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Infection and Immunity
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Table of Contents

December 2009; Volume 77,Issue 12

Spotlight

  • Free
    Spotlight
    Articles of Significant Interest Selected from This Issue by the Editors

Minireviews

  • Minireview
    Toxin-Mediated Effects on the Innate Mucosal Defenses: Implications for Enteric Vaccines
    Gregory M. Glenn, David H. Francis, E. Michael Danielsen

Fungal and Parasitic Infections

  • Fungal and Parasitic Infections
    The Glycosylphosphatidylinositol-Anchored Protease Sap9 Modulates the Interaction of Candida albicans with Human Neutrophils
    Anke Hornbach, Antje Heyken, Lydia Schild, Bernhard Hube, Jürgen Löffler, Oliver Kurzai
  • Fungal and Parasitic Infections
    MyD88-Deficient Mice Exhibit Decreased Parasite-Induced Immune Responses but Reduced Disease Severity in a Murine Model of Neurocysticercosis
    Bibhuti B. Mishra, Uma Mahesh Gundra, Kondi Wong, Judy M. Teale
  • Fungal and Parasitic Infections
    Long-Term Immunity to Lethal Acute or Chronic Type II Toxoplasma gondii Infection Is Effectively Induced in Genetically Susceptible C57BL/6 Mice by Immunization with an Attenuated Type I Vaccine Strain
    Jason P. Gigley, Barbara A. Fox, David J. Bzik
  • Fungal and Parasitic Infections
    Th2 but Not Th1 Immune Bias Results in Altered Lung Functions in a Murine Model of Pulmonary Cryptococcus neoformans Infection
    Aditya V. Jain, Yanmei Zhang, W. Bradley Fields, David A. McNamara, Mun Y. Choe, Gwo-hsiao Chen, John Erb-Downward, John J. Osterholzer, Galen B. Toews, Gary B. Huffnagle, Michal A. Olszewski
  • Fungal and Parasitic Infections
    Malaria Ookinete Surface Protein-Based Vaccination via the Intranasal Route Completely Blocks Parasite Transmission in both Passive and Active Vaccination Regimens in a Rodent Model of Malaria Infection
    Takeshi Arakawa, Mayumi Tachibana, Takeshi Miyata, Tetsuya Harakuni, Hideyasu Kohama, Yasunobu Matsumoto, Naotoshi Tsuji, Hajime Hisaeda, Anthony Stowers, Motomi Torii, Takafumi Tsuboi
  • Fungal and Parasitic Infections
    Molecular Characterization of EmABP, an Apolipoprotein A-I Binding Protein Secreted by the Echinococcus multilocularis Metacestode
    Peter Bernthaler, Kerstin Epping, Gerd Schmitz, Peter Deplazes, Klaus Brehm
  • Fungal and Parasitic Infections
    12/15-Lipoxygenase-Dependent Myeloid Production of Interleukin-12 Is Essential for Resistance to Chronic Toxoplasmosis
    Melissa K. Middleton, Alicia M. Zukas, Tanya Rubinstein, Michelle Kinder, Emma H. Wilson, Peijuan Zhu, Ian A. Blair, Christopher A. Hunter, Ellen Puré
  • Fungal and Parasitic Infections
    Vaccine Potentials of an Intrinsically Unstructured Fragment Derived from the Blood Stage-Associated Plasmodium falciparum Protein PFF0165c
    S. Olugbile, C. Kulangara, G. Bang, S. Bertholet, E. Suzarte, V. Villard, G. Frank, R. Audran, A. Razaname, I. Nebie, O. Awobusuyi, F. Spertini, A. V. Kajava, I. Felger, P. Druilhe, G. Corradin

Molecular Pathogenesis

  • Molecular Pathogenesis
    The Secreted Esterase of Group A Streptococcus Is Important for Invasive Skin Infection and Dissemination in Mice
    Hui Zhu, Mengyao Liu, Paul Sumby, Benfang Lei
  • Molecular Pathogenesis
    Bcl-2 Regulates the Onset of Shiga Toxin 1-Induced Apoptosis in THP-1 Cells
    Moo-Seung Lee, Rama P. Cherla, Dinorah Leyva-Illades, Vernon L. Tesh
  • Molecular Pathogenesis
    OmpA of Uropathogenic Escherichia coli Promotes Postinvasion Pathogenesis of Cystitis
    Tracy F. Nicholson, Kristin M. Watts, David A. Hunstad
  • Molecular Pathogenesis
    Role for the Burkholderia pseudomallei Capsular Polysaccharide Encoded by the wcb Operon in Acute Disseminated Melioidosis
    Jonathan M. Warawa, Dan Long, Rebecca Rosenke, Don Gardner, Frank C. Gherardini
  • Molecular Pathogenesis
    Proteomic Analysis of Rickettsia parkeri Strain Portsmouth
    Walairat Pornwiroon, Apichai Bourchookarn, Christopher D. Paddock, Kevin R. Macaluso
  • Molecular Pathogenesis
    A Naturally Occurring Rgg Variant in Serotype M3 Streptococcus pyogenes Does Not Activate speB Expression Due to Altered Specificity of DNA Binding
    Kyle V. Kappeler, Srivishnupriya Anbalagan, Alexander V. Dmitriev, Emily J. McDowell, Melody N. Neely, Michael S. Chaussee
  • Molecular Pathogenesis
    Pyruvate Formate Lyase Is Required for Pneumococcal Fermentative Metabolism and Virulence
    Hasan Yesilkaya, Francesca Spissu, Sandra M. Carvalho, Vanessa S. Terra, Karen A. Homer, Rachel Benisty, Nurith Porat, Ana R. Neves, Peter W. Andrew
  • Molecular Pathogenesis
    Characterization of a Campylobacter jejuni VirK Protein Homolog as a Novel Virulence Determinant
    Veronica Novik, Dirk Hofreuter, Jorge E. Galán
  • Molecular Pathogenesis
    Molecular, Antigenic, and Functional Characteristics of Ferric Enterobactin Receptor CfrA in Campylobacter jejuni
    Ximin Zeng, Fuzhou Xu, Jun Lin
  • Molecular Pathogenesis
    oxyR, a LysR-Type Regulator Involved in Klebsiella pneumoniae Mucosal and Abiotic Colonization
    Claire Hennequin, Christiane Forestier
  • Molecular Pathogenesis | Spotlight
    Effect of the O-Antigen Length of Lipopolysaccharide on the Functions of Type III Secretion Systems in Salmonella enterica
    Stefanie U. Hölzer, Markus C. Schlumberger, Daniela Jäckel, Michael Hensel
  • Molecular Pathogenesis | Spotlight
    Leptospira interrogans Binds to Human Cell Surface Receptors Including Proteoglycans
    Deborah D. Breiner, Mark Fahey, Ryan Salvador, Jana Novakova, Jenifer Coburn
  • Molecular Pathogenesis
    Instantaneous Within-Patient Diversity of Pseudomonas aeruginosa Quorum-Sensing Populations from Cystic Fibrosis Lung Infections
    Cara N. Wilder, Gopal Allada, Martin Schuster

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions

  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    The Sca2 Autotransporter Protein from Rickettsia conorii Is Sufficient To Mediate Adherence to and Invasion of Cultured Mammalian Cells
    Marissa M. Cardwell, Juan J. Martinez
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Spa15 of Shigella flexneri Is Secreted through the Type III Secretion System and Prevents Staurosporine-Induced Apoptosis
    Christina S. Faherty, Anthony T. Maurelli
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Antiapoptotic Proteins Bcl-2 and Bcl-XL Inhibit Clostridium difficile Toxin A-Induced Cell Death in Human Epithelial Cells
    Isabelle Matte, Denis Lane, Élodie Côté, Ann-Élise Asselin, Louis-Charles Fortier, Claude Asselin, Alain Piché
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    The Enteropathogenic Escherichia coli Effector Cif Induces Delayed Apoptosis in Epithelial Cells
    Ascel Samba-Louaka, Jean-Philippe Nougayrède, Claude Watrin, Eric Oswald, Frédéric Taieb
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Surface-Exposed Histone-Like Protein A Modulates Adherence of Streptococcus gallolyticus to Colon Adenocarcinoma Cells
    Annemarie Boleij, Renée M. J. Schaeps, Stan de Kleijn, Peter W. Hermans, Philippe Glaser, Vijay Pancholi, Dorine W. Swinkels, Harold Tjalsma
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    CD23 Mediates Antimycobacterial Activity of Human Macrophages
    M. Djavad Mossalayi, Ioannis Vouldoukis, Maria Mamani-Matsuda, Tina Kauss, Jean Guillon, Jeanne Maugein, Daniel Moynet, Jérôme Rambert, Vanessa Desplat, Dominique Mazier, Philippe Vincendeau, Denis Malvy
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Bacterial Toxins Induce Sustained mRNA Expression of the Silencing Transcription Factor klf2 via Inactivation of RhoA and Rhophilin 1
    Kristina Dach, Josip Zovko, Michael Hogardt, Isabel Koch, Katrin van Erp, Jürgen Heesemann, Reinhard Hoffmann
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    The Long-Lived Nature of Clostridium perfringens Iota Toxin in Mammalian Cells Induces Delayed Apoptosis
    Hanna Hilger, Sascha Pust, Guido von Figura, Eva Kaiser, Bradley G. Stiles, Michel R. Popoff, Holger Barth
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Inhibition of Erythrocyte Invasion and Plasmodium falciparum Merozoite Surface Protein 1 Processing by Human Immunoglobulin G1 (IgG1) and IgG3 Antibodies
    Maria Lazarou, José A. Guevara Patiño, Richard M. Jennings, Richard S. McIntosh, Jianguo Shi, Steven Howell, Eilish Cullen, Tarran Jones, Jaime R. Adame-Gallegos, Jonathan A. Chappel, Jana S. McBride, Michael J. Blackman, Anthony A. Holder, Richard J. Pleass
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Complement Receptor 3 Deficiency Influences Lesion Progression during Leishmania major Infection in BALB/c Mice
    Cristina R. Carter, James P. Whitcomb, Jessica A. Campbell, Rami M. Mukbel, Mary Ann McDowell
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Rhodococcus equi Virulence-Associated Protein A Is Required for Diversion of Phagosome Biogenesis but Not for Cytotoxicity
    Kristine von Bargen, Marco Polidori, Ulrike Becken, Gitta Huth, John F. Prescott, Albert Haas

Bacterial Infections

  • Bacterial Infections
    Development and Application of New Mouse Models To Study the Pathogenesis of Clostridium perfringens Type C Enterotoxemias
    Francisco A. Uzal, Juliann Saputo, Sameera Sayeed, Jorge E. Vidal, Derek J. Fisher, Rachael Poon, Vicki Adams, Mariano E. Fernandez-Miyakawa, Julian I. Rood, Bruce A. McClane
  • Bacterial Infections
    Distinctive Profiles of Infection and Pathology in Hamsters Infected with Clostridium difficile Strains 630 and B1
    David Goulding, Harold Thompson, Jenny Emerson, Neil F. Fairweather, Gordon Dougan, Gill R. Douce
  • Bacterial Infections
    C3H Male Mice with Severe Combined Immunodeficiency Cannot Clear a Urethral Infection with a Human Serovar of Chlamydia trachomatis
    Sukumar Pal, Annahita K. Sarcon, Luis M. de la Maza
  • Bacterial Infections
    Bacterial Growth Rate and Host Factors as Determinants of Intracellular Bacterial Distributions in Systemic Salmonella enterica Infections
    Andrew J. Grant, Gemma L. Foster, Trevelyan J. McKinley, Sam P. Brown, Simon Clare, Duncan J. Maskell, Pietro Mastroeni
  • Bacterial Infections
    Coxiella burnetii Isolates Cause Genogroup-Specific Virulence in Mouse and Guinea Pig Models of Acute Q Fever
    K. E. Russell-Lodrigue, M. Andoh, M. W. J. Poels, H. R. Shive, B. R. Weeks, G. Q. Zhang, C. Tersteeg, T. Masegi, A. Hotta, T. Yamaguchi, H. Fukushi, K. Hirai, D. N. McMurray, J. E. Samuel
  • Bacterial Infections | Spotlight
    Persistent Infection Contributes to Heterologous Protective Immunity against Fatal Ehrlichiosis
    Nagaraja R. Thirumalapura, Emily C. Crossley, David H. Walker, Nahed Ismail

Host Response and Inflammation

  • Host Response and Inflammation
    Inescapable Need for Neutrophils as Mediators of Cellular Innate Immunity to Acute Pseudomonas aeruginosa Pneumonia
    Andrew Y. Koh, Gregory P. Priebe, Christopher Ray, Nico Van Rooijen, Gerald B. Pier
  • Host Response and Inflammation
    Mycobacterium tuberculosis Culture Filtrate Proteins plus CpG Oligodeoxynucleotides Confer Protection to Mycobacterium bovis BCG-Primed Mice by Inhibiting Interleukin-4 Secretion
    Denise Morais da Fonseca, Celio Lopes Silva, Pryscilla Fanini Wowk, Marina Oliveira e Paula, Simone Gusmão Ramos, Cynthia Horn, Gilles Marchal, Vânia Luiza Deperon Bonato
  • Host Response and Inflammation | Spotlight
    Uropathogenic Escherichia coli Suppresses the Host Inflammatory Response via Pathogenicity Island Genes sisA and sisB
    Amanda L. Lloyd, Sara N. Smith, Kathryn A. Eaton, Harry L. T. Mobley
  • Host Response and Inflammation
    Critical Role for Interleukin-1β (IL-1β) during Chlamydia muridarum Genital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages
    Daniel Prantner, Toni Darville, James D. Sikes, Charles W. Andrews, Helmut Brade, Roger G. Rank, Uma M. Nagarajan
  • Host Response and Inflammation
    Helminth Infection Can Reduce Insulitis and Type 1 Diabetes through CD25- and IL-10-Independent Mechanisms
    Qian Liu, Krishnan Sundar, Pankaj K. Mishra, Gity Mousavi, Zhugong Liu, Andrew Gaydo, Farhang Alem, David Lagunoff, David Bleich, William C. Gause
  • Host Response and Inflammation
    Histamine Plays an Essential Regulatory Role in Lung Inflammation and Protective Immunity in the Acute Phase of Mycobacterium tuberculosis Infection
    D. Carlos, C. Fremond, A. Samarina, V. Vasseur, I. Maillet, S. G. Ramos, F. Erard, V. Quesniaux, H. Ohtsu, C. L. Silva, L. H. Faccioli, B. Ryffel
  • Host Response and Inflammation
    Frequencies of Region of Difference 1 Antigen-Specific but Not Purified Protein Derivative-Specific Gamma Interferon-Secreting T Cells Correlate with the Presence of Tuberculosis Disease but Do Not Distinguish Recent from Remote Latent Infections
    Timothy S. C. Hinks, Davinder P. S. Dosanjh, John A. Innes, Geoffrey Pasvol, Sarah Hackforth, Hansa Varia, Kerry A. Millington, Xiao-Qing Liu, Mustafa Bakir, Ahmet Soysal, Robert N. Davidson, Rubamalar Gunatheesan, Ajit Lalvani
  • Host Response and Inflammation
    Partial Protection against Helicobacter pylori in the Absence of Mast Cells in Mice
    Hua Ding, John G. Nedrud, Barry Wershil, Raymond W. Redline, Thomas G. Blanchard, Steven J. Czinn
  • Host Response and Inflammation
    Enterococcus faecalis Capsular Polysaccharide Serotypes C and D and Their Contributions to Host Innate Immune Evasion
    Lance R. Thurlow, Vinai Chittezham Thomas, Sherry D. Fleming, Lynn E. Hancock
  • Host Response and Inflammation
    Saliva Enables the Antimicrobial Activity of LL-37 in the Presence of Proteases of Porphyromonas gingivalis
    Michal Gutner, Stella Chaushu, Daniela Balter, Gilad Bachrach
  • Host Response and Inflammation
    Toll-Like Receptor Signaling in Airborne Burkholderia thailandensis Infection
    T. Eoin West, Thomas R. Hawn, Shawn J. Skerrett
  • Host Response and Inflammation
    Toll-Like Receptors 2 and 4 Contribute to Sepsis-Induced Depletion of Spleen Dendritic Cells
    Frédéric Pène, Emilie Courtine, Fatah Ouaaz, Benjamin Zuber, Bertrand Sauneuf, Gonzalo Sirgo, Christophe Rousseau, Julie Toubiana, Viviane Balloy, Michel Chignard, Jean-Paul Mira, Jean-Daniel Chiche

Microbial Immunity and Vaccines

  • Microbial Immunity and Vaccines
    Superior Protective Immunity against Murine Listeriosis by Combined Vaccination with CpG DNA and Recombinant Salmonella enterica Serovar Typhimurium
    Christina Berchtold, Klaus Panthel, Stefan Jellbauer, Brigitte Köhn, Elisabeth Roider, Miriam Partilla, Jürgen Heesemann, Stefan Endres, Carole Bourquin, Holger Rüssmann
  • Microbial Immunity and Vaccines
    A Heterologous Helper T-Cell Epitope Enhances the Immunogenicity of a Multiple-Antigenic-Peptide Vaccine Targeting the Cryptic Loop-Neutralizing Determinant of Bacillus anthracis Protective Antigen
    Jon Oscherwitz, Fen Yu, Kemp B. Cease
  • Microbial Immunity and Vaccines
    Regulated Delayed Expression of rfaH in an Attenuated Salmonellaenterica Serovar Typhimurium Vaccine Enhances Immunogenicity of Outer Membrane Proteins and a Heterologous Antigen
    Qingke Kong, Qing Liu, Kenneth L. Roland, Roy Curtiss
  • Microbial Immunity and Vaccines
    Vaccination with the ML0276 Antigen Reduces Local Inflammation but Not Bacterial Burden during Experimental Mycobacteriumleprae Infection
    Vanitha S. Raman, Joanne O'Donnell, H. Remy Bailor, Wakako Goto, Ramanuj Lahiri, Thomas P. Gillis, Steven G. Reed, Malcolm S. Duthie

Errata

  • Errata
    Characterization of a Unique ADP-Ribosyltransferase of Mycoplasma penetrans
    Coreen Johnson, T. R. Kannan, Joel B. Baseman
  • Errata
    Volume 77, no. 10, 2009, Cover Caption
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Infection and Immunity: 77 (12)

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volume 77, issue 12
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