Table of Contents

December 1, 1998; Volume 66,Issue 12

Molecular and Cellular Pathogenesis

MOLECULAR AND CELLULAR PATHOGENESIS
Molecular and Functional Characterization ofSalmonella enterica Serovar Typhimurium poxAGene: Effect on Attenuation of Virulence and Protection
Koné Kaniga, Melissa S. Compton, Roy Curtiss, Preeti Sundaram
MOLECULAR AND CELLULAR PATHOGENESIS
The Lipopolysaccharide of Bordetella bronchiseptica Acts as a Protective Shield against Antimicrobial Peptides
Andreas Banemann, Heike Deppisch, Roy Gross
MOLECULAR AND CELLULAR PATHOGENESIS
Large-Scale Identification of Virulence Genes fromStreptococcus pneumoniae
Alessandra Polissi, Andrea Pontiggia, Georg Feger, Mario Altieri, Harald Mottl, Livia Ferrari, Daniel Simon
MOLECULAR AND CELLULAR PATHOGENESIS
Activity of the Mitogenic Pasteurella multocida Toxin Requires an Essential C-Terminal Residue
Philip N. Ward, Antony J. Miles, Ian G. Sumner, Lewis H. Thomas, Alistair J. Lax
MOLECULAR AND CELLULAR PATHOGENESIS
Sulfatide from the Pig Jejunum Brush Border Epithelial Cell Surface Is Involved in Binding of Escherichia coli Enterotoxin b
Élodie Rousset, Josée Harel, J. Daniel Dubreuil
MOLECULAR AND CELLULAR PATHOGENESIS
The Type IV Leader Peptidase/ N -Methyltransferase ofVibrio vulnificus Controls Factors Required for Adherence to HEp-2 Cells and Virulence in Iron-Overloaded Mice
Rohinee N. Paranjpye, J. Cano Lara, Jeffrey C. Pepe, Cynthia M. Pepe, Mark S. Strom
MOLECULAR AND CELLULAR PATHOGENESIS
Environmental Growth Conditions Influence the Ability of Escherichia coli K1 To Invade Brain Microvascular Endothelial Cells and Confer Serum Resistance
Julie L. Badger, Kwang Sik Kim
MOLECULAR AND CELLULAR PATHOGENESIS
TetR Is a Positive Regulator of the Tetanus Toxin Gene in Clostridium tetani and Is Homologous to BotR
Jean-Christophe Marvaud, Ulrich Eisel, Thomas Binz, Heiner Niemann, Michel R. Popoff
MOLECULAR AND CELLULAR PATHOGENESIS
Cloning, Expression, and Sequencing of a Cell Surface Antigen Containing a Leucine-Rich Repeat Motif from Bacteroides forsythus ATCC 43037
Ashu Sharma, Hakimuddin T. Sojar, Ingrid Glurich, Kiyonobu Honma, Howard K. Kuramitsu, Robert J. Genco
MOLECULAR AND CELLULAR PATHOGENESIS
Brucella abortus Transits through the Autophagic Pathway and Replicates in the Endoplasmic Reticulum of Nonprofessional Phagocytes
Javier Pizarro-Cerdá, Stéphane Méresse, Robert G. Parton, Gisou van der Goot, Alberto Sola-Landa, Ignacio Lopez-Goñi, Edgardo Moreno, Jean-Pierre Gorvel
MOLECULAR AND CELLULAR PATHOGENESIS
Identification and Characterization of a Phase-Variable Nonfimbrial Salmonella typhimurium Gene That Alters O-Antigen Production
Lola Y. Kwan, Richard E. Isaacson
MOLECULAR AND CELLULAR PATHOGENESIS
Flagellins, but Not Endoflagellar Sheath Proteins, of Treponema pallidum and of Pathogen-Related Oral Spirochetes Are Glycosylated
C. Wyss
MOLECULAR AND CELLULAR PATHOGENESIS
Expression of Plasminogen Activator Pla ofYersinia pestis Enhances Bacterial Attachment to the Mammalian Extracellular Matrix
Kaarina Lähteenmäki, Ritva Virkola, Anne Sarén, Levente Emödy, Timo K. Korhonen
MOLECULAR AND CELLULAR PATHOGENESIS
Helicobacter pylori Alters Exogenous Antigen Absorption and Processing in a Digestive Tract Epithelial Cell Line Model
Tamara Matysiak-Budnik, Kathleen Terpend, Sophie Alain, Marie-José Sanson le Pors, Jehan-Francois Desjeux, Francis Mégraud, Martine Heyman
MOLECULAR AND CELLULAR PATHOGENESIS
Secreted Effector Proteins of Salmonella dublin Act in Concert To Induce Enteritis
Michael A. Jones, Michael W. Wood, Paul B. Mullan, Patricia R. Watson, Tim S. Wallis, Edouard E. Galyov
MOLECULAR AND CELLULAR PATHOGENESIS
Analysis of Clinical and Environmental Strains of Nontoxigenic Vibrio cholerae for Susceptibility to CTXΦ: Molecular Basis for Origination of New Strains with Epidemic Potential
Shah M. Faruque, Asadulghani, Manujendra N. Saha, A. R. M. Abdul Alim, M. John Albert, K. M. Nasirul Islam, John J. Mekalanos
MOLECULAR AND CELLULAR PATHOGENESIS
Expression of the pMGA Genes of Mycoplasma gallisepticum Is Controlled by Variation in the GAA Trinucleotide Repeat Lengths within the 5′ Noncoding Regions
Michelle D. Glew, Nina Baseggio, Philip F. Markham, Glenn F. Browning, Ian D. Walker
MOLECULAR AND CELLULAR PATHOGENESIS
Modulation of Expression of the ToxR Regulon in Vibrio cholerae by a Member of the Two-Component Family of Response Regulators
Sandy M. Wong, Patricia A. Carroll, Laurence G. Rahme, Frederick M. Ausubel, Stephen B. Calderwood
MOLECULAR AND CELLULAR PATHOGENESIS
Identification of a 71-Kilodalton Surface-Associated Hsp70 Homologue in Coxiella burnetii
Anna Macellaro, Eva Tujulin, Karin Hjalmarsson, Lena Norlander
MOLECULAR AND CELLULAR PATHOGENESIS
Characterization of Membrane-Associated Clostridium perfringens Enterotoxin following Pronase Treatment
Eva U. Wieckowski, John F. Kokai-Kun, Bruce A. McClane
MOLECULAR AND CELLULAR PATHOGENESIS
Filamentous Hemagglutinin of Bordetella bronchiseptica Is Required for Efficient Establishment of Tracheal Colonization
Peggy A. Cotter, Ming H. Yuk, Seema Mattoo, Brian J. Akerley, Jeff Boschwitz, David A. Relman, Jeff F. Miller
MOLECULAR AND CELLULAR PATHOGENESIS
Actinobacillus actinomycetemcomitansToxin Induces Both Cell Cycle Arrest in the G₂/M Phase and Apoptosis
Masahiro Ohguchi, Akira Ishisaki, Nobuo Okahashi, Masanori Koide, Takeyoshi Koseki, Kenji Yamato, Toshihide Noguchi, Tatsuji Nishihara
MOLECULAR AND CELLULAR PATHOGENESIS
Internalization of Staphylococcus aureusby Endothelial Cells Induces Apoptosis
Barbara E. Menzies, Iordanka Kourteva
MOLECULAR AND CELLULAR PATHOGENESIS
Identification of the Helicobacter pylori VacA Toxin Domain Active in the Cell Cytosol
Marina de Bernard, Daniela Burroni, Emanuele Papini, Rino Rappuoli, John Telford, Cesare Montecucco
MOLECULAR AND CELLULAR PATHOGENESIS
Chlamydia trachomatis IncA Is Localized to the Inclusion Membrane and Is Recognized by Antisera from Infected Humans and Primates
John P. Bannantine, Walter E. Stamm, Robert J. Suchland, Daniel D. Rockey
MOLECULAR AND CELLULAR PATHOGENESIS
Structural Requirements for Glycosaminoglycan Recognition by the Lyme Disease Spirochete, Borrelia burgdorferi
John M. Leong, Douglas Robbins, Louis Rosenfeld, Biswajit Lahiri, Nikhat Parveen
MOLECULAR AND CELLULAR PATHOGENESIS
Enteropathogenic Escherichia coliVirulence Genes Encoding Secreted Signalling Proteins Are Essential for Modulation of Caco-2 Cell Electrolyte Transport
Georgina K. Collington, Ian W. Booth, Michael S. Donnenberg, James B. Kaper, Stuart Knutton

Microbial Immunity and Vaccines

Microbial Immunity and Vaccines
Genetic and Immunologic Analyses of PlpE, a Lipoprotein Important in Complement-Mediated Killing of Pasteurella haemolytica Serotype 1
Karamjeet Pandher, Anthony W. Confer, George L. Murphy
Microbial Immunity and Vaccines
Differences in Immune Responses Induced by Oral and Rectal Immunizations with Salmonella typhi Ty21a: Evidence for Compartmentalization within the Common Mucosal Immune System in Humans
A. Kantele, M. Häkkinen, Z. Moldoveanu, A. Lu, E. Savilahti, R. D. Alvarez, S. Michalek, J. Mestecky
Microbial Immunity and Vaccines
Systemic and Mucosal Immune Responses after Intranasal Administration of Recombinant Mycobacterium bovis Bacillus Calmette-Guérin Expressing Glutathione S-Transferase from Schistosoma haematobium
Laurent Kremer, Loïc Dupré, Gilles Riveau, André Capron, Camille Locht
Microbial Immunity and Vaccines
Mycobacterial Dose Defines the Th1/Th2 Nature of the Immune Response Independently of Whether Immunization Is Administered by the Intravenous, Subcutaneous, or Intradermal Route
Carl A. Power, Guojian Wei, Peter A. Bretscher
Microbial Immunity and Vaccines
Function and Protective Capacity of Treponema pallidum subsp. pallidum Glycerophosphodiester Phosphodiesterase
Caroline E. Cameron, Christa Castro, Sheila A. Lukehart, Wesley C. Van Voorhis
Microbial Immunity and Vaccines
Evaluation of Immunoglobulin A1 (IgA1) Protease and IgA1 Protease-Inhibitory Activity in Human Female Genital Infection with Neisseria gonorrhoeae
Spencer R. Hedges, Matthew S. Mayo, Lisa Kallman, Jiri Mestecky, Edward W. Hook, Michael W. Russell
Microbial Immunity and Vaccines
Intranasal Immunization with Cytotoxic T-Lymphocyte Epitope Peptide and Mucosal Adjuvant Cholera Toxin: Selective Augmentation of Peptide-Presenting Dendritic Cells in Nasal Mucosa-Associated Lymphoid Tissue
Angel Porgador, Herman F. Staats, Yasushi Itoh, Brian L. Kelsall
Microbial Immunity and Vaccines
Specific-Antibody-Secreting Cells in the Rectums and Genital Tracts of Nonhuman Primates following Vaccination
Kristina Eriksson, Marianne Quiding-Järbrink, Jacek Osek, Åke Möller, Stellan Björk, Jan Holmgren, Cecil Czerkinsky
Microbial Immunity and Vaccines
The (α2→8)-Linked Polysialic Acid Capsule and Lipooligosaccharide Structure Both Contribute to the Ability of Serogroup B Neisseria meningitidis To Resist the Bactericidal Activity of Normal Human Serum
C. M. Kahler, L. E. Martin, G. C. Shih, M. M. Rahman, R. W. Carlson, D. S. Stephens

Bacterial Infections

Bacterial Infections
Identification of Immunodominant Regions within the C-Terminal Cell Binding Domain of Intimin α and Intimin β from Enteropathogenic Escherichia coli
Jeannette Adu-Bobie, Luiz R. Trabulsi, Magda M. S. Carneiro-Sampaio, Gordon Dougan, Gad Frankel
Bacterial Infections
Role of NK Cells in Early Host Response to Chlamydial Genital Infection
Chien-Te Kent Tseng, Roger G. Rank
Bacterial Infections
Streptococcus sanguis-Induced Platelet Clotting in Rabbits and Hemodynamic and Cardiopulmonary Consequences
Maurice W. Meyer, Ke Gong, Mark C. Herzberg
Bacterial Infections
Phosphatidylcholine-Specific Phospholipase C from Listeria monocytogenes Is an Important Virulence Factor in Murine Cerebral Listeriosis
Dirk Schlüter, Eugen Domann, Christine Buck, Torsten Hain, Herbert Hof, Trinad Chakraborty, Martina Deckert-Schlüter
Bacterial Infections
Selective Activation of sar Promoters with the Use of Green Fluorescent Protein Transcriptional Fusions as the Detection System in the Rabbit Endocarditis Model
A. L. Cheung, Cynthia C. Nast, A. S. Bayer
Bacterial Infections
The Hemagglutination-Positive Phenotype of Mycoplasma synoviae Induces Experimental Infectious Synovitis in Chickens More Frequently than Does the Hemagglutination-Negative Phenotype
M. Narat, D. Bencina, S. H. Kleven, F. Habe
Bacterial Infections
Identification of a Chlamydia trachomatis Serovar E Urogenital Isolate Which Lacks the Cryptic Plasmid
Diane R. Stothard, James A. Williams, Barbara Van Der Pol, Robert B. Jones
Bacterial Infections
Persistence of Anaplasma ovis Infection and Conservation of the msp-2 and msp-3 Multigene Families within the Genus Anaplasma
Guy H. Palmer, Jeffrey R. Abbott, Dorothy M. French, Terry F. McElwain

Host Response and Inflammation

Host Response and Inflammation
Interleukin-15 May Be Responsible for Early Activation of Intestinal Intraepithelial Lymphocytes after Oral Infection with Listeria monocytogenes in Rats
Kenji Hirose, Hirohiko Suzuki, Hitoshi Nishimura, Akio Mitani, Junji Washizu, Tetsuya Matsuguchi, Yasunobu Yoshikai
Host Response and Inflammation
Cloning and Sequencing of yajC and secDHomologs of Brucella abortus and Demonstration of Immune Responses to YajC in Mice Vaccinated with B. abortus RB51
Ramesh Vemulapalli, A. Jane Duncan, Stephen M. Boyle, Nammalwar Sriranganathan, Thomas E. Toth, Gerhardt G. Schurig
Host Response and Inflammation
Pseudomonas Pyocyanin Increases Interleukin-8 Expression by Human Airway Epithelial Cells
Gerene M. Denning, Laura A. Wollenweber, Michelle A. Railsback, Charles D. Cox, Lynn L. Stoll, Bradley E. Britigan
Host Response and Inflammation
Relationship of Structure and Biological Activity of Monosaccharide Lipid A Analogues to Induction of Nitric Oxide Production by Murine Macrophage RAW264.7 Cells
Keiji Funatogawa, Motohiro Matsuura, Masayasu Nakano, Makoto Kiso, Akira Hasegawa
Host Response and Inflammation
Relationship between Hydroxy Fatty Acids and Prostaglandin E₂ in Gingival Tissue
Frank Nichols, Baliram Maraj
Host Response and Inflammation
Modulation of Lipopolysaccharide-Induced Monocyte Activation by Heparin-Binding Protein and Fucoidan
Michael Heinzelmann, Hiram C. Polk, Frederick N. Miller
Host Response and Inflammation
Estimation of Group B Streptococcus Type III Polysaccharide-Specific Antibody Concentrations in Human Sera Is Antigen Dependent
Reva Bhushan, Bascom F. Anthony, Carl E. Frasch
Host Response and Inflammation
Salmonella typhimurium Infection in Mice Induces Nitric Oxide-Mediated Immunosuppression through a Natural Killer Cell-Dependent Pathway
Martin G. Schwacha, Joseph J. Meissler, Toby K. Eisenstein
Host Response and Inflammation
Characterization of Human Immunoglobulin (Ig) Isotype and IgG Subclass Response to Bartonella henselae Infection
Svena L. McGill, Russell L. Regnery, Kevin L. Karem
Host Response and Inflammation
Detection of Anionic Antimicrobial Peptides in Ovine Bronchoalveolar Lavage Fluid and Respiratory Epithelium
Kim A. Brogden, Mark Ackermann, Kenneth M. Huttner
Host Response and Inflammation
Local Cytokine Response in Helicobacter pylori-Infected Subjects
C. Lindholm, M. Quiding-Järbrink, H. Lönroth, A. Hamlet, A.-M. Svennerholm
Host Response and Inflammation
Correlation of Cecal Microflora of HLA-B27 Transgenic Rats with Inflammatory Bowel Disease
Andrew B. Onderdonk, James A. Richardson, Robert E. Hammer, Joel D. Taurog
Host Response and Inflammation
Contrasting Roles of Mannan-Specific Monoclonal Immunoglobulin M Antibodies in the Activation of Classical and Alternative Pathways by Candida albicans
Mason X. Zhang, Jim E. Cutler, Yongmoon Han, Thomas R. Kozel
Host Response and Inflammation
Phagocytic and Tumor Necrosis Factor Alpha Response of Human Mast Cells following Exposure to Gram-Negative and Gram-Positive Bacteria
Michel Arock, Elaine Ross, René Lai-Kuen, Geneviève Averlant, Zhimin Gao, Soman N. Abraham
Host Response and Inflammation
Invasion of Human Oral Epithelial Cells byPrevotella intermedia
Brian R. Dorn, K.-P. Leung, Ann Progulske-Fox
Host Response and Inflammation
Lactobacilli and Streptococci Induce Interleukin-12 (IL-12), IL-18, and Gamma Interferon Production in Human Peripheral Blood Mononuclear Cells
Minja Miettinen, Sampsa Matikainen, Jaana Vuopio-Varkila, Jaana Pirhonen, Kari Varkila, Masashi Kurimoto, Ilkka Julkunen

Molecular Genomics

Molecular Genomics
Complete DNA Sequence and Detailed Analysis of the Yersinia pestis KIM5 Plasmid Encoding Murine Toxin and Capsular Antigen
Luther E. Lindler, Gregory V. Plano, Valerie Burland, George F. Mayhew, Frederick R. Blattner

Fungal and Parasitic Infections

Fungal and Parasitic Infections
A Vaccine and Monoclonal Antibodies That Enhance Mouse Resistance to Candida albicans Vaginal Infection
Yongmoon Han, Richard P. Morrison, Jim E. Cutler
Fungal and Parasitic Infections
Minimum Chemical Requirements for Adhesin Activity of the Acid-Stable Part of Candida albicans Cell Wall Phosphomannoprotein Complex
Toshio Kanbe, Jim E. Cutler
Fungal and Parasitic Infections
Filarial Nematode Parasites Secrete a Homologue of the Human Cytokine Macrophage Migration Inhibitory Factor
Diana V. Pastrana, Nithyakalyani Raghavan, Peter FitzGerald, Stephen W. Eisinger, Christine Metz, Richard Bucala, Robert P. Schleimer, Carol Bickel, Alan L. Scott
Fungal and Parasitic Infections
Evidence for Multiple Pathologic and Protective Mechanisms of Murine Cerebral Malaria
Veronica M. Jennings, Altaf A. Lal, Robert L. Hunter
Fungal and Parasitic Infections
Tumor Necrosis Factor Alpha Enhances Antifungal Activities of Polymorphonuclear and Mononuclear Phagocytes againstAspergillus fumigatus
Emmanuel Roilides, Anastasia Dimitriadou-Georgiadou, Tin Sein, Isaac Kadiltsoglou, Thomas J. Walsh
Fungal and Parasitic Infections
Sialic Acid-Dependent Recognition of Laminin byPenicillium marneffei Conidia
A. J. Hamilton, L. Jeavons, S. Youngchim, N. Vanittanakom, R. J. Hay
Fungal and Parasitic Infections
Reciprocal Regulation of Th1- and Th2-Cytokine-Producing T Cells during Clearance of Parasitemia in Plasmodium falciparum Malaria
Stefan Winkler, Martin Willheim, Karin Baier, Daniela Schmid, Alexander Aichelburg, Wolfgang Graninger, Peter G. Kremsner

Letters

Letters to the Editor
Reflux in the Mouse Model of Urinary Tract Infection
James R. Johnson