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Cover photograph (Copyright © 2009, American Society for Microbiology. All Rights Reserved.): Preexposure and adaptation of uropathogenic Escherichia coli (reddish brown; imaged by transmission electron microscopy) promote enhanced bacterial colonization of the bladder. The background of this composite image shows the apical surface of the mouse urothelium stained with the fluorescent nuclear dye Hoechst, which highlights the hexagonal, binucleate superficial facet cells of the bladder. (Image by R. R. Kulesus and M. A. Mulvey.) (See related article on p. 2104.)


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