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Molecular Pathogenesis

The ClpP Protease of Streptococcus pneumoniae Modulates Virulence Gene Expression and Protects against Fatal Pneumococcal Challenge

Hyog-Young Kwon, A. David Ogunniyi, Moo-Hyun Choi, Suhk-Neung Pyo, Dong-Kwon Rhee, James C. Paton
Hyog-Young Kwon
1College of Pharmacy, Sungkyunkwan University, Suwon, Korea
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A. David Ogunniyi
2School of Molecular and Biomedical Science, University of Adelaide, Adelaide, South Australia, Australia
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Moo-Hyun Choi
1College of Pharmacy, Sungkyunkwan University, Suwon, Korea
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Suhk-Neung Pyo
1College of Pharmacy, Sungkyunkwan University, Suwon, Korea
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Dong-Kwon Rhee
1College of Pharmacy, Sungkyunkwan University, Suwon, Korea
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  • For correspondence: dkrhee@skku.edu
James C. Paton
2School of Molecular and Biomedical Science, University of Adelaide, Adelaide, South Australia, Australia
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DOI: 10.1128/IAI.72.10.5646-5653.2004
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Article Information

DOI 
https://doi.org/10.1128/IAI.72.10.5646-5653.2004
PubMed 
15385462

Published By 
American Society for Microbiology Journals
History 
  • Received December 23, 2003
  • Returned for modification May 6, 2004
  • Accepted July 7, 2004
  • Published online September 22, 2004.

Copyright & Usage 
Copyright © 2004 American Society for Microbiology

Author Information

  1. Hyog-Young Kwon1†,
  2. A. David Ogunniyi2†,
  3. Moo-Hyun Choi1,
  4. Suhk-Neung Pyo1,
  5. Dong-Kwon Rhee1* and
  6. James C. Paton2
  1. 1College of Pharmacy, Sungkyunkwan University, Suwon, Korea
  2. 2School of Molecular and Biomedical Science, University of Adelaide, Adelaide, South Australia, Australia
  • ↵† H.-Y.K. and A.D.O. contributed equally to this work.

  • ↵* Corresponding author. Mailing address: College of Pharmacy, Sungkyunkwan University, Suwon 440-746, South Korea. Phone: 82 31 2907707. Fax: 82 31 2928800. E-mail: dkrhee{at}skku.edu .
  • Editor: V. J. DiRita

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The ClpP Protease of Streptococcus pneumoniae Modulates Virulence Gene Expression and Protects against Fatal Pneumococcal Challenge
Hyog-Young Kwon, A. David Ogunniyi, Moo-Hyun Choi, Suhk-Neung Pyo, Dong-Kwon Rhee, James C. Paton
Infection and Immunity Sep 2004, 72 (10) 5646-5653; DOI: 10.1128/IAI.72.10.5646-5653.2004

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The ClpP Protease of Streptococcus pneumoniae Modulates Virulence Gene Expression and Protects against Fatal Pneumococcal Challenge
Hyog-Young Kwon, A. David Ogunniyi, Moo-Hyun Choi, Suhk-Neung Pyo, Dong-Kwon Rhee, James C. Paton
Infection and Immunity Sep 2004, 72 (10) 5646-5653; DOI: 10.1128/IAI.72.10.5646-5653.2004
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KEYWORDS

Adenosine Triphosphatases
Gene Expression Regulation, Bacterial
Pneumococcal Infections
Serine Endopeptidases
Streptococcus pneumoniae

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