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Bacterial Infections

Genetic and Biochemical Analysis of Mutacin 1140, a Lantibiotic from Streptococcus mutans

J. D. Hillman, Jan Novák, Edy Sagura, Juan A. Gutierrez, T. A. Brooks, Paula J. Crowley, M. Hess, Abdul Azizi, K.-P. Leung, Dennis Cvitkovitch, A. S. Bleiweis
J. D. Hillman
Department of Oral Biology, University of Florida College of Dentistry, and
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Jan Novák
Departments of Microbiology and Oral Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294
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Edy Sagura
Interdisciplinary Center for Biological Research Protein Chemistry Core, University of Florida College of Medicine, Gainesville, Florida 32610, and
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Juan A. Gutierrez
Department of Oral Biology, University of Florida College of Dentistry, and
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T. A. Brooks
Department of Oral Biology, University of Florida College of Dentistry, and
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Paula J. Crowley
Department of Oral Biology, University of Florida College of Dentistry, and
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M. Hess
Department of Oral Biology, University of Florida College of Dentistry, and
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Abdul Azizi
Department of Oral Biology, University of Florida College of Dentistry, and
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K.-P. Leung
Department of Oral Biology, University of Florida College of Dentistry, and
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Dennis Cvitkovitch
Department of Oral Biology, University of Florida College of Dentistry, and
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A. S. Bleiweis
Department of Oral Biology, University of Florida College of Dentistry, and
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DOI: 10.1128/IAI.66.6.2743-2749.1998
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Article Information

DOI 
https://doi.org/10.1128/IAI.66.6.2743-2749.1998
PubMed 
9596742

Published By 
American Society for Microbiology Journals
History 
  • Received November 24, 1997
  • Returned for modification December 18, 1997
  • Accepted March 4, 1998
  • Published online June 1, 1998.

Copyright & Usage 
Copyright © 1998 American Society for Microbiology

Author Information

  1. J. D. Hillman1*,
  2. Jan Novák2,
  3. Edy Sagura3,
  4. Juan A. Gutierrez1†,
  5. T. A. Brooks1,
  6. Paula J. Crowley1,
  7. M. Hess1,
  8. Abdul Azizi1,
  9. K.-P. Leung1,
  10. Dennis Cvitkovitch1‡ and
  11. A. S. Bleiweis1
  1. Department of Oral Biology, University of Florida College of Dentistry,1 and
  2. Interdisciplinary Center for Biological Research Protein Chemistry Core, University of Florida College of Medicine,3 Gainesville, Florida 32610, and
  3. Departments of Microbiology and Oral Biology, University of Alabama at Birmingham, Birmingham, Alabama 352942
  • ↵* Corresponding author. Mailing address: University of Florida School of Dentistry, Box 100424, Gainesville, FL 32610. Phone: (352) 846-0792. Fax: (352) 392-2361. E-mail:jhillman{at}dental.ufl.edu.

  • ↵† Present address: Millennium Pharmaceuticals, Inc., Cambridge, MA 02189.; ‡ Present address: University of Toronto Dental Research Institute, Toronto, Canada M5G 1G6.

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Genetic and Biochemical Analysis of Mutacin 1140, a Lantibiotic from Streptococcus mutans
J. D. Hillman, Jan Novák, Edy Sagura, Juan A. Gutierrez, T. A. Brooks, Paula J. Crowley, M. Hess, Abdul Azizi, K.-P. Leung, Dennis Cvitkovitch, A. S. Bleiweis
Infection and Immunity Jun 1998, 66 (6) 2743-2749; DOI: 10.1128/IAI.66.6.2743-2749.1998

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Genetic and Biochemical Analysis of Mutacin 1140, a Lantibiotic from Streptococcus mutans
J. D. Hillman, Jan Novák, Edy Sagura, Juan A. Gutierrez, T. A. Brooks, Paula J. Crowley, M. Hess, Abdul Azizi, K.-P. Leung, Dennis Cvitkovitch, A. S. Bleiweis
Infection and Immunity Jun 1998, 66 (6) 2743-2749; DOI: 10.1128/IAI.66.6.2743-2749.1998
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KEYWORDS

Anti-Bacterial Agents
Bacteriocins
Peptides
Streptococcus mutans

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