Infection and Immunity: 73 (9)

September 2005; Volume 73,Issue 9

Molecular Pathogenesis

Molecular Pathogenesis
Novel Sialic Acid Transporter of Haemophilus influenzae
Simon Allen, Anthony Zaleski, Jason W. Johnston, Bradford W. Gibson, Michael A. Apicella
Molecular Pathogenesis
Cytotoxic Necrotizing Factor Type 1 Production by Uropathogenic Escherichia coli Modulates Polymorphonuclear Leukocyte Function
Jon M. Davis, Susan B. Rasmussen, Alison D. O'Brien
Molecular Pathogenesis
Helicobacter hepaticus Hydrogenase Mutants Are Deficient in Hydrogen-Supported Amino Acid Uptake and in Causing Liver Lesions in A/J Mice
Nalini S. Mehta, Stephane Benoit, Jagannatha V. Mysore, Renato S. Sousa, Robert J. Maier
Molecular Pathogenesis
Down Regulation of Virulence Factors of Pseudomonas aeruginosa by Salicylic Acid Attenuates Its Virulence on Arabidopsis thaliana and Caenorhabditis elegans
B. Prithiviraj, H. P. Bais, T. Weir, B. Suresh, E. H. Najarro, B. V. Dayakar, H. P. Schweizer, J. M. Vivanco
Molecular Pathogenesis
Salmonella enterica Serotype Typhimurium Fimbrial Proteins Serve as Antigens during Infection of Mice
Andrea Humphries, Sandra DeRidder, Andreas J. Bäumler
Molecular Pathogenesis
Incomplete Activation of Macrophage Apoptosis during Intracellular Replication of Legionella pneumophila
Alaeddin Abu-Zant, Marina Santic, Maelle Molmeret, Snake Jones, Jürgen Helbig, Yousef Abu Kwaik
Molecular Pathogenesis
Microarray-Based Detection of Salmonella enterica Serovar Typhimurium Transposon Mutants That Cannot Survive in Macrophages and Mice
Kaman Chan, Charles C. Kim, Stanley Falkow
Molecular Pathogenesis
Sequence Variation within Botulinum Neurotoxin Serotypes Impacts Antibody Binding and Neutralization
T. J. Smith, J. Lou, I. N. Geren, C. M. Forsyth, R. Tsai, S. L. LaPorte, W. H. Tepp, M. Bradshaw, E. A. Johnson, L. A. Smith, J. D. Marks
Molecular Pathogenesis
Mannheimia haemolytica Leukotoxin Induces Apoptosis of Bovine Lymphoblastoid Cells (BL-3) via a Caspase-9-Dependent Mitochondrial Pathway
Dhammika N. Atapattu, Charles J. Czuprynski
Molecular Pathogenesis
Identification of a New Virulence Factor, BvfA, in Brucella suis
Jean-Philippe Lavigne, Gilles Patey, Felix J. Sangari, Gisèle Bourg, Michel Ramuz, David O'Callaghan, Sylvie Michaux-Charachon
Molecular Pathogenesis
Role of FliF and FliI of Listeria monocytogenes in Flagellar Assembly and Pathogenicity
Armelle Bigot, Hélène Pagniez, Eléonore Botton, Claude Fréhel, Iharilalao Dubail, Christine Jacquet, Alain Charbit, Catherine Raynaud
Molecular Pathogenesis
Characterization of Novel Staphylococcal Enterotoxin-Like Toxin Type P
Katsuhiko Omoe, Ken'ichi Imanishi, Dong-Liang Hu, Hidehito Kato, Yoshitaku Fugane, Yohei Abe, Shoji Hamaoka, Yutaka Watanabe, Akio Nakane, Takehiko Uchiyama, Kunihiro Shinagawa
Molecular Pathogenesis
Borrelia burgdorferi Organisms Lacking Plasmids 25 and 28-1 Are Internalized by Human Blood Phagocytes at a Rate Identical to That of the Wild-Type Strain
Samiya Al-Robaiy, Jens Knauer, Reinhard K. Straubinger
Molecular Pathogenesis
Unusual Genetic Organization of a Functional Type I Protein Secretion System in Neisseria meningitidis
Karl G. Wooldridge, Murat Kizil, Damien B. Wells, Dlawer A. A. Ala'Aldeen
Molecular Pathogenesis
Rate of Inversion of the Salmonella enterica Shufflon Regulates Expression of Invertible DNA
Connie K. P. Tam, Jim Hackett, Christina Morris
Molecular Pathogenesis
Systematic Targeted Mutagenesis of Brucella melitensis 16M Reveals a Major Role for GntR Regulators in the Control ofVirulence
Valérie Haine, Audrey Sinon, Frédéric Van Steen, Stéphanie Rousseau, Marie Dozot, Pascal Lestrate, Christophe Lambert, Jean-Jacques Letesson, Xavier De Bolle
Molecular Pathogenesis
Mutations Affecting Peptidoglycan Acetylation in Neisseria gonorrhoeae and Neisseria meningitidis
Joseph P. Dillard, Kathleen T. Hackett
Molecular Pathogenesis
Characterization of Vibrio cholerae RyhB: the RyhB Regulon and Role of ryhB in Biofilm Formation
Alexandra R. Mey, Stephanie A. Craig, Shelley M. Payne
Molecular Pathogenesis
Components of the Legionella pneumophila Flagellar Regulon Contribute to Multiple Virulence Traits, Including Lysosome Avoidance and Macrophage Death
A. B. Molofsky, L. M. Shetron-Rama, Michele S. Swanson
Molecular Pathogenesis
Interaction of Bartonella henselae with Endothelial Cells Promotes Monocyte/Macrophage Chemoattractant Protein 1 Gene Expression and Protein Production and Triggers Monocyte Migration
Amy M. McCord, Andrew W. O. Burgess, Melissa J. Whaley, Burt E. Anderson
Molecular Pathogenesis
Characterization of MtsR, a New Metal Regulator in Group A Streptococcus, Involved in Iron Acquisition and Virulence
Christopher S. Bates, Chadia Toukoki, Melody N. Neely, Zehava Eichenbaum
Molecular Pathogenesis
vpaH, a Gene Encoding a Novel Histone-Like Nucleoid Structure-Like Protein That Was Possibly Horizontally Acquired, Regulates the Biogenesis of Lateral Flagella in trh-Positive Vibrio parahaemolyticus TH3996
Kwon-Sam Park, Michiko Arita, Tetsuya Iida, Takeshi Honda
Molecular Pathogenesis
Characterization of Genetic and Phenotypic Diversity of Invasive Nontypeable Haemophilus influenzae
Alice L. Erwin, Kevin L. Nelson, Tendai Mhlanga-Mutangadura, Paul J. Bonthuis, Jennifer L. Geelhood, Gregory Morlin, William C. T. Unrath, Jose Campos, Derrick W. Crook, Monica M. Farley, Frederick W. Henderson, Richard F. Jacobs, Kathrin Mühlemann, Sarah W. Satola, Loek van Alphen, Miriam Golomb, Arnold L. Smith
Molecular Pathogenesis
Novel Role of the Lipopolysaccharide O1 Side Chain in Ferric Siderophore Transport and Virulence of Vibrio anguillarum
Timothy J. Welch, Jorge H. Crosa
Molecular Pathogenesis
Cyclic Diguanylate Regulates Vibrio cholerae Virulence Gene Expression
Anna D. Tischler, Andrew Camilli
Molecular Pathogenesis
Environmental Regulation and Virulence Attributes of the Ysa Type III Secretion System of Yersinia enterocolitica Biovar 1B
Krista Venecia, Glenn M. Young
Molecular Pathogenesis
Both Corynebacterium diphtheriae DtxR(E175K) and Mycobacterium tuberculosis IdeR(D177K) Are Dominant Positive Repressors of IdeR-Regulated Genes in M. tuberculosis
Yukari C. Manabe, Christine L. Hatem, Anup K. Kesavan, Justin Durack, John R. Murphy
Molecular Pathogenesis
Bordetella pertussis risA, but Not risS, Is Required for Maximal Expression of Bvg-Repressed Genes
Trevor H. Stenson, Andrew G. Allen, Jehan A. al-Meer, Duncan Maskell, Mark S. Peppler
Molecular Pathogenesis
Brucella abortus VirB12 Is Expressed during Infection but Is Not an Essential Component of the Type IV Secretion System
Yao-Hui Sun, Hortensia G. Rolán, Andreas B. den Hartigh, David Sondervan, Renée M. Tsolis
Molecular Pathogenesis
Identification of Virulence Determinants for Endocarditis in Streptococcus sanguinis by Signature-Tagged Mutagenesis
Sehmi Paik, Lauren Senty, Sankar Das, Jody C. Noe, Cindy L. Munro, Todd Kitten
Molecular Pathogenesis
Characterization of the dapA-nlpB Genetic Locus Involved in Regulation of Swarming Motility, Cell Envelope Architecture, Hemolysin Production, and Cell Attachment Ability in Serratia marcescens
Po-Chi Soo, Jun-Rong Wei, Yu-Tze Horng, Shang-Chen Hsieh, Shen-Wu Ho, Hsin-Chih Lai
Molecular Pathogenesis
Complement Receptor 3 Binds the Borrelia burgdorferi Outer Surface Proteins OspA and OspB in an iC3b-Independent Manner
Rodolfo C. Garcia, Rossella Murgia, Marina Cinco
Molecular Pathogenesis
Gene Expression Profile Analysis of Porphyromonas gingivalis during Invasion of Human Coronary Artery Endothelial Cells
Paulo H. Rodrigues, Ann Progulske-Fox
Molecular Pathogenesis
Characterization of FimH Adhesins Expressed by Salmonella enterica Serovar Gallinarum Biovars Gallinarum and Pullorum: Reconstitution of Mannose-Binding Properties by Single Amino Acid Substitution
Dagmara Kisiela, Anna Sapeta, Maciej Kuczkowski, Tadeusz Stefaniak, Alina Wieliczko, Maciej Ugorski
Molecular Pathogenesis
Viability of a Capsule- and Lipopolysaccharide-Deficient Mutant of Neisseria meningitidis
Martine P. Bos, Jan Tommassen

Host Response and Inflammation

Host Response and Inflammation
Involvement of Fractalkine/CX3CL1 Expression by Dendritic Cells in the Enhancement of Host Immunity against Legionella pneumophila
Toshiaki Kikuchi, Sita Andarini, Hong Xin, Kazunori Gomi, Yutaka Tokue, Yasuo Saijo, Tasuku Honjo, Akira Watanabe, Toshihiro Nukiwa
Host Response and Inflammation
Persistence of Zinc-Binding Bacterial Superantigens at the Surface of Antigen-Presenting Cells Contributes to the Extreme Potency of These Superantigens as T-Cell Activators
Dorothy D. Pless, Gordon Ruthel, Emily K. Reinke, Robert G. Ulrich, Sina Bavari
Host Response and Inflammation
Porphyromonas gingivalis Fimbria-Dependent Activation of Inflammatory Genes in Human Aortic Endothelial Cells
Hsin-Hua Chou, Hiromichi Yumoto, Michael Davey, Yusuke Takahashi, Takanari Miyamoto, Frank C. Gibson, Caroline A. Genco
Host Response and Inflammation
Concurrent Infection with an Intestinal Helminth Parasite Impairs Host Resistance to Enteric Citrobacter rodentium and Enhances Citrobacter-Induced Colitis in Mice
Chien-Chang Chen, Steve Louie, Beth McCormick, W. Allan Walker, Hai Ning Shi
Host Response and Inflammation
Host Immune Status Influences the Development of Attaching and Effacing Lesions in Weaned Pigs
Francis Girard, Isabelle P. Oswald, Ionélia Taranu, Pierre Hélie, Greg D. Appleyard, Josée Harel, John M. Fairbrother
Host Response and Inflammation
Helicobacter pylori-Specific CD4⁺ T Cells Home to and Accumulate in the Human Helicobacter pylori-Infected Gastric Mucosa
Anna Lundgren, Christina Trollmo, Anders Edebo, Ann-Mari Svennerholm, B. Samuel Lundin
Host Response and Inflammation
Bacteroides fragilis-Derived Lipopolysaccharide Produces Cell Activation and Lethal Toxicity via Toll-Like Receptor 4
Giuseppe Mancuso, Angelina Midiri, Carmelo Biondo, Concetta Beninati, Maria Gambuzza, Daniele Macrì, Antonella Bellantoni, Andrej Weintraub, Terje Espevik, Giuseppe Teti
Host Response and Inflammation
Bovine NK Cells Can Produce Gamma Interferon in Response to the Secreted Mycobacterial Proteins ESAT-6 and MPP14 but Not in Response to MPB70
Ingrid Olsen, Preben Boysen, Siri Kulberg, Jayne C. Hope, Gregers Jungersen, Anne K. Storset
Host Response and Inflammation
Postgenomic Approach To Identify Novel Mycobacterium leprae Antigens with Potential To Improve Immunodiagnosis of Infection
Annemieke Geluk, Michèl R. Klein, Kees L. M. C. Franken, Krista E. van Meijgaarden, Brigitte Wieles, Kelly Cristina Pereira, Samira Bührer-Sékula, Paul R. Klatser, Patrick J. Brennan, John S. Spencer, Diana L. Williams, Maria C. V. Pessolani, Elizabeth P. Sampaio, Tom H. M. Ottenhoff
Host Response and Inflammation
Characterization of Salivary Immunoglobulin A Responses in Children Heavily Exposed to the Oral Bacterium Streptococcus mutans: Influence of Specific Antigen Recognition in Infection
Ruchele D. Nogueira, Alessandra C. Alves, Marcelo H. Napimoga, Daniel J. Smith, Renata O. Mattos-Graner
Host Response and Inflammation
Sex-Dependent Susceptibility to Listeria monocytogenes Infection Is Mediated by Differential Interleukin-10 Production
Bastian Pasche, Svetoslav Kalaydjiev, Tobias J. Franz, Elisabeth Kremmer, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabé de Angelis, Andreas Lengeling, Dirk H. Busch
Host Response and Inflammation
Isolation and Partial Purification of Macrophage- and Dendritic Cell-Activating Components from Mycoplasma arthritidis: Association with Organism Virulence and Involvement with Toll-Like Receptor 2
Barry C. Cole, Hong-Hua Mu, Nathan D. Pennock, Akira Hasebe, Fok V. Chan, Leigh R. Washburn, Morgan R. Peltier
Host Response and Inflammation
Paneth Cells and Antibacterial Host Defense in Neonatal Small Intestine
Michael P. Sherman, Stephen H. Bennett, Freda F. Y. Hwang, Jan Sherman, Charles L. Bevins
Host Response and Inflammation
Role of Toll-Like Receptor 4 in the Proinflammatory Response to Vibrio cholerae O1 El Tor Strains Deficient in Production of Cholera Toxin and Accessory Toxins
G. Kenneth Haines, Blayne Amir Sayed, Melissa S. Rohrer, Verena Olivier, Karla J. Fullner Satchell
Host Response and Inflammation
Analysis of Cellular Phenotypes That Mediate Genetic Resistance to Tuberculosis Using a Radiation Bone Marrow Chimera Approach
Konstantin B. Majorov, Evgeny B. Eruslanov, Elvira I. Rubakova, Tatiana K. Kondratieva, Alexander S. Apt

Fungal and Parasitic Infections

Fungal and Parasitic Infections
Gliding Motility Leads to Active Cellular Invasion by Cryptosporidium parvum Sporozoites
Dawn M. Wetzel, Joann Schmidt, Mark S. Kuhlenschmidt, J. P. Dubey, L. David Sibley
Fungal and Parasitic Infections
Sequence Variation and Immunologic Cross-Reactivity among Babesia bovis Merozoite Surface Antigen 1 Proteins from Vaccine Strains and Vaccine Breakthrough Isolates
Tanya LeRoith, Kelly A. Brayton, John B. Molloy, Russell E. Bock, Stephen A. Hines, Ala E. Lew, Terry F. McElwain
Fungal and Parasitic Infections
Cell Surface Heparan Sulfate Promotes Replication of Toxoplasma gondii
Joseph R. Bishop, Brett E. Crawford, Jeffrey D. Esko
Fungal and Parasitic Infections
Identification, Cloning, Expression, and Characterization of the Gene for Plasmodium knowlesi Surface Protein Containing an Altered Thrombospondin Repeat Domain
Babita Mahajan, Dewal Jani, Rana Chattopadhyay, Rana Nagarkatti, Hong Zheng, Victoria Majam, Walter Weiss, Sanjai Kumar, Dharmendar Rathore
Fungal and Parasitic Infections
Involvement of Toll-Like Receptor 2 in Experimental Invasive Pulmonary Aspergillosis
Viviane Balloy, Mustapha Si-Tahar, Osamu Takeuchi, Bruno Philippe, Marie-Anne Nahori, Myriam Tanguy, Michel Huerre, Shizuo Akira, Jean-Paul Latgé, Michel Chignard
Fungal and Parasitic Infections
Iron Acquisition from Transferrin by Candida albicans Depends on the Reductive Pathway
Simon A. B. Knight, Gaston Vilaire, Emmanuel Lesuisse, Andrew Dancis
Fungal and Parasitic Infections
The Aspergillus fumigatus Siderophore Biosynthetic Gene sidA, Encoding l-Ornithine N⁵-Oxygenase, Is Required for Virulence
Anna H. T. Hissen, Adrian N. C. Wan, Mark L. Warwas, Linda J. Pinto, Margo M. Moore
Fungal and Parasitic Infections
Early Cytokine Production Is Associated with Protection from Murine Cerebral Malaria
Andrew J. Mitchell, Anna M. Hansen, Leia Hee, Helen J. Ball, Sarah M. Potter, John C. Walker, Nicholas H. Hunt
Fungal and Parasitic Infections
Calcineurin Is Required for Candida albicans To Survive Calcium Stress in Serum
Jill R. Blankenship, Joseph Heitman
Fungal and Parasitic Infections
Biochemical Characterization and Functional Studies of Acanthamoeba Mannose-Binding Protein
Marco Garate, Ibis Cubillos, Jeffrey Marchant, Noorjahan Panjwani
Fungal and Parasitic Infections
Toward a Novel Experimental Model of Infection To Study American Cutaneous Leishmaniasis Caused by Leishmania braziliensis
Tatiana R. de Moura, Fernanda O. Novais, Fabiano Oliveira, Jorge Clarêncio, Almério Noronha, Aldina Barral, Claudia Brodskyn, Camila I. de Oliveira
Fungal and Parasitic Infections
Vaccination with the Leishmania infantum Acidic Ribosomal P0 Protein plus CpG Oligodeoxynucleotides Induces Protection against Cutaneous Leishmaniasis in C57BL/6 Mice but Does Not Prevent Progressive Disease in BALB/c Mice
Salvador Iborra, Javier Carrión, Charles Anderson, Carlos Alonso, David Sacks, Manuel Soto
Fungal and Parasitic Infections
Placental Malaria Induces Variant-Specific Antibodies of the Cytophilic Subtypes Immunoglobulin G1 (IgG1) and IgG3 That Correlate with Adhesion Inhibitory Activity
Salenna R. Elliott, Amy K. Brennan, James G. Beeson, Eyob Tadesse, Malcolm E. Molyneux, Graham V. Brown, Stephen J. Rogerson
Fungal and Parasitic Infections
Transforming Growth Factor β1 Production by CD4⁺ CD25⁺ Regulatory T Cells in Peripheral Blood Mononuclear Cells from Healthy Subjects Stimulated with Leishmania guyanensis
A. Kariminia, E. Bourreau, H. Pascalis, P. Couppié, D. Sainte-Marie, F. Tacchini-Cottier, P. Launois
Fungal and Parasitic Infections
Extensive Antigenic Polymorphism within the Repeat Sequence of the Plasmodium falciparum Merozoite Surface Protein 1 Block 2 Is Incorporated in a Minimal Polyvalent Immunogen
Kevin K. A. Tetteh, David R. Cavanagh, Patrick Corran, Rosemary Musonda, Jana S. McBride, David J. Conway
Fungal and Parasitic Infections
Merozoite Surface Protein 1 of Plasmodium vivax Induces a Protective Response against Plasmodium cynomolgi Challenge in Rhesus Monkeys
Sheetij Dutta, Deep C. Kaushal, Lisa A. Ware, Sunil K. Puri, Nuzhat A. Kaushal, Atul Narula, D. S. Upadhyaya, David E. Lanar
Fungal and Parasitic Infections
CD8⁺-T-Cell-Dependent Control of Trypanosoma cruzi Infection in a Highly Susceptible Mouse Strain after Immunization with Recombinant Proteins Based on Amastigote Surface Protein 2
Adriano F. S. Araújo, Bruna C. G. de Alencar, José Ronnie C. Vasconcelos, Meire I. Hiyane, Cláudio R. F. Marinho, Marcus L. O. Penido, Silvia B. Boscardin, Daniel F. Hoft, Ricardo T. Gazzinelli, Mauricio M. Rodrigues
Fungal and Parasitic Infections
Arginase I Induction during Leishmania major Infection Mediates the Development of Disease
Virginia Iniesta, Jesualdo Carcelén, Isabel Molano, Pablo M. V. Peixoto, Eloy Redondo, Pilar Parra, Marina Mangas, Isabel Monroy, Maria Luisa Campo, Carlos Gómez Nieto, Inés Corraliza
Fungal and Parasitic Infections
Genome-Wide Expression Profiling in Malaria Infection Reveals Transcriptional Changes Associated with Lethal and Nonlethal Outcomes
Kurt Schaecher, Sanjai Kumar, Anjali Yadava, Maryanne Vahey, Christian F. Ockenhouse
Fungal and Parasitic Infections
Synthesis of Melanin Pigment by Candida albicans In Vitro and during Infection
Rachael Morris-Jones, Beatriz L. Gomez, Soraya Diez, Martha Uran, Stephen D. Morris-Jones, Arturo Casadevall, Joshua D. Nosanchuk, Andrew J. Hamilton
Fungal and Parasitic Infections
CpG Oligodeoxynucleotides Increase the Susceptibility of Normal Mice to Infection by Candida albicans
Shuichi Ito, Joao Pedras-Vasconcelos, Dennis M. Klinman
Fungal and Parasitic Infections
The Anti-Candida albicans Vaccine Composed of the Recombinant N Terminus of Als1p Reduces Fungal Burden and Improves Survival in Both Immunocompetent and Immunocompromised Mice
Brad J. Spellberg, Ashraf S. Ibrahim, Valentina Avenissian, Scott G. Filler, Carter L. Myers, Yue Fu, John E. Edwards

Microbial Immunity and Vaccines

Microbial Immunity and Vaccines
Correlates of Immune Protection in Chickens Vaccinated with Mycoplasma gallisepticum Strain GT5 following Challenge with Pathogenic M. gallisepticum Strain R_low
Mohammed A. Javed, Salvatore Frasca, Debra Rood, Katharine Cecchini, Martha Gladd, Steven J. Geary, Lawrence K. Silbart
Microbial Immunity and Vaccines
Heteropentameric Cholera Toxin B Subunit Chimeric Molecules Genetically Fused to a Vaccine Antigen Induce Systemic and Mucosal Immune Responses: a Potential New Strategy To Target Recombinant Vaccine Antigens to Mucosal Immune Systems
Tetsuya Harakuni, Hideki Sugawa, Ai Komesu, Masayuki Tadano, Takeshi Arakawa
Microbial Immunity and Vaccines
Optimization of Codon Usage Enhances the Immunogenicity of a DNA Vaccine Encoding Mycobacterial Antigen Ag85B
Hyun-Jeong Ko, Sung-Youl Ko, Yeon-Jeong Kim, Eun-Gae Lee, Sang-Nae Cho, Chang-Yuil Kang
Microbial Immunity and Vaccines
Identification of a Protein Subset of the Anthrax Spore Immunome in Humans Immunized with the Anthrax Vaccine Adsorbed Preparation
Indira T. Kudva, Robert W. Griffin, Jeonifer M. Garren, Stephen B. Calderwood, Manohar John
Microbial Immunity and Vaccines
Pulmonary Interleukin-23 Gene Delivery Increases Local T-Cell Immunity and Controls Growth of Mycobacterium tuberculosis in the Lungs
Kyle I. Happel, Euan A. Lockhart, Carol M. Mason, Elizabeth Porretta, Elizabeth Keoshkerian, Anthony R. Odden, Steve Nelson, Alistair J. Ramsay
Microbial Immunity and Vaccines
Pathogenicity and Immunogenicity of a Vaccine Strain of Listeria monocytogenes That Relies on a Suicide Plasmid To Supply an Essential Gene Product
Xinyan Zhao, Zhongxia Li, Baiyan Gu, Fred R. Frankel
Microbial Immunity and Vaccines
HLA-A2 Supertype-Restricted Cell-Mediated Immunity by Peripheral Blood Mononuclear Cells Derived from Malian Children with Severe or Uncomplicated Plasmodium falciparum Malaria and Healthy Controls
Kirsten E. Lyke, Robin B. Burges, Yacouba Cissoko, Lansana Sangare, Abdoulaye Kone, Modibo Dao, Issa Diarra, Marcelo A. Fernández-Viňa, Christopher V. Plowe, Ogobara K. Doumbo, Marcelo B. Sztein
Microbial Immunity and Vaccines
Tracking Antigen-Specific CD8 T Lymphocytes in the Lungs of Mice Vaccinated with the Mtb72F Polyprotein
Scott M. Irwin, Angelo A. Izzo, Steven W. Dow, Y. A. W. Skeiky, Steven G. Reed, Mark R. Alderson, Ian M. Orme
Microbial Immunity and Vaccines
Cationic Liposomes Containing Mycobacterial Lipids: a New Powerful Th1 Adjuvant System
Ida Rosenkrands, Else Marie Agger, Anja W. Olsen, Karen S. Korsholm, Claire Swetman Andersen, Klaus T. Jensen, Peter Andersen
Microbial Immunity and Vaccines
Combined Conjugate Vaccines: Enhanced Immunogenicity with the N19 Polyepitope as a Carrier Protein
Karin Baraldo, Elena Mori, Antonella Bartoloni, Francesco Norelli, Guido Grandi, Rino Rappuoli, Oretta Finco, Giuseppe Del Giudice
Microbial Immunity and Vaccines
Highly Immunogenic and Protective Recombinant Vaccine Candidate Expressed in Transgenic Plants
Daniel Chargelegue, Pascal M. W. Drake, Patricia Obregon, Alessandra Prada, Neil Fairweather, Julian K-C. Ma
Microbial Immunity and Vaccines
Quantitative Assessment of Protection in Experimental Syphilis
Cheryl I. Champion, David R. Blanco, Michael A. Lovett
Microbial Immunity and Vaccines
Humoral and Cell-Mediated Adaptive Immune Responses Are Required for Protection against Burkholderia pseudomallei Challenge and Bacterial Clearance Postinfection
Gareth D. Healey, Stephen J. Elvin, Margaret Morton, E. Diane Williamson
Microbial Immunity and Vaccines
Immunogenicity of Recombinant Protective Antigen and Efficacy against Aerosol Challenge with Anthrax
E. D. Williamson, I. Hodgson, N. J. Walker, A. W. Topping, M. G. Duchars, J. M. Mott, J. Estep, C. LeButt, H. C. Flick-Smith, H. E. Jones, H. Li, C. P. Quinn
Microbial Immunity and Vaccines
Therapeutic Efficacy of High-Dose Intravenous Immunoglobulin in Mycobacterium tuberculosis Infection in Mice
Eleanor Roy, Evangelos Stavropoulos, John Brennan, Stephen Coade, Elena Grigorieva, Barry Walker, Belinda Dagg, Ricardo E. Tascon, Douglas B. Lowrie, M. Joseph Colston, Stephen Jolles
Microbial Immunity and Vaccines
Anamnestic Responses of Mice following Mycobacterium tuberculosis Infection
Arati B. Kamath, Samuel M. Behar
Microbial Immunity and Vaccines
Anti-LcrV Antibody Inhibits Delivery of Yops by Yersinia pestis KIM5 by Directly Promoting Phagocytosis
Clarissa Cowan, Alexander V. Philipovskiy, Christine R. Wulff-Strobel, Zhan Ye, Susan C. Straley
Microbial Immunity and Vaccines
The Protective Effect of Antibody in Immunity to Murine Chlamydial Genital Tract Reinfection Is Independent of Immunoglobulin A
Sandra G. Morrison, Richard P. Morrison

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Cable Pili and the 22-Kilodalton Adhesin Are Required for Burkholderia cenocepacia Binding to and Transmigration across the Squamous Epithelium
Teresa A. Urban, Joanna B. Goldberg, Janet F. Forstner, Umadevi S. Sajjan
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Examination of the Coordinate Effects of Pseudomonas aeruginosa ExoS on Rac1
Claudia L. Rocha, Elizabeth A. Rucks, Deanne M. Vincent, Joan C. Olson
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Salmonella Pathogenicity Island 2-Dependent Expression of Suppressor of Cytokine Signaling 3 in Macrophages
Kei-ichi Uchiya, Toshiaki Nikai
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Cholera Toxin Induces a Transient Depletion of CD8⁺ Intraepithelial Lymphocytes in the Rat Small Intestine as Detected by Microarray and Immunohistochemistry
Carl-Fredrik Flach, Stefan Lange, Eva Jennische, Ivar Lönnroth, Jan Holmgren
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Fetuin-A, a Hepatocyte-Specific Protein That Binds Plasmodium berghei Thrombospondin-Related Adhesive Protein: a Potential Role in Infectivity
Deepa Jethwaney, Timothy Lepore, Saria Hassan, Kerrianne Mello, Radha Rangarajan, Willi Jahnen-Dechent, Dyann Wirth, Ali A. Sultan
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Francisella tularensis Enters Macrophages via a Novel Process Involving Pseudopod Loops
Daniel L. Clemens, Bai-Yu Lee, Marcus A. Horwitz
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Interaction of Enteropathogenic and Shiga Toxin-Producing Escherichia coli and Porcine Intestinal Mucosa: Role of Intimin and Tir in Adherence
Francis Girard, Isabelle Batisson, Gad M. Frankel, Josée Harel, John M. Fairbrother
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Hydrophilic Domain II of Escherichia coli Dr Fimbriae Facilitates Cell Invasion
Margaret Das, Audrey Hart-Van Tassell, Petri T. Urvil, Susan Lea, David Pettigrew, K. L. Anderson, Alfred Samet, Jozef Kur, Steve Matthews, Stella Nowicki, Vsevolod Popov, Pawel Goluszko, Bogdan J. Nowicki
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Mannheimia (Pasteurella) haemolytica Leukotoxin Binding Domain Lies within Amino Acids 1 to 291 of Bovine CD18
R. S. Gopinath, T. C. Ambagala, M. S. Deshpande, R. O. Donis, S. Srikumaran

Bacterial Infections

Bacterial Infections
Experimental Infection Model for Johne's Disease in Sheep
D. J. Begg, R. O'Brien, C. G. Mackintosh, J. F. T. Griffin
Bacterial Infections
Neisseria meningitidis Lactate Permease Is Required for Nasopharyngeal Colonization
Rachel M. Exley, Linda Goodwin, Eva Mowe, Jonathan Shaw, Harry Smith, Robert C. Read, Christoph M. Tang
Bacterial Infections
Identification of Group A Streptococcus Antigenic Determinants Upregulated In Vivo
Kowthar Y. Salim, Dennis G. Cvitkovitch, Peter Chang, Darrin J. Bast, Martin Handfield, Jeffrey D. Hillman, Joyce C. S. de Azavedo
Bacterial Infections
Synergy in Polymicrobial Infections in a Mouse Model of Type 2 Diabetes
Matthew D. Mastropaolo, Nicholas P. Evans, Meghan K. Byrnes, Ann M. Stevens, John L. Robertson, Stephen B. Melville
Bacterial Infections
The Mycobacterium tuberculosis ESAT-6 Homologue in Listeria monocytogenes Is Dispensable for Growth In Vitro and In Vivo
Sing Sing Way, Christopher B. Wilson

Molecular Genomics

Molecular Genomics
Horizontally Acquired Genes for Purine Salvage in Borrelia spp. Causing Relapsing Fever
Alan G. Barbour, Adrienne D. Putteet-Driver, Jonas Bunikis

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Table of Contents

Molecular Pathogenesis

Host Response and Inflammation

Fungal and Parasitic Infections

Microbial Immunity and Vaccines

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions

Bacterial Infections

Molecular Genomics

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