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Molecular Pathogenesis

Synergistic Effects of Alpha-Toxin and Perfringolysin O in Clostridium perfringens-Mediated Gas Gangrene

Milena M. Awad, Darren M. Ellemor, Richard L. Boyd, John J. Emmins, Julian I. Rood
Milena M. Awad
Bacterial Pathogenesis Research Group, Department of Microbiology, Monash University, Victoria 3800, and
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Darren M. Ellemor
Department of Pathology and Immunology, Monash University Medical School, Alfred Hospital, Prahran 3181, Australia
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Richard L. Boyd
Department of Pathology and Immunology, Monash University Medical School, Alfred Hospital, Prahran 3181, Australia
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John J. Emmins
Department of Pathology and Immunology, Monash University Medical School, Alfred Hospital, Prahran 3181, Australia
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Julian I. Rood
Bacterial Pathogenesis Research Group, Department of Microbiology, Monash University, Victoria 3800, and
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DOI: 10.1128/IAI.69.12.7904-7910.2001
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Article Information

DOI 
https://doi.org/10.1128/IAI.69.12.7904-7910.2001
PubMed 
11705975

Published By 
American Society for Microbiology Journals
History 
  • Received June 8, 2001
  • Returned for modification July 24, 2001
  • Accepted August 24, 2001
  • Published online December 1, 2001.

Copyright & Usage 
Copyright © 2001 American Society for Microbiology

Author Information

  1. Milena M. Awad1,
  2. Darren M. Ellemor2,
  3. Richard L. Boyd2,
  4. John J. Emmins2 and
  5. Julian I. Rood1*
  1. Bacterial Pathogenesis Research Group, Department of Microbiology, Monash University, Victoria 3800,1 and
  2. Department of Pathology and Immunology, Monash University Medical School, Alfred Hospital, Prahran 3181,2 Australia
  • ↵* Corresponding author. Mailing address: Bacterial Pathogenesis Research Group, Department of Microbiology, Monash University, P.O. Box 53, Victoria 3800, Australia. Phone: (613) 99054825. Fax: (613) 99054811. E-mail:Julian.Rood{at}med.monash.edu.au.

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Synergistic Effects of Alpha-Toxin and Perfringolysin O in Clostridium perfringens-Mediated Gas Gangrene
Milena M. Awad, Darren M. Ellemor, Richard L. Boyd, John J. Emmins, Julian I. Rood
Infection and Immunity Dec 2001, 69 (12) 7904-7910; DOI: 10.1128/IAI.69.12.7904-7910.2001

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Synergistic Effects of Alpha-Toxin and Perfringolysin O in Clostridium perfringens-Mediated Gas Gangrene
Milena M. Awad, Darren M. Ellemor, Richard L. Boyd, John J. Emmins, Julian I. Rood
Infection and Immunity Dec 2001, 69 (12) 7904-7910; DOI: 10.1128/IAI.69.12.7904-7910.2001
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KEYWORDS

bacterial toxins
Calcium-Binding Proteins
Clostridium perfringens
gas gangrene
Type C Phospholipases

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