Article Figures & Data
Figures
- Fig. 1.
Colonization by wild-type K. pneumoniae LM21 (■) and its capsule-defective mutant, K. pneumoniaeLM21(cps) (▴), of the intestines of streptomycin-treated mice. The strains were fed separately to each of three streptomycin-treated mice. Symbols for day 0 represent the sizes of the inocula. At the indicated times, fecal samples were plated as described in the text. The detection limit is marked by a broken line. Bars represent standard errors of the means.
- Fig. 2.
Co-colonization by wild-type K. pneumoniaeLM21 (■) and its capsule-defective mutant, K. pneumoniaeLM21(cps) (▴), of the intestines of streptomycin-treated mice. (A) The strains were fed simultaneously at 108 CFU to streptomycin-treated mice. (B) The strains were fed simultaneously at 105 CFU to streptomycin-treated mice. Symbols for day 0 represent the sizes of the inocula. At the indicated times, fecal samples were plated as described in the text. Bars represent standard errors of the means.
- Fig. 3.
Colonic sections of mice fed wild-type K. pneumoniae LM21 (A) and the K. pneumoniae LM21(cps) capsule-defective mutant (B) on day 1 after onset of infection. (Left) Phase-contrast picture of the corresponding area of in situ hybridization. (Right) In situ hybridization with fluorescence-labeled oligonucleotide probes. K. pneumoniae bacteria appear red, while other eubacteria appear green. The colonic epithelium (Ep) is fluorescent because of the autofluorescence of the eucaryotic tissue. Bars, 10 μm.
- Fig. 4.
Colonic sections of mice fed wild-type K. pneumoniae LM21 (A) and the K. pneumoniae LM21(cps) capsule-defective mutant (B) on day 20 after infection. (Left) Phase-contrast picture of the corresponding area of in situ hybridization. (Right) In situ hybridization with fluorescence-labeled oligonucleotide probes. K. pneumoniae bacteria appear red, while other eubacteria appear green. The colonic epithelium (Ep) is fluorescent because of the autofluorescence of the eucaryotic tissue. Bars, 10 μm.
