Journal Cover & Description
Cover image

Cover photograph (Copyright © 2008, American Society for Microbiology. All Rights Reserved.): Citrobacter rodentium infection in mice leads to increased expression of the chemokine macrophage inflammatory protein 3α and dendritic cell recruitment to the infected colon. By day 2 postinfection, numerous CD11c+ cells (green) are detected in the subepithelial region of the infected colon, in close proximity to epithelial cells infected by C. rodentium. The C. rodentium effector protein Tir (red) designates the location of C. rodentium-infected epithelial cells. 4′,6-Diamidino-2-phenylindole staining (blue) shows the host cell nuclei. (See related article on p. 1410.)