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Bacterial Infections

Alanine Esters of Enterococcal Lipoteichoic Acid Play a Role in Biofilm Formation and Resistance to Antimicrobial Peptides

Francesca Fabretti, Christian Theilacker, Lucilla Baldassarri, Zbigniew Kaczynski, Andrea Kropec, Otto Holst, Johannes Huebner
Francesca Fabretti
1Division of Infectious Diseases, Department of Medicine, Freiburg University Hospital, Freiburg, Germany
2Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate-Istituto Superiore di Sanitá, Rome, Italy
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Christian Theilacker
1Division of Infectious Diseases, Department of Medicine, Freiburg University Hospital, Freiburg, Germany
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Lucilla Baldassarri
2Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate-Istituto Superiore di Sanitá, Rome, Italy
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Zbigniew Kaczynski
3Division of Structural Biochemistry, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany
4Department of Chemistry, University of Gdansk, Gdansk, Poland
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Andrea Kropec
1Division of Infectious Diseases, Department of Medicine, Freiburg University Hospital, Freiburg, Germany
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Otto Holst
3Division of Structural Biochemistry, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany
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Johannes Huebner
1Division of Infectious Diseases, Department of Medicine, Freiburg University Hospital, Freiburg, Germany
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  • For correspondence: johannes.huebner@uniklinik-freiburg.de
DOI: 10.1128/IAI.00111-06
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Article Information

DOI 
https://doi.org/10.1128/IAI.00111-06
PubMed 
16790791

Published By 
American Society for Microbiology Journals
History 
  • Received January 22, 2006
  • Returned for modification March 2, 2006
  • Accepted April 20, 2006
  • Published online June 21, 2006.

Copyright & Usage 
Copyright © 2006 American Society for Microbiology

Author Information

  1. Francesca Fabretti1,2,
  2. Christian Theilacker1,
  3. Lucilla Baldassarri2,
  4. Zbigniew Kaczynski3,4,
  5. Andrea Kropec1,
  6. Otto Holst3 and
  7. Johannes Huebner1*
  1. 1Division of Infectious Diseases, Department of Medicine, Freiburg University Hospital, Freiburg, Germany
  2. 2Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate-Istituto Superiore di Sanitá, Rome, Italy
  3. 3Division of Structural Biochemistry, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany
  4. 4Department of Chemistry, University of Gdansk, Gdansk, Poland
  • ↵* Corresponding author. Mailing address: Division of Infectious Diseases, Hugstetter Str. 55, 79106 Freiburg, Germany. Phone: 49-761-270-1828. Fax: 49-761-270-1820. E-mail: johannes.huebner{at}uniklinik-freiburg.de .
  • Editor: J. N. Weiser

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Alanine Esters of Enterococcal Lipoteichoic Acid Play a Role in Biofilm Formation and Resistance to Antimicrobial Peptides
Francesca Fabretti, Christian Theilacker, Lucilla Baldassarri, Zbigniew Kaczynski, Andrea Kropec, Otto Holst, Johannes Huebner
Infection and Immunity Jun 2006, 74 (7) 4164-4171; DOI: 10.1128/IAI.00111-06

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Alanine Esters of Enterococcal Lipoteichoic Acid Play a Role in Biofilm Formation and Resistance to Antimicrobial Peptides
Francesca Fabretti, Christian Theilacker, Lucilla Baldassarri, Zbigniew Kaczynski, Andrea Kropec, Otto Holst, Johannes Huebner
Infection and Immunity Jun 2006, 74 (7) 4164-4171; DOI: 10.1128/IAI.00111-06
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KEYWORDS

Alanine
Antimicrobial Cationic Peptides
biofilms
Drug Resistance, Bacterial
Enterococcus faecalis
Lipopolysaccharides
teichoic acids

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