Infection and Immunity: 75 (11)

November 2007; Volume 75,Issue 11

Spotlight

Free

Spotlight
Articles of Significant Interest Selected from This Issue by the Editors

Guest Commentary

GUEST COMMENTARY
Antibody-Mediated Protection through Cross-Reactivity Introduces a Fungal Heresy into Immunological Dogma
Arturo Casadevall, Liise-anne Pirofski

Minireviews

Minireview
MARTX, Multifunctional Autoprocessing Repeats-in-Toxin Toxins
Karla J. Fullner Satchell

Fungal and Parasitic Infections

Fungal and Parasitic Infections
An Anti-β-Glucan Monoclonal Antibody Inhibits Growth and Capsule Formation of Cryptococcus neoformans In Vitro and Exerts Therapeutic, Anticryptococcal Activity In Vivo
Anna Rachini, Donatella Pietrella, Patrizia Lupo, Antonella Torosantucci, Paola Chiani, Carla Bromuro, Carla Proietti, Francesco Bistoni, Antonio Cassone, Anna Vecchiarelli
Fungal and Parasitic Infections
Taenia solium Oncosphere Adhesion to Intestinal Epithelial and Chinese Hamster Ovary Cells In Vitro
Manuela Verastegui, Robert H. Gilman, Yanina Arana, Dylan Barber, Jeanette Velásquez, Marilu Farfán, Nancy Chile, Jon C. Kosek, Margaret Kosek, Hector H. Garcia, Armando Gonzalez
and and the Cysticercosis Working Group in Peru
Fungal and Parasitic Infections
Presentation of Toxoplasma gondii Antigens via the Endogenous Major Histocompatibility Complex Class I Pathway in Nonprofessional and Professional Antigen-Presenting Cells
Florence Dzierszinski, Marion Pepper, Jason S. Stumhofer, David F. LaRosa, Emma H. Wilson, Laurence A. Turka, Sandra K. Halonen, Christopher A. Hunter, David S. Roos
Fungal and Parasitic Infections
Protective Properties and Surface Localization of Plasmodium falciparum Enolase
Ipsita Pal-Bhowmick, Monika Mehta, Isabelle Coppens, Shobhona Sharma, Gotam K. Jarori
Fungal and Parasitic Infections
Direct Microscopic Quantification of Dynamics of Plasmodium berghei Sporozoite Transmission from Mosquitoes to Mice
Yamei Jin, Chahnaz Kebaier, Jerome Vanderberg

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Two Domains of Cytotoxic Necrotizing Factor Type 1 Bind the Cellular Receptor, Laminin Receptor Precursor Protein
Beth A. McNichol, Susan B. Rasmussen, Humberto M. Carvalho, Karen C. Meysick, Alison D. O'Brien
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Severe Tryptophan Starvation Blocks Onset of Conventional Persistence and Reduces Reactivation of Chlamydia trachomatis
Ralf M. Leonhardt, Seung-Joon Lee, Paula B. Kavathas, Peter Cresswell
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | Spotlight
Coxiella burnetii Inhibits Activation of Host Cell Apoptosis through a Mechanism That Involves Preventing Cytochrome c Release from Mitochondria
Anja Lührmann, Craig R. Roy
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Analysis of the In Vitro Transcriptional Response of Human Pharyngeal Epithelial Cells to Adherent Streptococcus pneumoniae: Evidence for a Distinct Response to Encapsulated Strains
Hester J. Bootsma, Michael Egmont-Petersen, Peter W. M. Hermans

Host Response and Inflammation

Host Response and Inflammation
Expression of Helicobacter pylori Virulence Factors and Associated Expression Profiles of Inflammatory Genes in the Human Gastric Mucosa
Sicheng Wen, Dominique Velin, Christian P. Felley, Likun Du, Pierre Michetti, Qiang Pan-Hammarström
Host Response and Inflammation
Nucleotide-Binding Oligomerization Domain Protein 2-Deficient Mice Control Infection with Mycobacterium tuberculosis
Sheetal Gandotra, Sihyug Jang, Peter J. Murray, Padmini Salgame, Sabine Ehrt
Host Response and Inflammation
Galectin-3 Modulates Immune and Inflammatory Responses during Helminthic Infection: Impact of Galectin-3 Deficiency on the Functions of Dendritic Cells
Laetitia Breuilh, François Vanhoutte, Josette Fontaine, Caroline M. W. van Stijn, Isabelle Tillie-Leblond, Monique Capron, Christelle Faveeuw, Thierry Jouault, Irma van Die, Philippe Gosset, François Trottein
Host Response and Inflammation
Impaired Expression of Perforin and Granulysin in CD8⁺ T Cells at the Site of Infection in Human Chronic Pulmonary Tuberculosis
Jan Andersson, Arina Samarina, Joshua Fink, Sayma Rahman, Susanna Grundström
Host Response and Inflammation
Helicobacter pylori Induces CCL20 Expression
Koh Tomimori, Eriko Uema, Hiromitsu Teruya, Chie Ishikawa, Taeko Okudaira, Masachika Senba, Kazuo Yamamoto, Toshifumi Matsuyama, Fukunori Kinjo, Jiro Fujita, Naoki Mori
Host Response and Inflammation
Mycobacterium tuberculosis-Induced Gamma Interferon Production by Natural Killer Cells Requires Cross Talk with Antigen-Presenting Cells Involving Toll-Like Receptors 2 and 4 and the Mannose Receptor in Tuberculous Pleurisy
Pablo Schierloh, Noemí Yokobori, Mercedes Alemán, Verónica Landoni, Laura Geffner, Rosa M. Musella, Jorge Castagnino, Matias Baldini, Eduardo Abbate, Silvia S. de la Barrera, María C. Sasiain
Host Response and Inflammation
Toll-Like Receptor 2 Controls the Gamma Interferon Response to Francisella tularensis by Mouse Liver Lymphocytes
Kee-Jong Hong, Jason R. Wickstrum, Hung-Wen Yeh, Michael J. Parmely
Host Response and Inflammation
Constitutive Acid Sphingomyelinase Enhances Early and Late Macrophage Killing of Salmonella enterica Serovar Typhimurium
Bruce D. McCollister, Jesse T. Myers, Jessica Jones-Carson, Dennis R. Voelker, Andrés Vázquez-Torres
Host Response and Inflammation
Modulation of Host Innate Immune Response in the Bladder by Uropathogenic Escherichia coli
Benjamin K. Billips, Sarah G. Forrestal, Matthew T. Rycyk, James R. Johnson, David J. Klumpp, Anthony J. Schaeffer
Host Response and Inflammation
Differential Contribution of Bacterial N-Formyl-Methionyl-Leucyl- Phenylalanine and Host-Derived CXC Chemokines to Neutrophil Infiltration into Pulmonary Alveoli during Murine Pneumococcal Pneumonia
Jean-François Gauthier, Andrée Fortin, Yves Bergeron, Marie-Christine Dumas, Marie-Eve Champagne, Michel G. Bergeron
Host Response and Inflammation
Identification of LpxL, a Late Acyltransferase of Francisella tularensis
Molly K. McLendon, Birgit Schilling, Jason R. Hunt, Michael A. Apicella, Bradford W. Gibson

Molecular Pathogenesis

Molecular Pathogenesis
Listeriolysin O Secreted by Listeria monocytogenes into the Host Cell Cytosol Is Degraded by the N-End Rule Pathway
Pamela Schnupf, Jianmin Zhou, Alexander Varshavsky, Daniel A. Portnoy
Molecular Pathogenesis
Identification and Isolation of Brucella suis Virulence Genes Involved in Resistance to the Human Innate Immune System
Janny Liautard, Safia Ouahrani-Bettache, Véronique Jubier-Maurin, Virginie Lafont, Stephan Köhler, Jean-Pierre Liautard
Molecular Pathogenesis
Anthrax Protective Antigen Cleavage and Clearance from the Blood of Mice and Rats
Mahtab Moayeri, Jason F. Wiggins, Stephen H. Leppla
Molecular Pathogenesis | Spotlight
Maintenance of Antibody to Pathogen Epitopes Generated by Segmental Gene Conversion Is Highly Dynamic during Long-Term Persistent Infection
Yan Zhuang, James E. Futse, Wendy C. Brown, Kelly A. Brayton, Guy H. Palmer
Molecular Pathogenesis
Brucella abortus Requires the Heme Transporter BhuA for Maintenance of Chronic Infection in BALB/c Mice
James T. Paulley, Eric S. Anderson, R. Martin Roop
Molecular Pathogenesis
Characterization of an Immunogenic Outer Membrane Autotransporter Protein, Arp, of Bartonella henselae
Christine M. Litwin, Mindy L. Rawlins, Erica M. Swenson
Molecular Pathogenesis
Contribution of the stg Fimbrial Operon of Salmonella enterica Serovar Typhi during Interaction with Human Cells
Chantal Forest, Sébastien P. Faucher, Katherine Poirier, Sébastien Houle, Charles M. Dozois, France Daigle
Molecular Pathogenesis
Delineation of Species-Specific Binding Properties of the CspZ Protein (BBH06) of Lyme Disease Spirochetes: Evidence for New Contributions to the Pathogenesis of Borrelia spp.
Elizabeth A. Rogers, Richard T. Marconi
Molecular Pathogenesis
Identification of Francisella tularensis Himar1-Based Transposon Mutants Defective for Replication in Macrophages
Tamara M. Maier, Monika S. Casey, Rachel H. Becker, Caleb W. Dorsey, Elizabeth M. Glass, Natalia Maltsev, Thomas C. Zahrt, Dara W. Frank
Molecular Pathogenesis
Enterococcus faecalis Constitutes an Unusual Bacterial Model in Lysozyme Resistance
Laurent Hébert, Pascal Courtin, Riccardo Torelli, Maurizio Sanguinetti, Marie-Pierre Chapot-Chartier, Yanick Auffray, Abdellah Benachour
Molecular Pathogenesis
Relative Contributions of Enterococcus faecalis OG1RF Sortase-Encoding Genes, srtA and bps (srtC), to Biofilm Formation and a Murine Model of Urinary Tract Infection
Kelvin D. Kemp, Kavindra V. Singh, Sreedhar R. Nallapareddy, Barbara E. Murray
Molecular Pathogenesis
The Surface Protein Srr-1 of Streptococcus agalactiae Binds Human Keratin 4 and Promotes Adherence to Epithelial HEp-2 Cells
Ulrike Samen, Bernhard J. Eikmanns, Dieter J. Reinscheid, Frédéric Borges
Molecular Pathogenesis
The Mycobacterium bovis BCG Cyclic AMP Receptor-Like Protein Is a Functional DNA Binding Protein In Vitro and In Vivo, but Its Activity Differs from That of Its M. tuberculosis Ortholog, Rv3676
Guangchun Bai, Michaela A. Gazdik, Damen D. Schaak, Kathleen A. McDonough

Bacterial Infections

Bacterial Infections | Spotlight
Systemic Translocation of Salmonella enterica Serovar Dublin in Cattle Occurs Predominantly via Efferent Lymphatics in a Cell-Free Niche and Requires Type III Secretion System 1 (T3SS-1) but Not T3SS-2
Gillian D. Pullinger, Susan M. Paulin, Bryan Charleston, Patricia R. Watson, Alison J. Bowen, Francis Dziva, Eirwen Morgan, Bernardo Villarreal-Ramos, Timothy S. Wallis, Mark P. Stevens
Bacterial Infections
Bacillus anthracis Exosporium Protein BclA Affects Spore Germination, Interaction with Extracellular Matrix Proteins, and Hydrophobicity
Trupti N. Brahmbhatt, Brian K. Janes, E. Scott Stibitz, Stephen C. Darnell, Patrick Sanz, Susan B. Rasmussen, Alison D. O'Brien
Bacterial Infections
Antigen-Specific Cellular and Humoral Responses Are Induced by Intradermal Mycobacterium leprae Infection of the Mouse Ear
Malcolm S. Duthie, Stephen T. Reece, Ramanuj Lahiri, Wakako Goto, Vanitha S. Raman, Juliette Kaplan, Greg C. Ireton, Sylvie Bertholet, Thomas P. Gillis, James L. Krahenbuhl, Steven G. Reed
Bacterial Infections
Roles of Serine Accumulation and Catabolism in the Colonization of the Murine Urinary Tract by Escherichia coli CFT073
Andrew T. Anfora, Brian J. Haugen, Paula Roesch, Peter Redford, Rodney A. Welch
Bacterial Infections
Impact of Alcaligin Siderophore Utilization on In Vivo Growth of Bordetella pertussis
Timothy J. Brickman, Sandra K. Armstrong
Bacterial Infections
In Vivo Evidence of Pseudomonas aeruginosa Nutrient Acquisition and Pathogenesis in the Lungs of Cystic Fibrosis Patients
Mike S. Son, Wallace J. Matthews, Yun Kang, David T. Nguyen, Tung T. Hoang
Bacterial Infections
Role of CD14 in Responses to Clinical Isolates of Escherichia coli: Effects of K1 Capsule Expression
Shalaka Metkar, Shanjana Awasthi, Erick Denamur, Kwang Sik Kim, Sophie C. Gangloff, Saul Teichberg, Alain Haziot, Jack Silver, Sanna M. Goyert
Bacterial Infections | Spotlight
l-Fucose Stimulates Utilization of d-Ribose by Escherichia coli MG1655 ΔfucAO and E. coli Nissle 1917 ΔfucAO Mutants in the Mouse Intestine and in M9 Minimal Medium
Steven M. Autieri, Jeremy J. Lins, Mary P. Leatham, David C. Laux, Tyrrell Conway, Paul S. Cohen

Microbial Immunity and Vaccines

Microbial Immunity and Vaccines
Recombinant Exosporium Protein BclA of Bacillus anthracis Is Effective as a Booster for Mice Primed with Suboptimal Amounts of Protective Antigen
Trupti N. Brahmbhatt, Stephen C. Darnell, Humberto M. Carvalho, Patrick Sanz, Tae J. Kang, Robert L. Bull, Susan B. Rasmussen, Alan S. Cross, Alison D. O'Brien
Microbial Immunity and Vaccines
Effects of DNA- and Mycobacterium bovis BCG-Based Delivery of the Flt3 Ligand on Protective Immunity to Mycobacterium tuberculosis
James A. Triccas, Elena Shklovskaya, Joanne Spratt, Anthony A. Ryan, Umaimainthan Palendira, Barbara Fazekas de StGroth, Warwick J. Britton
Microbial Immunity and Vaccines
Human Monoclonal Antibodies against Anthrax Lethal Factor and Protective Antigen Act Independently To Protect against Bacillus anthracis Infection and Enhance Endogenous Immunity to Anthrax
Mark T. Albrecht, Han Li, E. Diane Williamson, Chris S. LeButt, Helen C. Flick-Smith, Conrad P. Quinn, Hans Westra, Darrell Galloway, Alfred Mateczun, Stanley Goldman, Herman Groen, Les W. J. Baillie
Microbial Immunity and Vaccines
Additive and Synergistic Bactericidal Activity of Antibodies Directed against Minor Outer Membrane Proteins of Neisseria meningitidis
Vincent E. Weynants, Christiane M. Feron, Karine K. Goraj, Martine P. Bos, Philippe A. Denoël, Vincent G. Verlant, Jan Tommassen, Ian R. A. Peak, Ralph C. Judd, Michael P. Jennings, Jan T. Poolman
Microbial Immunity and Vaccines
In Vitro and In Vivo Characterization of Anthrax Anti-Protective Antigen and Anti-Lethal Factor Monoclonal Antibodies after Passive Transfer in a Mouse Lethal Toxin Challenge Model To Define Correlates of Immunity
Herman F. Staats, S. Munir Alam, Richard M. Scearce, Shaun M. Kirwan, Julia Xianzhi Zhang, William M. Gwinn, Barton F. Haynes
Microbial Immunity and Vaccines
CD4 T-Cell Epitopes Associated with Protective Immunity Induced following Vaccination of Mice with an Ehrlichial Variable Outer Membrane Protein
Bisweswar Nandi, Kathryn Hogle, Nicholas Vitko, Gary M. Winslow
Microbial Immunity and Vaccines
Antibody-Independent, CD4⁺ T-Cell-Dependent Protection against Pneumococcal Colonization Elicited by Intranasal Immunization with Purified Pneumococcal Proteins
Alan Basset, Claudette M. Thompson, Susan K. Hollingshead, David E. Briles, Edwin W. Ades, Marc Lipsitch, Richard Malley
Microbial Immunity and Vaccines
Construction and Characterization of Single-Chain Variable Fragment Antibodies Directed against the Bordetella pertussis Surface Adhesins Filamentous Hemagglutinin and Pertactin
Ahmad H. Hussein, Elisabeth M. Davis, Scott A. Halperin, Song F. Lee

Molecular Genomics

Molecular Genomics
Characterization of a New Variant of IS257 That Has Displaced the Capsule Genes within Bovine Isolates of Staphylococcus aureus
L. P. N. Tuchscherr, M. I. Gomez, F. R. Buzzola, L. F. Calvinho, J. C. Lee, D. O. Sordelli

Main menu

User menu

Search

Table of Contents

Spotlight

Guest Commentary

Minireviews

Fungal and Parasitic Infections

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions

Host Response and Inflammation

Molecular Pathogenesis

Bacterial Infections

Microbial Immunity and Vaccines

Molecular Genomics

In This Issue

Jump to