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Molecular Genomics

Constitutive Differences in Gene Expression Profiles Parallel Genetic Patterns of Susceptibility to Tuberculosis in Mice

Marianna O. Orlova, Konstantin B. Majorov, Irina V. Lyadova, Eugenii B. Eruslanov, Cyr E. M'lan, Celia M. T. Greenwood, Erwin Schurr, Alexander S. Apt
Marianna O. Orlova
1Laboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia
2McGill Centre for the Study of Host Resistance, Research Institute of the McGill University Health Centre, Montreal, H3G 1A4 Quebec, Canada
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Konstantin B. Majorov
1Laboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia
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Irina V. Lyadova
1Laboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia
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Eugenii B. Eruslanov
1Laboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia
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Cyr E. M'lan
3Program in Genetics and Genomic Biology, Hospital for Sick Children Research Institute, Toronto, Ontario, Canada
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Celia M. T. Greenwood
3Program in Genetics and Genomic Biology, Hospital for Sick Children Research Institute, Toronto, Ontario, Canada
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Erwin Schurr
2McGill Centre for the Study of Host Resistance, Research Institute of the McGill University Health Centre, Montreal, H3G 1A4 Quebec, Canada
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Alexander S. Apt
1Laboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia
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  • For correspondence: asapt@aha.ru
DOI: 10.1128/IAI.00196-06
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Article Information

DOI 
https://doi.org/10.1128/IAI.00196-06
PubMed 
16714600

Published By 
American Society for Microbiology Journals
History 
  • Received February 3, 2006
  • Returned for modification March 8, 2006
  • Accepted March 16, 2006
  • Published online May 19, 2006.

Copyright & Usage 
Copyright © 2006 American Society for Microbiology

Author Information

  1. Marianna O. Orlova1,2,
  2. Konstantin B. Majorov1,
  3. Irina V. Lyadova1,
  4. Eugenii B. Eruslanov1†,
  5. Cyr E. M'lan3‡,
  6. Celia M. T. Greenwood3,
  7. Erwin Schurr2§ and
  8. Alexander S. Apt1§*
  1. 1Laboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia
  2. 2McGill Centre for the Study of Host Resistance, Research Institute of the McGill University Health Centre, Montreal, H3G 1A4 Quebec, Canada
  3. 3Program in Genetics and Genomic Biology, Hospital for Sick Children Research Institute, Toronto, Ontario, Canada
  • ↵§ Joint senior authors.

  • ↵* Corresponding author. Mailing address: Laboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia. Phone: 7095 268 78 10. Fax: 7095 963 80 00. E-mail: asapt{at}aha.ru .
  • ↵† Present address: Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115.; ‡ Present address: Department of Statistics, University of Connecticut, Storrs, CT 06269.

  • ¶ Supplemental material for this article may be found at http://iai.asm.org/ .

  • Editor: A. D. O'Brien

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Constitutive Differences in Gene Expression Profiles Parallel Genetic Patterns of Susceptibility to Tuberculosis in Mice
Marianna O. Orlova, Konstantin B. Majorov, Irina V. Lyadova, Eugenii B. Eruslanov, Cyr E. M'lan, Celia M. T. Greenwood, Erwin Schurr, Alexander S. Apt
Infection and Immunity May 2006, 74 (6) 3668-3672; DOI: 10.1128/IAI.00196-06

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Constitutive Differences in Gene Expression Profiles Parallel Genetic Patterns of Susceptibility to Tuberculosis in Mice
Marianna O. Orlova, Konstantin B. Majorov, Irina V. Lyadova, Eugenii B. Eruslanov, Cyr E. M'lan, Celia M. T. Greenwood, Erwin Schurr, Alexander S. Apt
Infection and Immunity May 2006, 74 (6) 3668-3672; DOI: 10.1128/IAI.00196-06
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KEYWORDS

Gene Expression Profiling
Genetic Predisposition to Disease
macrophages
tuberculosis

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