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Microbial Immunity and Vaccines

Demonstration of OspC Type Diversity in Invasive Human Lyme Disease Isolates and Identification of Previously Uncharacterized Epitopes That Define the Specificity of the OspC Murine Antibody Response

Christopher G. Earnhart, Eric L. Buckles, John Stephen Dumler, Richard T. Marconi
Christopher G. Earnhart
1Department of Microbiology and Immunology
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Eric L. Buckles
1Department of Microbiology and Immunology
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John Stephen Dumler
2Johns Hopkins University, Baltimore, Maryland
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Richard T. Marconi
1Department of Microbiology and Immunology
3Center for the Study of Biological Complexity, Medical College of Virginia at Virginia Commonwealth University, Richmond, Virginia 23298-0678
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  • For correspondence: rmarconi@hsc.vcu.edu
DOI: 10.1128/IAI.73.12.7869-7877.2005
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Article Information

DOI 
https://doi.org/10.1128/IAI.73.12.7869-7877.2005
PubMed 
16299277

Published By 
American Society for Microbiology Journals
History 
  • Received March 15, 2005
  • Returned for modification July 26, 2005
  • Accepted August 28, 2005
  • Published online November 18, 2005.

Copyright & Usage 
Copyright © 2005 American Society for Microbiology

Author Information

  1. Christopher G. Earnhart1,
  2. Eric L. Buckles1,
  3. John Stephen Dumler2 and
  4. Richard T. Marconi1,3*
  1. 1Department of Microbiology and Immunology
  2. 3Center for the Study of Biological Complexity, Medical College of Virginia at Virginia Commonwealth University, Richmond, Virginia 23298-0678
  3. 2Johns Hopkins University, Baltimore, Maryland
  • ↵* Corresponding author. Mailing address: Department of Microbiology and Immunology, Medical College of Virginia at Virginia Commonwealth University, Richmond, VA 23298-0678. Phone: (804) 828-3779. Fax: (804) 828-9946. E-mail: rmarconi{at}hsc.vcu.edu .
  • Editor: V. J. DiRita

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Demonstration of OspC Type Diversity in Invasive Human Lyme Disease Isolates and Identification of Previously Uncharacterized Epitopes That Define the Specificity of the OspC Murine Antibody Response
Christopher G. Earnhart, Eric L. Buckles, John Stephen Dumler, Richard T. Marconi
Infection and Immunity Nov 2005, 73 (12) 7869-7877; DOI: 10.1128/IAI.73.12.7869-7877.2005

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Demonstration of OspC Type Diversity in Invasive Human Lyme Disease Isolates and Identification of Previously Uncharacterized Epitopes That Define the Specificity of the OspC Murine Antibody Response
Christopher G. Earnhart, Eric L. Buckles, John Stephen Dumler, Richard T. Marconi
Infection and Immunity Nov 2005, 73 (12) 7869-7877; DOI: 10.1128/IAI.73.12.7869-7877.2005
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KEYWORDS

Antibodies, Bacterial
Antibody Specificity
Antigens, Bacterial
Bacterial Outer Membrane Proteins
Borrelia burgdorferi
epitopes
Lyme disease

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