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Microbial Immunity and Vaccines

Variability of Outer Membrane Protein P1 and Its Evaluation as a Vaccine Candidate against Experimental Otitis Media due to Nontypeable Haemophilus influenzae: an Unambiguous, Multifaceted Approach

Gilles R. Bolduc, Valérie Bouchet, Ru-Zhang Jiang, Janet Geisselsoder, Que Chi Truong-Bolduc, Peter A. Rice, Stephen I. Pelton, Richard Goldstein
Gilles R. Bolduc
The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
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Valérie Bouchet
The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
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Ru-Zhang Jiang
The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
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Janet Geisselsoder
The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
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Que Chi Truong-Bolduc
The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
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Peter A. Rice
The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
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Stephen I. Pelton
The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
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Richard Goldstein
The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
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DOI: 10.1128/IAI.68.8.4505-4517.2000
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Article Information

DOI 
https://doi.org/10.1128/IAI.68.8.4505-4517.2000
PubMed 
10899849

Published By 
American Society for Microbiology Journals
History 
  • Received February 11, 2000
  • Returned for modification March 23, 2000
  • Accepted May 5, 2000
  • Published online August 1, 2000.

Copyright & Usage 
Copyright © 2000 American Society for Microbiology

Author Information

  1. Gilles R. Bolduc†,
  2. Valérie Bouchet,
  3. Ru-Zhang Jiang‡,
  4. Janet Geisselsoder,
  5. Que Chi Truong-Bolduc,
  6. Peter A. Rice,
  7. Stephen I. Pelton and
  8. Richard Goldstein*
  1. The Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118
  • ↵* Corresponding author. Mailing address: Section of Molecular Genetics, Division of Pediatric Infectious Diseases, Maxwell Finland Laboratory for Infectious Diseases, Boston University School of Medicine, 774 Albany St., Boston, MA 02118. Phone: (617) 638-5328. Fax: (617) 414-7222. E-mail: genetics{at}bu.edu.

  • ↵† Present address: Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.; ‡ Present address: Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071, People's Republic of China.

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Variability of Outer Membrane Protein P1 and Its Evaluation as a Vaccine Candidate against Experimental Otitis Media due to Nontypeable Haemophilus influenzae: an Unambiguous, Multifaceted Approach
Gilles R. Bolduc, Valérie Bouchet, Ru-Zhang Jiang, Janet Geisselsoder, Que Chi Truong-Bolduc, Peter A. Rice, Stephen I. Pelton, Richard Goldstein
Infection and Immunity Aug 2000, 68 (8) 4505-4517; DOI: 10.1128/IAI.68.8.4505-4517.2000

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Variability of Outer Membrane Protein P1 and Its Evaluation as a Vaccine Candidate against Experimental Otitis Media due to Nontypeable Haemophilus influenzae: an Unambiguous, Multifaceted Approach
Gilles R. Bolduc, Valérie Bouchet, Ru-Zhang Jiang, Janet Geisselsoder, Que Chi Truong-Bolduc, Peter A. Rice, Stephen I. Pelton, Richard Goldstein
Infection and Immunity Aug 2000, 68 (8) 4505-4517; DOI: 10.1128/IAI.68.8.4505-4517.2000
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KEYWORDS

antigenic variation
Bacterial Outer Membrane Proteins
Haemophilus Vaccines
Haemophilus influenzae
otitis media

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