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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
Infect. Immun. 2007 75: 1065. [Full Text] [PDF]  

Minireviews:

Mahalia S. Desruisseaux, Nagajyothi, Maria E. Trujillo, Herbert B. Tanowitz, and Philipp E. Scherer

Adipocyte, Adipose Tissue, and Infectious Disease
Infect. Immun. 2007 75: 1066-1078. [Full Text] [PDF]  

Molecular Pathogenesis:

Patrick H. Tu Quoc, Pierre Genevaux, Maria Pajunen, Harri Savilahti, Costa Georgopoulos, Jacques Schrenzel, and William L. Kelley

Isolation and Characterization of Biofilm Formation-Defective Mutants of Staphylococcus aureus
Infect. Immun. 2007 75: 1079-1088. [Abstract] [Full Text] [PDF]  

Vincent T. Lee, Stefan Pukatzki, Hiromi Sato, Eriya Kikawada, Anastasia A. Kazimirova, Jin Huang, Xiaohua Li, Jonathan P. Arm, Dara W. Frank, and Stephen Lory

Pseudolipasin A Is a Specific Inhibitor for Phospholipase A₂ Activity of Pseudomonas aeruginosa Cytotoxin ExoU
Infect. Immun. 2007 75: 1089-1098. [Abstract] [Full Text] [PDF] [Supplemental material]  

Julio Hernandez, Andrew Lackner, Pyone Aye, Kakali Mukherjee, David J. Tweardy, Mary-Ann Mastrangelo, Joel Weinstock, Jeffrey Griffiths, Melinda D'Souza, Shantu Dixit, and Prema Robinson

Substance P Is Responsible for Physiological Alterations Such as Increased Chloride Ion Secretion and Glucose Malabsorption in Cryptosporidiosis
Infect. Immun. 2007 75: 1137-1143. [Abstract] [Full Text] [PDF]  

J. Cuccui, A. Easton, K. K. Chu, G. J. Bancroft, P. C. F. Oyston, R. W. Titball, and B. W. Wren

Development of Signature-Tagged Mutagenesis in Burkholderia pseudomallei To Identify Genes Important in Survival and Pathogenesis
Infect. Immun. 2007 75: 1186-1195. [Abstract] [Full Text] [PDF]  

Peggy C. R. Godschalk, Mark L. Kuijf, Jianjun Li, Frank St. Michael, C. Wim Ang, Bart C. Jacobs, Marie-France Karwaski, Denis Brochu, Ali Moterassed, Hubert P. Endtz, Alex van Belkum, and Michel Gilbert

Structural Characterization of Campylobacter jejuni Lipooligosaccharide Outer Cores Associated with Guillain-Barré and Miller Fisher Syndromes
Infect. Immun. 2007 75: 1245-1254. [Abstract] [Full Text] [PDF] [Supplemental material]  

Beth A. Lowe, Jesse D. Miller, and Melody N. Neely

Analysis of the Polysaccharide Capsule of the Systemic Pathogen Streptococcus iniae and Its Implications in Virulence
Infect. Immun. 2007 75: 1255-1264. [Abstract] [Full Text] [PDF]  

Javier Santander, Soo-Young Wanda, Cheryl A. Nickerson, and Roy Curtiss, III

Role of RpoS in Fine-Tuning the Synthesis of Vi Capsular Polysaccharide in Salmonella enterica Serotype Typhi
Infect. Immun. 2007 75: 1382-1392. [Abstract] [Full Text] [PDF]  

Rishi D. Pathirana, Neil M. O'Brien-Simpson, Gail C. Brammar, Nada Slakeski, and Eric C. Reynolds

Kgp and RgpB, but Not RgpA, Are Important for Porphyromonas gingivalis Virulence in the Murine Periodontitis Model
Infect. Immun. 2007 75: 1436-1442. [Abstract] [Full Text] [PDF]  

Mariano E. Fernandez-Miyakawa, Derek J. Fisher, Rachael Poon, Sameera Sayeed, Vicki Adams, Julian I. Rood, Bruce A. McClane, and Francisco A. Uzal

Both Epsilon-Toxin and Beta-Toxin Are Important for the Lethal Properties of Clostridium perfringens Type B Isolates in the Mouse Intravenous Injection Model
Infect. Immun. 2007 75: 1443-1452. [Abstract] [Full Text] [PDF]  

Atul K. Johri, Immaculada Margarit, Mark Broenstrup, Cecilia Brettoni, Lei Hua, Steven P. Gygi, John L. Telford, Guido Grandi, and Lawrence C. Paoletti

Transcriptional and Proteomic Profiles of Group B Streptococcus Type V Reveal Potential Adherence Proteins Associated with High-Level Invasion
Infect. Immun. 2007 75: 1473-1483. [Abstract] [Full Text] [PDF]  

Camino Pérez-Gutiérrez, Catalina M. Llompart, Mikael Skurnik, and José A. Bengoechea

Expression of the Yersinia enterocolitica pYV-Encoded Type III Secretion System Is Modulated by Lipopolysaccharide O-Antigen Status
Infect. Immun. 2007 75: 1512-1516. [Abstract] [Full Text] [PDF]  

Kit Tilly, Aaron Bestor, Mollie W. Jewett, and Patricia Rosa

Rapid Clearance of Lyme Disease Spirochetes Lacking OspC from Skin
Infect. Immun. 2007 75: 1517-1519. [Abstract] [Full Text] [PDF]  

Eirwen Morgan, Alison J. Bowen, Sonya C. Carnell, Timothy S. Wallis, and Mark P. Stevens

SiiE Is Secreted by the Salmonella enterica Serovar Typhimurium Pathogenicity Island 4-Encoded Secretion System and Contributes to Intestinal Colonization in Cattle
Infect. Immun. 2007 75: 1524-1533. [Abstract] [Full Text] [PDF]  

Adam J. Potter, Stephen P. Kidd, Michael P. Jennings, and Alastair G. McEwan

Evidence for Distinctive Mechanisms of S-Nitrosoglutathione Metabolism by AdhC in Two Closely Related Species, Neisseria gonorrhoeae and Neisseria meningitidis
Infect. Immun. 2007 75: 1534-1536. [Abstract] [Full Text] [PDF]  

Bacterial Infections:

L. S. Mansfield, J. A. Bell, D. L. Wilson, A. J. Murphy, H. M. Elsheikha, V. A. K. Rathinam, B. R. Fierro, J. E. Linz, and V. B. Young

C57BL/6 and Congenic Interleukin-10-Deficient Mice Can Serve as Models of Campylobacter jejuni Colonization and Enteritis
Infect. Immun. 2007 75: 1099-1115. [Abstract] [Full Text] [PDF]  

Corine A. N. Broekhuizen, Leonie de Boer, Kim Schipper, Christopher D. Jones, Shan Quadir, Roger G. Feldman, Jacob Dankert, Christina M. J. E. Vandenbroucke-Grauls, Jan J. Weening, and Sebastian A. J. Zaat

Peri-Implant Tissue Is an Important Niche for Staphylococcus epidermidis in Experimental Biomaterial-Associated Infection in Mice
Infect. Immun. 2007 75: 1129-1136. [Abstract] [Full Text] [PDF]  

Keer Sun, Sharon L. Salmon, Steven A. Lotz, and Dennis W. Metzger

Interleukin-12 Promotes Gamma Interferon-Dependent Neutrophil Recruitment in the Lung and Improves Protection against Respiratory Streptococcus pneumoniae Infection
Infect. Immun. 2007 75: 1196-1202. [Abstract] [Full Text] [PDF]  

Masahiko Nakamura, Somay Yamagata Murayama, Hiroshi Serizawa, Yukie Sekiya, Masahiro Eguchi, Shinichi Takahashi, Kaori Nishikawa, Tetsufumi Takahashi, Tsukasa Matsumoto, Haruki Yamada, Toshifumi Hibi, Kanji Tsuchimoto, and Hidenori Matsui

"Candidatus Helicobacter heilmannii" from a Cynomolgus Monkey Induces Gastric Mucosa-Associated Lymphoid Tissue Lymphomas in C57BL/6 Mice
Infect. Immun. 2007 75: 1214-1222. [Abstract] [Full Text] [PDF]  

Agnès Rosenau, Karine Martins, Souheila Amor, François Gannier, Philippe Lanotte, Nathalie van der Mee-Marquet, Laurent Mereghetti, and Roland Quentin

Evaluation of the Ability of Streptococcus agalactiae Strains Isolated from Genital and Neonatal Specimens To Bind to Human Fibrinogen and Correlation with Characteristics of the fbsA and fbsB Genes
Infect. Immun. 2007 75: 1310-1317. [Abstract] [Full Text] [PDF]  

Rachel M. Exley, Hong Wu, Jonathan Shaw, Muriel C. Schneider, Harry Smith, Ann E. Jerse, and Christoph M. Tang

Lactate Acquisition Promotes Successful Colonization of the Murine Genital Tract by Neisseria gonorrhoeae
Infect. Immun. 2007 75: 1318-1324. [Abstract] [Full Text] [PDF]  

Matthew S. Lawlor, Christopher O'Connor, and Virginia L. Miller

Yersiniabactin Is a Virulence Factor for Klebsiella pneumoniae during Pulmonary Infection
Infect. Immun. 2007 75: 1463-1472. [Abstract] [Full Text] [PDF]  

Guy H. Palmer, James E. Futse, Christina K. Leverich, Donald P. Knowles, Jr., Fred R. Rurangirwa, and Kelly A. Brayton

Selection for Simple Major Surface Protein 2 Variants during Anaplasma marginale Transmission to Immunologically Naïve Animals
Infect. Immun. 2007 75: 1502-1506. [Abstract] [Full Text] [PDF]  

Elizabeth M. Fozo, Kathy Scott-Anne, Hyun Koo, and Robert G. Quivey, Jr.

Role of Unsaturated Fatty Acid Biosynthesis in Virulence of Streptococcus mutans
Infect. Immun. 2007 75: 1537-1539. [Abstract] [Full Text] [PDF]  

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions:

Kevin D. Augustijn, Robert Kleemann, Joanne Thompson, Teake Kooistra, Carina E. Crawford, Sarah E. Reece, Arnab Pain, Arjan H. G. Siebum, Chris J. Janse, and Andrew P Waters

Functional Characterization of the Plasmodium falciparum and P. berghei Homologues of Macrophage Migration Inhibitory Factor
Infect. Immun. 2007 75: 1116-1128. [Abstract] [Full Text] [PDF]  

Kevin M. Bourzac, Crystal M. Botham, and Karen Guillemin

Helicobacter pylori CagA Induces AGS Cell Elongation through a Cell Retraction Defect That Is Independent of Cdc42, Rac1, and Arp2/3
Infect. Immun. 2007 75: 1203-1213. [Abstract] [Full Text] [PDF] [Supplemental material]  

X. Vega-Manriquez, Y. López-Vidal, J. Moran, L. G. Adams, and J. A. Gutiérrez-Pabello

Apoptosis-Inducing Factor Participation in Bovine Macrophage Mycobacterium bovis-Induced Caspase-Independent Cell Death
Infect. Immun. 2007 75: 1223-1228. [Abstract] [Full Text] [PDF]  

Mark P. Simons, Jill M. Moore, Troy J. Kemp, and Thomas S. Griffith

Identification of the Mycobacterial Subcomponents Involved in the Release of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand from Human Neutrophils
Infect. Immun. 2007 75: 1265-1271. [Abstract] [Full Text] [PDF]  

Estela M. Galván, Huaiqing Chen, and Dieter M. Schifferli

The Psa Fimbriae of Yersinia pestis Interact with Phosphatidylcholine on Alveolar Epithelial Cells and Pulmonary Surfactant
Infect. Immun. 2007 75: 1272-1279. [Abstract] [Full Text] [PDF]  

Wilbert A. Derbigny, Soon-Cheol Hong, Micah S. Kerr, M'hamed Temkit, and Raymond M. Johnson

Chlamydia muridarum Infection Elicits a Beta Interferon Response in Murine Oviduct Epithelial Cells Dependent on Interferon Regulatory Factor 3 and TRIF
Infect. Immun. 2007 75: 1280-1290. [Abstract] [Full Text] [PDF]  

Sang-Yun Lee, Rama P. Cherla, and Vernon L. Tesh

Simultaneous Induction of Apoptotic and Survival Signaling Pathways in Macrophage-Like THP-1 Cells by Shiga Toxin 1
Infect. Immun. 2007 75: 1291-1302. [Abstract] [Full Text] [PDF]  

Helena Lindgren, Hua Shen, Carl Zingmark, Igor Golovliov, Wayne Conlan, and Anders Sjöstedt

Resistance of Francisella tularensis Strains against Reactive Nitrogen and Oxygen Species with Special Reference to the Role of KatG
Infect. Immun. 2007 75: 1303-1309. [Abstract] [Full Text] [PDF]  

Takao Kitagawa, Hisashi Hoshida, and Rinji Akada

Genome-Wide Analysis of Cellular Response to Bacterial Genotoxin CdtB in Yeast
Infect. Immun. 2007 75: 1393-1402. [Abstract] [Full Text] [PDF] [Supplemental material]  

Host Response and Inflammation:

Tao Wang, Linhua Tian, Makoto Haino, Ji-Liang Gao, Ross Lake, Yvona Ward, Hongshan Wang, Ulrich Siebenlist, Philip M. Murphy, and Kathleen Kelly

Improved Antibacterial Host Defense and Altered Peripheral Granulocyte Homeostasis in Mice Lacking the Adhesion Class G Protein Receptor CD97
Infect. Immun. 2007 75: 1144-1153. [Abstract] [Full Text] [PDF]  

Laura H. Hogan, Dominic O. Co, Jozsef Karman, Erika Heninger, M. Suresh, and Matyas Sandor

Virally Activated CD8 T Cells Home to Mycobacterium bovis BCG-Induced Granulomas but Enhance Antimycobacterial Protection Only in Immunodeficient Mice
Infect. Immun. 2007 75: 1154-1166. [Abstract] [Full Text] [PDF]  

Shu-Rung Chang, Kung-Jiun Wang, Yan-Feng Lu, Lii-Jia Yang, Wei-Jie Chen, Yu-Hsiang Lin, Hsin-Hou Chang, and Shih-Lien Wang

Characterization of Early Gamma Interferon (IFN-) Expression during Murine Listeriosis: Identification of NK1.1⁺ CD11c⁺ Cells as the Primary IFN--Expressing Cells
Infect. Immun. 2007 75: 1167-1176. [Abstract] [Full Text] [PDF]  

Tiffany R. Keepers, Lisa K. Gross, and Tom G. Obrig

Monocyte Chemoattractant Protein 1, Macrophage Inflammatory Protein 1, and RANTES Recruit Macrophages to the Kidney in a Mouse Model of Hemolytic-Uremic Syndrome
Infect. Immun. 2007 75: 1229-1236. [Abstract] [Full Text] [PDF]  

Gordon B. Mitchell, Muthafar H. Al-Haddawi, Mary Ellen Clark, Jennifer D. Beveridge, and Jeff L. Caswell

Effect of Corticosteroids and Neuropeptides on the Expression of Defensins in Bovine Tracheal Epithelial Cells
Infect. Immun. 2007 75: 1325-1334. [Abstract] [Full Text] [PDF]  

Jason R. Wickstrum, Kee-Jong Hong, Sirosh Bokhari, Natalie Reed, Nicholas McWilliams, Rebecca T. Horvat, and Michael J. Parmely

Coactivating Signals for the Hepatic Lymphocyte Gamma Interferon Response to Francisella tularensis
Infect. Immun. 2007 75: 1335-1342. [Abstract] [Full Text] [PDF]  

Anatoly N. Mikerov, Guirong Wang, Todd M. Umstead, Mario Zacharatos, Neal J. Thomas, David S. Phelps, and Joanna Floros

Surfactant Protein A2 (SP-A2) Variants Expressed in CHO Cells Stimulate Phagocytosis of Pseudomonas aeruginosa More than Do SP-A1 Variants
Infect. Immun. 2007 75: 1403-1412. [Abstract] [Full Text] [PDF]  

Andrea Dorfleutner, Nicole B. Bryan, Siera J. Talbott, Kristin N. Funya, Stephanie L. Rellick, John C. Reed, Xianglin Shi, Yon Rojanasakul, Daniel C. Flynn, and Christian Stehlik

Cellular Pyrin Domain-Only Protein 2 Is a Candidate Regulator of Inflammasome Activation
Infect. Immun. 2007 75: 1484-1492. [Abstract] [Full Text] [PDF]  

Heloisa D'Ávila, Patrícia E. Almeida, Natália R. Roque, Hugo C. Castro-Faria-Neto, and Patrícia T. Bozza

Toll-Like Receptor-2-Mediated C-C Chemokine Receptor 3 and Eotaxin-Driven Eosinophil Influx Induced by Mycobacterium bovis BCG Pleurisy
Infect. Immun. 2007 75: 1507-1511. [Abstract] [Full Text] [PDF]  

Kenta Maruyama, Gen-ichiro Sano, Neelanjan Ray, Yasunari Takada, and Koichi Matsuo

c-Fos-Deficient Mice Are Susceptible to Salmonella enterica Serovar Typhimurium Infection
Infect. Immun. 2007 75: 1520-1523. [Abstract] [Full Text] [PDF]  

Fungal and Parasitic Infections:

Anjali Yadava, Jetsumon Sattabongkot, Michael A. Washington, Lisa A. Ware, Victoria Majam, Hong Zheng, Sanjai Kumar, and Christian F. Ockenhouse

A Novel Chimeric Plasmodium vivax Circumsporozoite Protein Induces Biologically Functional Antibodies That Recognize both VK210 and VK247 Sporozoites
Infect. Immun. 2007 75: 1177-1185. [Abstract] [Full Text] [PDF]  

Felicitas Schöbel, Oumaïma Ibrahim-Granet, Patrick Avé, Jean-Paul Latgé, Axel A. Brakhage, and Matthias Brock

Aspergillus fumigatus Does Not Require Fatty Acid Metabolism via Isocitrate Lyase for Development of Invasive Aspergillosis
Infect. Immun. 2007 75: 1237-1244. [Abstract] [Full Text] [PDF]  

D. J. L. Williams, C. S. Guy, R. F. Smith, J. Ellis, C. Björkman, M. P. Reichel, and A. J. Trees

Immunization of Cattle with Live Tachyzoites of Neospora caninum Confers Protection against Fetal Death
Infect. Immun. 2007 75: 1343-1348. [Abstract] [Full Text] [PDF]  

Qifang Shi, Michelle M. Lynch, Margarita Romero, and James M. Burns, Jr.

Enhanced Protection against Malaria by a Chimeric Merozoite Surface Protein Vaccine
Infect. Immun. 2007 75: 1349-1358. [Abstract] [Full Text] [PDF]  

David O. Beenhouwer, Esther M. Yoo, Chun-Wei Lai, Miguel A. Rocha, and Sherie L. Morrison

Human Immunoglobulin G2 (IgG2) and IgG4, but Not IgG1 or IgG3, Protect Mice against Cryptococcus neoformans Infection
Infect. Immun. 2007 75: 1424-1435. [Abstract] [Full Text] [PDF]  

Floyd L. Wormley, Jr., John R. Perfect, Chad Steele, and Gary M. Cox

Protection against Cryptococcosis by Using a Murine Gamma Interferon-Producing Cryptococcus neoformans Strain
Infect. Immun. 2007 75: 1453-1462. [Abstract] [Full Text] [PDF]  

Chantal Fradin, Abigail L. Mavor, Günther Weindl, Martin Schaller, Karin Hanke, Stefan H. E. Kaufmann, Hans Mollenkopf, and Bernhard Hube

The Early Transcriptional Response of Human Granulocytes to Infection with Candida albicans Is Not Essential for Killing but Reflects Cellular Communications
Infect. Immun. 2007 75: 1493-1501. [Abstract] [Full Text] [PDF]  

Microbial Immunity and Vaccines:

Stefan Fernandez, Dupeh R. Palmer, Monika Simmons, Peifang Sun, John Bisbing, Sasha McClain, Sachin Mani, Timothy Burgess, Vicky Gunther, and Wellington Sun

Potential Role for Toll-Like Receptor 4 in Mediating Escherichia coli Maltose-Binding Protein Activation of Dendritic Cells
Infect. Immun. 2007 75: 1359-1363. [Abstract] [Full Text] [PDF]  

Jeannette N. Williams, Paul J. Skipp, Holly E. Humphries, Myron Christodoulides, C. David O'Connor, and John E. Heckels

Proteomic Analysis of Outer Membranes and Vesicles from Wild-Type Serogroup B Neisseria meningitidis and a Lipopolysaccharide-Deficient Mutant
Infect. Immun. 2007 75: 1364-1372. [Abstract] [Full Text] [PDF] [Supplemental material]  

Robin J. Flynn, Celine Mannion, Olwen Golden, Orcun Hacariz, and Grace Mulcahy

Experimental Fasciola hepatica Infection Alters Responses to Tests Used for Diagnosis of Bovine Tuberculosis
Infect. Immun. 2007 75: 1373-1381. [Abstract] [Full Text] [PDF]  

Sergio Arce, Hesham F. Nawar, Gwendolin Muehlinghaus, Michael W. Russell, and Terry D. Connell

In Vitro Induction of Immunoglobulin A (IgA)- and IgM-Secreting Plasma Blasts by Cholera Toxin Depends on T-Cell Help and Is Mediated by CD154 Up-Regulation and Inhibition of Gamma Interferon Synthesis
Infect. Immun. 2007 75: 1413-1423. [Abstract] [Full Text] [PDF]  

Author's Correction:

Laura E. Swaim, Lynn E. Connolly, Hannah E. Volkman, Olivier Humbert, Donald E. Born, and Lalita Ramakrishnan

Mycobacterium marinum Infection of Adult Zebrafish Causes Caseating Granulomatous Tuberculosis and Is Moderated by Adaptive Immunity
Infect. Immun. 2007 75: 1540. [Full Text] [PDF]  

Kiichi Yamamoto, Reiko Ito, Minako Koura, and Tsuneo Kamiyama

UV-B Irradiation Increases Susceptibility of Mice to Malarial Infection
Infect. Immun. 2007 75: 1541. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.