thomas P. Gillis, James L. Krahenbuhl, and Steven G. Reed

Antigen-Specific Cellular and Humoral Responses Are Induced by Intradermal Mycobacterium leprae Infection of the Mouse Ear
Infect. Immun. 2007 75: 5290-5297. [Abstract] [Full Text] [PDF]  

Andrew T. Anfora, Brian J. Haugen, Paula Roesch, Peter Redford, and Rodney A. Welch

Roles of Serine Accumulation and Catabolism in the Colonization of the Murine Urinary Tract by Escherichia coli CFT073
Infect. Immun. 2007 75: 5298-5304. [Abstract] [Full Text] [PDF]  

Timothy J. Brickman and Sandra K. Armstrong

Impact of Alcaligin Siderophore Utilization on In Vivo Growth of Bordetella pertussis
Infect. Immun. 2007 75: 5305-5312. [Abstract] [Full Text] [PDF]  

Mike S. Son, Wallace J. Matthews, Jr., Yun Kang, David T. Nguyen, and Tung T. Hoang

In Vivo Evidence of Pseudomonas aeruginosa Nutrient Acquisition and Pathogenesis in the Lungs of Cystic Fibrosis Patients
Infect. Immun. 2007 75: 5313-5324. [Abstract] [Full Text] [PDF] [Supplemental material]  

Shalaka Metkar, Shanjana Awasthi, Erick Denamur, Kwang Sik Kim, Sophie C. Gangloff, Saul Teichberg, Alain Haziot, Jack Silver, and Sanna M. Goyert

Role of CD14 in Responses to Clinical Isolates of Escherichia coli: Effects of K1 Capsule Expression
Infect. Immun. 2007 75: 5415-5424. [Abstract] [Full Text] [PDF]  

Steven M. Autieri, Jeremy J. Lins, Mary P. Leatham, David C. Laux, Tyrrell Conway, and Paul S. Cohen

L-Fucose Stimulates Utilization of D-Ribose by Escherichia coli MG1655 fucAO and E. coli Nissle 1917 fucAO Mutants in the Mouse Intestine and in M9 Minimal Medium
Infect. Immun. 2007 75: 5465-5475. [Abstract] [Full Text] [PDF]  

Microbial Immunity and Vaccines:

Trupti N. Brahmbhatt, Stephen C. Darnell, Humberto M. Carvalho, Patrick Sanz, Tae J. Kang, Robert L. Bull, Susan B. Rasmussen, Alan S. Cross, and Alison D. O'Brien

Recombinant Exosporium Protein BclA of Bacillus anthracis Is Effective as a Booster for Mice Primed with Suboptimal Amounts of Protective Antigen
Infect. Immun. 2007 75: 5240-5247. [Abstract] [Full Text] [PDF]  

James A. Triccas, Elena Shklovskaya, Joanne Spratt, Anthony A. Ryan, Umaimainthan Palendira, Barbara Fazekas de StGroth, and Warwick J. Britton

Effects of DNA- and Mycobacterium bovis BCG-Based Delivery of the Flt3 Ligand on Protective Immunity to Mycobacterium tuberculosis
Infect. Immun. 2007 75: 5368-5375. [Abstract] [Full Text] [PDF]  

Mark T. Albrecht, Han Li, E. Diane Williamson, Chris S. LeButt, Helen C. Flick-Smith, Conrad P. Quinn, Hans Westra, Darrell Galloway, Alfred Mateczun, Stanley Goldman, Herman Groen, and Les W. J. Baillie

Human Monoclonal Antibodies against Anthrax Lethal Factor and Protective Antigen Act Independently To Protect against Bacillus anthracis Infection and Enhance Endogenous Immunity to Anthrax
Infect. Immun. 2007 75: 5425-5433. [Abstract] [Full Text] [PDF]  

Vincent E. Weynants, Christiane M. Feron, Karine K. Goraj, Martine P. Bos, Philippe A. Denoël, Vincent G. Verlant, Jan Tommassen, Ian R. A. Peak, Ralph C. Judd, Michael P. Jennings, and Jan T. Poolman

Additive and Synergistic Bactericidal Activity of Antibodies Directed against Minor Outer Membrane Proteins of Neisseria meningitidis
Infect. Immun. 2007 75: 5434-5442. [Abstract] [Full Text] [PDF]  

Herman F. Staats, S. Munir Alam, Richard M. Scearce, Shaun M. Kirwan, Julia Xianzhi Zhang, William M. Gwinn, and Barton F. Haynes

In Vitro and In Vivo Characterization of Anthrax Anti-Protective Antigen and Anti-Lethal Factor Monoclonal Antibodies after Passive Transfer in a Mouse Lethal Toxin Challenge Model To Define Correlates of Immunity
Infect. Immun. 2007 75: 5443-5452. [Abstract] [Full Text] [PDF]  

Bisweswar Nandi, Kathryn Hogle, Nicholas Vitko, and Gary M. Winslow

CD4 T-Cell Epitopes Associated with Protective Immunity Induced following Vaccination of Mice with an Ehrlichial Variable Outer Membrane Protein
Infect. Immun. 2007 75: 5453-5459. [Abstract] [Full Text] [PDF] [Supplemental material]  

Alan Basset, Claudette M. Thompson, Susan K. Hollingshead, David E. Briles, Edwin W. Ades, Marc Lipsitch, and Richard Malley

Antibody-Independent, CD4⁺ T-Cell-Dependent Protection against Pneumococcal Colonization Elicited by Intranasal Immunization with Purified Pneumococcal Proteins
Infect. Immun. 2007 75: 5460-5464. [Abstract] [Full Text] [PDF]  

Ahmad H. Hussein, Elisabeth M. Davis, Scott A. Halperin, and Song F. Lee

Construction and Characterization of Single-Chain Variable Fragment Antibodies Directed against the Bordetella pertussis Surface Adhesins Filamentous Hemagglutinin and Pertactin
Infect. Immun. 2007 75: 5476-5482. [Abstract] [Full Text] [PDF]  

Molecular Genomics:

L. P. N. Tuchscherr, M. I. Gomez, F. R. Buzzola, L. F. Calvinho, J. C. Lee, and D. O. Sordelli

Characterization of a New Variant of IS257 That Has Displaced the Capsule Genes within Bovine Isolates of Staphylococcus aureus
Infect. Immun. 2007 75: 5483-5488. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.