Skip to main content
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems
  • Log in
  • My alerts
  • My Cart

Main menu

  • Home
  • Articles
    • Current Issue
    • Accepted Manuscripts
    • Archive
    • Minireviews
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About IAI
    • Editor in Chief
    • Editorial Board
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ
  • Subscribe
    • Members
    • Institutions
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems

User menu

  • Log in
  • My alerts
  • My Cart

Search

  • Advanced search
Infection and Immunity
publisher-logosite-logo

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Accepted Manuscripts
    • Archive
    • Minireviews
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About IAI
    • Editor in Chief
    • Editorial Board
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ
  • Subscribe
    • Members
    • Institutions

Table of Contents

February 2007; Volume 75,Issue 2

Spotlight

  • Free
    Spotlight
    Articles of Significant Interest Selected from This Issue by the Editors

Minireviews

  • Minireview
    How Flagellin and Toll-Like Receptor 5 Contribute to Enteric Infection
    Theodore S. Steiner

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions

  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Differences in Chlamydia trachomatis Serovar E Growth Rate in Polarized Endometrial and Endocervical Epithelial Cells Grown in Three-Dimensional Culture
    Natalia V. Guseva, Sophie Dessus-Babus, Cheryl G. Moore, Judy D. Whittimore, Priscilla B. Wyrick
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Enteropathogenic Escherichia coli, Shigella flexneri, and Listeria monocytogenes Recruit a Junctional Protein, Zonula Occludens-1, to Actin Tails and Pedestals
    Miyuki Hanajima-Ozawa, Takeshi Matsuzawa, Aya Fukui, Shigeki Kamitani, Hiroe Ohnishi, Akio Abe, Yasuhiko Horiguchi, Masami Miyake
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    SseL Is a Salmonella-Specific Translocated Effector Integrated into the SsrB-Controlled Salmonella Pathogenicity Island 2 Type III Secretion System
    Brian K. Coombes, Michael J. Lowden, Jennifer L. Bishop, Mark E. Wickham, Nat F. Brown, Nancy Duong, Suzanne Osborne, Ohad Gal-Mor, B. Brett Finlay
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    A Mycobacterial Gene Involved in Synthesis of an Outer Cell Envelope Lipid Is a Key Factor in Prevention of Phagosome Maturation
    Nirmal Robinson, Martina Wolke, Karen Ernestus, Georg Plum
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    The Legionella pneumophila Effector SidJ Is Required for Efficient Recruitment of Endoplasmic Reticulum Proteins to the Bacterial Phagosome
    Yancheng Liu, Zhao-Qing Luo
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | Spotlight
    Chlamydia pneumoniae-Induced Macrophage Foam Cell Formation Is Mediated by Toll-Like Receptor 2
    Fei Cao, Antonio Castrillo, Peter Tontonoz, Fabio Re, Gerald I. Byrne
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | Spotlight
    The Rab6 Effector Bicaudal D1 Associates with Chlamydia trachomatis Inclusions in a Biovar-Specific Manner
    A. R. Moorhead, K. A. Rzomp, M. A. Scidmore
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Difference in the Cytotoxic Effects of Toxin B from Clostridium difficile Strain VPI 10463 and Toxin B from Variant Clostridium difficile Strain 1470
    Johannes Huelsenbeck, Stefanie Dreger, Ralf Gerhard, Holger Barth, Ingo Just, Harald Genth
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Differential Abilities of Capsulated and Noncapsulated Staphylococcus aureus Isolates from Diverse agr Groups To Invade Mammary Epithelial Cells
    Fernanda R. Buzzola, Lucía P. Alvarez, Lorena P. N. Tuchscherr, María S. Barbagelata, Santiago M. Lattar, Luis Calvinho, Daniel O. Sordelli
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Differential Activation of Human Gingival Epithelial Cells and Monocytes by Porphyromonas gingivalis Fimbriae
    Mehmet A. Eskan, George Hajishengallis, Denis F. Kinane
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Evidence for an Intramacrophage Growth Phase of Mycobacterium ulcerans
    Egídio Torrado, Alexandra G. Fraga, António G. Castro, Pieter Stragier, Wayne M. Meyers, Françoise Portaels, Manuel T. Silva, Jorge Pedrosa
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Protective Effect of the Nramp1 BB Genotype against Brucella abortus in the Water Buffalo (Bubalus bubalis)
    Rosanna Capparelli, Flora Alfano, Maria Grazia Amoroso, Giorgia Borriello, Domenico Fenizia, Antonio Bianco, Sante Roperto, Franco Roperto, Domenico Iannelli
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Role of the Lipopolysaccharide-CD14 Complex for the Activity of Hemolysin from Uropathogenic Escherichia coli
    Lisa E. Månsson, Peter Kjäll, Shahaireen Pellett, Gábor Nagy, Rodney A. Welch, Fredrik Bäckhed, Teresa Frisan, Agneta Richter-Dahlfors

Molecular Pathogenesis

  • Molecular Pathogenesis | Spotlight
    TccP2 of O157:H7 and Non-O157 Enterohemorrhagic Escherichia coli (EHEC): Challenging the Dogma of EHEC-Induced Actin Polymerization
    Yoshitoshi Ogura, Tadasuke Ooka, Andrew Whale, Junkal Garmendia, Lothar Beutin, Sharon Tennant, Gladys Krause, Stefano Morabito, Isabel Chinen, Toru Tobe, Hiroyuki Abe, Rosangela Tozzoli, Alfredo Caprioli, Marta Rivas, Roy Robins-Browne, Tetsuya Hayashi, Gad Frankel
  • Molecular Pathogenesis | Spotlight
    Environmental Mimics and the Lvh Type IVA Secretion System Contribute to Virulence-Related Phenotypes of Legionella pneumophila
    Purnima Bandyopadhyay, Shuqing Liu, Carolina B. Gabbai, Zeah Venitelli, Howard M. Steinman
  • Molecular Pathogenesis | Spotlight
    Differential Liver Protein Expression during Schistosomiasis
    Marina Harvie, Thomas William Jordan, Anne Camille La Flamme
  • Molecular Pathogenesis
    Iron-Responsive Repression of Urease Expression in Helicobacter hepaticus Is Mediated by the Transcriptional Regulator Fur
    Clara Belzer, Bart A. M. van Schendel, Ernst J. Kuipers, Johannes G. Kusters, Arnoud H. M. van Vliet
  • Molecular Pathogenesis
    Comparative Analysis of the Abilities of Shiga Toxins 1 and 2 To Bind to and Influence Neutrophil Apoptosis
    Michael J. Flagler, Jane E. Strasser, Claudia L. Chalk, Alison A. Weiss
  • Molecular Pathogenesis
    Characterization of the Outer Membrane Proteome of Leptospira interrogans Expressed during Acute Lethal Infection
    Jarlath E. Nally, Julian P. Whitelegge, Sara Bassilian, David R. Blanco, Michael A. Lovett
  • Molecular Pathogenesis
    Characterization of the Urease Operon of Brucella abortus and Assessment of Its Role in Virulence of the Bacterium
    Félix J. Sangari, Asunción Seoane, María Cruz Rodríguez, Jesús Agüero, Juan M. García Lobo
  • Molecular Pathogenesis
    Growth Condition-Dependent Esp Expression by Enterococcus faecium Affects Initial Adherence and Biofilm Formation
    Willem J. B. Van Wamel, Antoni P. A. Hendrickx, Marc J. M. Bonten, Janetta Top, George Posthuma, Rob J. L. Willems
  • Molecular Pathogenesis
    ActA Is Required for Crossing of the Fetoplacental Barrier by Listeria monocytogenes
    Alban Le Monnier, Nicolas Autret, Olivier F. Join-Lambert, Francis Jaubert, Alain Charbit, Patrick Berche, Samer Kayal
  • Molecular Pathogenesis
    Phosphorylcholine Decreases Early Inflammation and Promotes the Establishment of Stable Biofilm Communities of Nontypeable Haemophilus influenzae Strain 86-028NP in a Chinchilla Model of Otitis Media
    Wenzhou Hong, Kevin Mason, Joseph Jurcisek, Laura Novotny, Lauren O. Bakaletz, W. Edward Swords
  • Molecular Pathogenesis
    Global Gene Expression Profiling of Asymptomatic Bacteriuria Escherichia coli during Biofilm Growth in Human Urine
    Viktoria Hancock, Per Klemm
  • Molecular Pathogenesis
    Expression of Phosphorylcholine by Histophilus somni Induces BovinePlatelet Aggregation
    Christopher J. Kuckleburg, Shaadi F. Elswaifi, Thomas J. Inzana, Charles J. Czuprynski
  • Molecular Pathogenesis
    Identification of the Gene Encoding the FhbB Protein of Treponema denticola, a Highly Unique Factor H-Like Protein 1 Binding Protein
    John V. McDowell, Jesse Frederick, Lola Stamm, Richard T. Marconi

Host Response and Inflammation

  • Host Response and Inflammation
    Recruitment of Macrophages and Polymorphonuclear Leukocytes in Lyme Carditis
    Ruth R. Montgomery, Carmen J. Booth, Xiaomei Wang, Victoria A. Blaho, Stephen E. Malawista, Charles R. Brown
  • Host Response and Inflammation | Spotlight
    Mutants of Type II Heat-Labile Enterotoxin LT-IIa with Altered Ganglioside-Binding Activities and Diminished Toxicity Are Potent Mucosal Adjuvants
    Hesham F. Nawar, Sergio Arce, Michael W. Russell, Terry D. Connell
  • Host Response and Inflammation
    Delayed Inflammatory Response to Primary Pneumonic Plague Occurs in Both Outbred and Inbred Mice
    Sarah S. Bubeck, Angelene M. Cantwell, Peter H. Dube
  • Host Response and Inflammation | Spotlight
    Modification of the Structure of Peptidoglycan Is a Strategy To Avoid Detection by Nucleotide-Binding Oligomerization Domain Protein 1
    Margreet A. Wolfert, Abhijit Roychowdhury, Geert-Jan Boons
  • Host Response and Inflammation
    Chronic Exposure to Helicobacter pylori Impairs Dendritic Cell Function and Inhibits Th1 Development
    Peter Mitchell, Conrad Germain, Pier Luigi Fiori, Wafa Khamri, Graham R. Foster, Subrata Ghosh, Robert I. Lechler, Kathleen B. Bamford, Giovanna Lombardi
  • Host Response and Inflammation
    Dynamic Changes in Pro- and Anti-Inflammatory Cytokine Profiles and Gamma Interferon Receptor Signaling Integrity Correlate with Tuberculosis Disease Activity and Response to Curative Treatment
    Edhyana Sahiratmadja, Bachti Alisjahbana, Tjitske de Boer, Iskandar Adnan, Anugrah Maya, Halim Danusantoso, Ronald H. H. Nelwan, Sangkot Marzuki, Jos W. M. van der Meer, Reinout van Crevel, Esther van de Vosse, Tom H. M. Ottenhoff
  • Host Response and Inflammation | Spotlight
    Contribution of Phagocytosis and Intracellular Sensing for Cytokine Production by Staphylococcus aureus-Activated Macrophages
    Ronan Kapetanovic, Marie-Anne Nahori, Viviane Balloy, Catherine Fitting, Dana J. Philpott, Jean-Marc Cavaillon, Minou Adib-Conquy
  • Host Response and Inflammation
    Gene Expression Pattern in Human Brain Endothelial Cells in Response to Neisseria meningitidis
    Alexandra Schubert-Unkmeir, Olga Sokolova, Ursula Panzner, Martin Eigenthaler, Matthias Frosch
  • Host Response and Inflammation
    Immunogenicity of Eight Dormancy Regulon-Encoded Proteins of Mycobacterium tuberculosis in DNA-Vaccinated and Tuberculosis-Infected Mice
    Virginie Roupie, Marta Romano, Lei Zhang, Hannelie Korf, May Young Lin, Kees L. M. C. Franken, Tom H. M. Ottenhoff, Michèl R. Klein, Kris Huygen

Fungal and Parasitic Infections

  • Fungal and Parasitic Infections
    Infection with Toxoplasma gondii Bradyzoites Has a Diminished Impact on Host Transcript Levels Relative to Tachyzoite Infection
    A. E. Fouts, J. C. Boothroyd
  • Fungal and Parasitic Infections
    Expression of Merozoite Surface Protein Markers by Plasmodium falciparum-Infected Erythrocytes in Peripheral Blood and Tissues of Children with Fatal Malaria
    Carlota Dobaño, Stephen J. Rogerson, Terrie E. Taylor, Jana S. McBride, Malcolm E. Molyneux
  • Fungal and Parasitic Infections
    Leishmania-Derived Murine Monocyte Chemoattractant Protein 1 Enhances the Recruitment of a Restrictive Population of CC Chemokine Receptor 2-Positive Macrophages
    Sean M. Conrad, Dalit Strauss-Ayali, Ann E. Field, Matthias Mack, David M. Mosser
  • Fungal and Parasitic Infections
    The Human Immunodeficiency Virus Type 1 Tat Protein Enhances Cryptosporidium parvum-Induced Apoptosis in Cholangiocytes via a Fas Ligand-Dependent Mechanism
    Steven P. O'Hara, Aaron J. Small, Jeremy B. Nelson, Andrew D. Badley, Xian-Ming Chen, Gregory J. Gores, Nicholas F. LaRusso
  • Fungal and Parasitic Infections
    Cell Wall Targeting of Laccase of Cryptococcus neoformans during Infection of Mice
    Scott R. Waterman, Moshe Hacham, John Panepinto, Guowu Hu, Soowan Shin, Peter R. Williamson
  • Fungal and Parasitic Infections | Spotlight
    Murine Immune Responses to Liver-Stage Antigen 1 Protein FMP011, a Malaria Vaccine Candidate, Delivered with Adjuvant AS01B or AS02A
    Clara Brando, Lisa A. Ware, Helen Freyberger, April Kathcart, Arnoldo Barbosa, Sylvie Cayphas, Marie-Ange Demoitie, Pascal Mettens, D. Gray Heppner, David E. Lanar
  • Fungal and Parasitic Infections | Spotlight
    Bioinformatic Identification of Tandem Repeat Antigens of the Leishmania donovani Complex
    Yasuyuki Goto, Rhea N. Coler, Steven G. Reed
  • Fungal and Parasitic Infections
    Heterologous Priming-Boosting with DNA and Modified Vaccinia Virus Ankara Expressing Tryparedoxin Peroxidase Promotes Long-Term Memory against Leishmania major in Susceptible BALB/c Mice
    Carmel B. Stober, Uta G. Lange, Mark T. M. Roberts, Antonio Alcami, Jenefer M. Blackwell
  • Fungal and Parasitic Infections
    Endogenous CD4+ CD25+ Regulatory T Cells Have a Limited Role in the Control of Trypanosoma cruzi Infection in Mice
    Joshua Kotner, Rick Tarleton
  • Fungal and Parasitic Infections
    Oxidant Generation by Single Infected Monocytes after Short-Term Fluorescence Labeling of a Protozoan Parasite
    Haeok K. Chang, Colin Thalhofer, Breck A. Duerkop, Joanna S. Mehling, Shilpi Verma, Kenneth J. Gollob, Roque Almeida, Mary E. Wilson

Microbial Immunity and Vaccines

  • Microbial Immunity and Vaccines
    Intranasal Vaccination with a Secreted Chlamydial Protein Enhances Resolution of Genital Chlamydia muridarum Infection, Protects against Oviduct Pathology, and Is Highly Dependent upon Endogenous Gamma Interferon Production
    Ashlesh K. Murthy, James P. Chambers, Patricia A. Meier, Guangming Zhong, Bernard P. Arulanandam
  • Microbial Immunity and Vaccines
    Therapeutic Chlamydophila abortus and C. pecorum Vaccination Transiently Reduces Bovine Mastitis Associated with Chlamydophila Infection
    Carolin Biesenkamp-Uhe, Yihang Li, Hans-Robert Hehnen, Konrad Sachse, Bernhard Kaltenboeck
  • Microbial Immunity and Vaccines
    Vaccination with Live Yersinia pestis Primes CD4 and CD8 T Cells That Synergistically Protect against Lethal Pulmonary Y. pestis Infection
    Alexander V. Philipovskiy, Stephen T. Smiley
  • Microbial Immunity and Vaccines
    Immunogenic and Protective Potential of Mutans Streptococcal Glucosyltransferase Peptide Constructs Selected by Major Histocompatibility Complex Class II Allele Binding
    S. Culshaw, K. LaRosa, H. Tolani, X. Han, J. W. Eastcott, D. J. Smith, M. A. Taubman
  • Microbial Immunity and Vaccines
    Affinity-Purified Human Immunoglobulin G That Binds a Lacto-N-Neotetraose-Dependent Lipooligosaccharide Structure Is Bactericidal for Serogroup B Neisseria meningitidis
    Michele M. Estabrook, Gary A. Jarvis, J. McLeod Griffiss
  • Microbial Immunity and Vaccines
    Streptococcus pneumoniae Pilus Subunits Protect Mice against Lethal Challenge
    Claudia Gianfaldoni, Stefano Censini, Markus Hilleringmann, Monica Moschioni, Claudia Facciotti, Werner Pansegrau, Vega Masignani, Antonello Covacci, Rino Rappuoli, Michèle Anne Barocchi, Paolo Ruggiero

Molecular Genomics

  • Molecular Genomics | Spotlight
    A Genomic Island of the Pathogen Leptospira interrogans Serovar Lai Can Excise from Its Chromosome
    Pascale Bourhy, Laurence Salaün, Aurélie Lajus, Claudine Médigue, Caroline Boursaux-Eude, Mathieu Picardeau

Bacterial Infections

  • Bacterial Infections
    Involvement of a Salmonella Genomic Island 1 Gene in the Rumen Protozoan-Mediated Enhancement of Invasion for Multiple-Antibiotic-Resistant Salmonella enterica Serovar Typhimurium
    Steve A. Carlson, Vijay K. Sharma, Zoe P. McCuddin, Mark A. Rasmussen, Sharon K. Franklin
  • Bacterial Infections
    Reduced Phase Switch Capacity and Functional Adhesin Expression of Type 1-Fimbriated Escherichia coli from Immunoglobulin A-Deficient Individuals
    Forough L. Nowrouzian, Vanda Friman, Ingegerd Adlerberth, Agnes E. Wold
  • Bacterial Infections
    Identification of Helicobacter pylori Genes That Contribute to Stomach Colonization
    David N. Baldwin, Benjamin Shepherd, Petra Kraemer, Michael K. Hall, Laura K. Sycuro, Delia M. Pinto-Santini, Nina R. Salama
  • Bacterial Infections
    Francisella tularensis Replicates within Alveolar Type II Epithelial Cells In Vitro and In Vivo following Inhalation
    Joshua D. Hall, Robin R. Craven, James R. Fuller, Raymond J. Pickles, Thomas H. Kawula
  • Bacterial Infections
    Surface Proteins and Exotoxins Are Required for the Pathogenesis of Staphylococcus aureus Pneumonia
    Juliane Bubeck Wardenburg, Ravi J. Patel, Olaf Schneewind
  • Bacterial Infections
    Hypervirulence of a Rough Variant of the Mycobacterium abscessus Type Strain
    E. Catherinot, J. Clarissou, G. Etienne, F. Ripoll, J.-F. Emile, M. Daffé, C. Perronne, C. Soudais, J.-L. Gaillard, M. Rottman

Author's Correction

  • Author's Correction
    Role of FliF and FliI of Listeria monocytogenes in Flagellar Assembly and Pathogenicity
    Armelle Bigot, Hélène Pagniez, Eléonore Botton, Claude Fréhel, Iharilalao Dubail, Christine Jacquet, Alain Charbit, Catherine Raynaud
PreviousNext
Back to top

Infection and Immunity: 75 (2)

In This Issue

volume 75, issue 2
  • Table of Contents (PDF)
  • Journal Cover & Description
  • Masthead (PDF)
Sign up for alerts

Jump to

  • Spotlight
  • Minireviews
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
  • Molecular Pathogenesis
  • Host Response and Inflammation
  • Fungal and Parasitic Infections
  • Microbial Immunity and Vaccines
  • Molecular Genomics
  • Bacterial Infections
  • Author's Correction
  • Most Read
  • Most Cited
Loading
  • Pathogenic Mannheimia haemolytica Invades Differentiated Bovine Airway Epithelial Cells
  • Fitness Trade-Offs Resulting from Bacteriophage Resistance Potentiate Synergistic Antibacterial Strategies
  • An Ixodes scapularis Protein Disulfide Isomerase Contributes to Borrelia burgdorferi Colonization of the Vector
  • Success of Escherichia coli O25b:H4 Sequence Type 131 Clade C Associated with a Decrease in Virulence
More...

About

  • About IAI
  • Editor in Chief
  • Editorial Board
  • Policies
  • For Reviewers
  • For the Media
  • For Librarians
  • For Advertisers
  • Alerts
  • RSS
  • FAQ
  • Permissions
  • Journal Announcements

Authors

  • ASM Author Center
  • Submit a Manuscript
  • Article Types
  • Ethics
  • Contact Us

Follow #IAIjournal

@ASMicrobiology

       

ASM Journals

ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology.

About ASM | Contact Us | Press Room

 

ASM is a member of

Scientific Society Publisher Alliance

 

American Society for Microbiology
1752 N St. NW
Washington, DC 20036
Phone: (202) 737-3600

Copyright © 2021 American Society for Microbiology | Privacy Policy | Website feedback

Print ISSN: 0019-9567; Online ISSN: 1098-5522