Skip to main content
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems
  • Log in
  • My alerts
  • My Cart

Main menu

  • Home
  • Articles
    • Current Issue
    • Accepted Manuscripts
    • Archive
    • Minireviews
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About IAI
    • Editor in Chief
    • Editorial Board
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ
  • Subscribe
    • Members
    • Institutions
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems

User menu

  • Log in
  • My alerts
  • My Cart

Search

  • Advanced search
Infection and Immunity
publisher-logosite-logo

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Accepted Manuscripts
    • Archive
    • Minireviews
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About IAI
    • Editor in Chief
    • Editorial Board
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ
  • Subscribe
    • Members
    • Institutions
Bacterial Infections

Klebsiella pneumoniae Capsule Expression Is Necessary for Colonization of Large Intestines of Streptomycin-Treated Mice

Sabine Favre-Bonté, Tine Rask Licht, Christiane Forestier, Karen Angeliki Krogfelt
Sabine Favre-Bonté
Department of Gastrointestinal Infections, Statens Serum Institut, Copenhagen, and
Laboratoire de Bactériologie, Faculté de Pharmacie, Universitéd'Auvergne, Clermont-Ferrand, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tine Rask Licht
Department of Gastrointestinal Infections, Statens Serum Institut, Copenhagen, and
Department of Microbiology, Technical University of Denmark, Lyngby, Denmark, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christiane Forestier
Laboratoire de Bactériologie, Faculté de Pharmacie, Universitéd'Auvergne, Clermont-Ferrand, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Karen Angeliki Krogfelt
Department of Gastrointestinal Infections, Statens Serum Institut, Copenhagen, and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
DOI: 10.1128/IAI.67.11.6152-6156.1999
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Article Figures & Data

Figures

  • Fig. 1.
    • Open in new tab
    • Download powerpoint
    Fig. 1.

    Colonization by wild-type K. pneumoniae LM21 (■) and its capsule-defective mutant, K. pneumoniaeLM21(cps) (▴), of the intestines of streptomycin-treated mice. The strains were fed separately to each of three streptomycin-treated mice. Symbols for day 0 represent the sizes of the inocula. At the indicated times, fecal samples were plated as described in the text. The detection limit is marked by a broken line. Bars represent standard errors of the means.

  • Fig. 2.
    • Open in new tab
    • Download powerpoint
    Fig. 2.

    Co-colonization by wild-type K. pneumoniaeLM21 (■) and its capsule-defective mutant, K. pneumoniaeLM21(cps) (▴), of the intestines of streptomycin-treated mice. (A) The strains were fed simultaneously at 108 CFU to streptomycin-treated mice. (B) The strains were fed simultaneously at 105 CFU to streptomycin-treated mice. Symbols for day 0 represent the sizes of the inocula. At the indicated times, fecal samples were plated as described in the text. Bars represent standard errors of the means.

  • Fig. 3.
    • Open in new tab
    • Download powerpoint
    Fig. 3.

    Colonic sections of mice fed wild-type K. pneumoniae LM21 (A) and the K. pneumoniae LM21(cps) capsule-defective mutant (B) on day 1 after onset of infection. (Left) Phase-contrast picture of the corresponding area of in situ hybridization. (Right) In situ hybridization with fluorescence-labeled oligonucleotide probes. K. pneumoniae bacteria appear red, while other eubacteria appear green. The colonic epithelium (Ep) is fluorescent because of the autofluorescence of the eucaryotic tissue. Bars, 10 μm.

  • Fig. 4.
    • Open in new tab
    • Download powerpoint
    Fig. 4.

    Colonic sections of mice fed wild-type K. pneumoniae LM21 (A) and the K. pneumoniae LM21(cps) capsule-defective mutant (B) on day 20 after infection. (Left) Phase-contrast picture of the corresponding area of in situ hybridization. (Right) In situ hybridization with fluorescence-labeled oligonucleotide probes. K. pneumoniae bacteria appear red, while other eubacteria appear green. The colonic epithelium (Ep) is fluorescent because of the autofluorescence of the eucaryotic tissue. Bars, 10 μm.

PreviousNext
Back to top
Download PDF
Citation Tools
Klebsiella pneumoniae Capsule Expression Is Necessary for Colonization of Large Intestines of Streptomycin-Treated Mice
Sabine Favre-Bonté, Tine Rask Licht, Christiane Forestier, Karen Angeliki Krogfelt
Infection and Immunity Nov 1999, 67 (11) 6152-6156; DOI: 10.1128/IAI.67.11.6152-6156.1999

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Print

Alerts
Sign In to Email Alerts with your Email Address
Email

Thank you for sharing this Infection and Immunity article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Klebsiella pneumoniae Capsule Expression Is Necessary for Colonization of Large Intestines of Streptomycin-Treated Mice
(Your Name) has forwarded a page to you from Infection and Immunity
(Your Name) thought you would be interested in this article in Infection and Immunity.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Klebsiella pneumoniae Capsule Expression Is Necessary for Colonization of Large Intestines of Streptomycin-Treated Mice
Sabine Favre-Bonté, Tine Rask Licht, Christiane Forestier, Karen Angeliki Krogfelt
Infection and Immunity Nov 1999, 67 (11) 6152-6156; DOI: 10.1128/IAI.67.11.6152-6156.1999
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Top
  • Article
    • ABSTRACT
    • ACKNOWLEDGMENTS
    • Notes
    • FOOTNOTES
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • PDF

KEYWORDS

Anti-Bacterial Agents
Bacterial Capsules
colon
Klebsiella pneumoniae
Streptomycin

Related Articles

Cited By...

About

  • About IAI
  • Editor in Chief
  • Editorial Board
  • Policies
  • For Reviewers
  • For the Media
  • For Librarians
  • For Advertisers
  • Alerts
  • RSS
  • FAQ
  • Permissions
  • Journal Announcements

Authors

  • ASM Author Center
  • Submit a Manuscript
  • Article Types
  • Ethics
  • Contact Us

Follow #IAIjournal

@ASMicrobiology

       

ASM Journals

ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology.

About ASM | Contact Us | Press Room

 

ASM is a member of

Scientific Society Publisher Alliance

 

American Society for Microbiology
1752 N St. NW
Washington, DC 20036
Phone: (202) 737-3600

Copyright © 2021 American Society for Microbiology | Privacy Policy | Website feedback

Print ISSN: 0019-9567; Online ISSN: 1098-5522